It’s only fair to share… Rivasterat CAS 2446590-96-9 MF C37H54O8 MW626.8 g/mol methyl (E)-6-[(3S,8S,9S,10R,13S,14S,17R)-3-[[(2R,3S,6S)-3-acetyloxy-2-(acetyloxymethyl)-3,6-dihydro-2H-pyran-6-yl]oxy]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]hept-5-enoate 27-NORCHOLESTA-5,20(22)-DIEN-26-OIC ACID, 3-((4,6-DI-O-ACETYL-2,3-DIDEOXY-.ALPHA.-D-ERYTHRO-HEX-2-ENOPYRANOSYL)OXY)-, METHYL ESTER, (3.BETA.,20E)- methyl (20E)-3β-[(4,6-di-O-acetyl-2,3-dideoxy-α-Derythro-hex-2-enopyranosyl)oxy]-27-norcholesta5,20(22)-dien-26-oatecholesterol-derived steroid, anti-inflammatory, CURACLE, CU-06, CU-06-RE, CU06-1004, CU06-CERE/CV, CU06-EYE, CU06-HAE, CU06-IBD, CU06-ONCO, Sac-1004, 2X23JA5AKW Developer and Code Name This class of drugs aims to restore endothelial barrier integrity rather than directly blocking VEGF like most …
Category «Uncategorized»
Repinatrabit
It’s only fair to share… Repinatrabit CAS 2837993-05-0 MF C18H22F4N4O3 MW 418.4 g/mol (3R)-3-[cyclopropyl-[[2-fluoro-4-(trifluoromethoxy)phenyl]methylcarbamoyl]amino]piperidine-1-carboxamide (3R)-3-[cyclopropyl({[2-fluoro-4-(trifluoromethoxy)phenyl]methyl}carbamoyl)amino]piperidine-1-carboxamidesolute carrier family 6 member 19 (SLC6A19) inhibitor(phenylketonuria), JNT-517, JNT 517, orphan drug, rare pediatric disease designations, Jnana Therapeutics, 5P44NDU6AC, JN 11804, JN-11804 Repinatrabit (JNT-517) is an investigational, oral, small-molecule drug developed by Jnana Therapeutics (now part of Otsuka Pharmaceutical) to treat Phenylketonuria …
Remlifanserin
It’s only fair to share… Remlifanserin CAS 2289704-13-6 MF C24H29F2N3O2 MW 429.5 g/mol 3-[(4-cyclopropyloxyphenyl)methyl]-1-[(2,4-difluorophenyl)methyl]-1-(1-methylpiperidin-4-yl)urea N’-{[4-(cyclopropyloxy)phenyl]methyl}-N-[(2,4-difluorophenyl)methyl]-N-(1-methylpiperidin-4-yl)ureaserotonin receptor (5-HT2A) inverse agonist, ACP-204, ACP 204, H4L2AF2XB7 Remlifanserin is a small molecule drug. The usage of the INN stem ‘-anserin’ in the name indicates that Remlifanserin is a serotonin receptor antagonist. Remlifanserin has a monoisotopic molecular weight of 429.22 Da. Remlifanserin (INNTooltip International …
Relicpixant
It’s only fair to share… Relicpixant CAS 2445366-94-7 MF C20H19ClF2N4O5S, Mw 500.9 g/mol methyl (2S)-2-{[7-chloro-2-(2,6-difluoro-4-sulfamoylphenyl)imidazo[1,2-a]pyridin-3-yl]methyl}morpholine-4-carboxylatepurinoreceptor (P2X) antagonist, 3NWJ8FHG2R Relicpixant is a small molecule drug. The usage of the INN stem ‘-pixant’ in the name indicates that Relicpixant is a purinoreceptor (P2X) antagonist. Relicpixant has a monoisotopic molecular weight of 500.07 Da. SYN US20240034729, https://patentscope.wipo.int/search/en/detail.jsf?docId=US393005051&_cid=P10-MMH5CF-50302-1 Example 172 …
Ranosidenib
It’s only fair to share… Ranosidenib CAS 2301974-60-5 MF C15H16F9N5O MW 453.31 g/mol (1S)-3-[4,6-bis[[(2R)-1,1,1-trifluoropropan-2-yl]amino]-1,3,5-triazin-2-yl]-2,6,6-trifluorocyclohex-2-en-1-ol (1S)-3-(4,6-bis{[(2R)-1,1,1-trifluoropropan-2-yl]amino}-1,3,5-triazin-2-yl)-2,6,6-trifluorocyclohex-2-en-1-olisocitrate dehydrogenase (IDH) inhibitor, antineoplastic, [14C] HMPL-306, HMPL 306, PC64OXS2C2 Ranosidenib is a small molecule drug. Ranosidenib is under investigation in clinical trial NCT06387069 (A Study to Evaluate HMPL-306 in Patients With IDH1- and IDH2-mutated Acute Myeloid Leukemia). Ranosidenib has a monoisotopic …
PROGERININ
It’s only fair to share… Progerinin CAS 2249696-72-6 MF C23H22O4 MW 362.42 (3S)-2,2-dimethyl-3-[(E)-3-phenylprop-2-enoxy]-3,4-dihydropyrano[3,2-g]chromen-8-one (7S)-(+)-8,8-dimethyl-7-(3-phenyl-allyloxy)-7,8-dihydro-6H-pyrano[3,2-g]chromen-2-one (7S)-7,8-Dihydro-8,8-dimethyl-7-[[(2E)-3-phenyl-2-propen-1-yl]oxy]-2H,6H-benzo[1,2-b:5,4-b?]dipyran-2-one (7S)-8,8-dimethyl-7-{[(2E)-3-phenylprop-2-en-1-yl]oxy}-7,8-dihydro-2H,6H-benzo[1,2-b:5,4-b’]dipyran-2-oneprogerin-lamin A binding inhibitor, SLC-D011, SLC D011, KC 3, 426P9HSR8I Progerinin (SLC-D011) is an orally active, targeted inhibitor designed to reduce the toxic, premature-aging protein “progerin” in Hutchinson-Gilford Progeria Syndrome (HGPS). It binds to progerin, disrupting its interaction with lamin A …
Lead (212Pb) bamzireotide navoxetan
It’s only fair to share… Lead (212Pb) bamzireotide navoxetan CAS 2941523-47-1 MF C72H104N16O20212PbS2 MW1789.8 g/mol 2-[4-[2-[2-[2-[3-[[(2R)-1-[[(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-4-[[(2R,3R)-1,3-dihydroxybutan-2-yl]carbamoyl]-7-[(1R)-1-hydroxyethyl]-16-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicos-19-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-oxopropoxy]ethoxy]ethylamino]-2-oxoethyl]-10-(2-amino-2-oxoethyl)-7-(carboxylatomethyl)-1,4,7,10-tetrazacyclododec-1-yl]acetate;lead-212(2+) ANTINEOPLASTIC, D2A42X3LCS SYN US 11037690 B2 AS ON FEB2026 4.574 LAKHS VIEWS ON BLOG WORLDREACH AVAILABLEFOR YOUR ADVERTISEMENT join me on Linkedin Anthony Melvin Crasto Ph.D – India | LinkedIn join me on Researchgate RESEARCHGATE join me on Facebook Anthony Melvin Crasto Dr. …
Pixavir marboxil
It’s only fair to share… Pixavir marboxil CAS 2365473-17-0 MF C27H22F2N2O6S MW540.535 (1-((11S)-7,8-DIFLUORO-6,11-DIHYDROBENZO(C)(1)BENZOTHIEPIN-11-YL)-4,6-DIOXOSPIRO(2H-PYRIDO(1,2-B)PYRIDAZINE-3,1′-CYCLOPROPANE)-5-YL)OXYMETHYL METHYL CARBONATE ({1′-[(11S)-7,8-difluoro-6,11-dihydrodibenzo[b,e]thiepin-11-yl]-4′,6′-dioxo1′,2′,4′,6′-tetrahydrospiro[cyclopropane-1,3′-pyrido[1,2-b]pyridazin]-5′-yl}oxy)methyl methyl carbonateantiviral, TG 1000, Yi Li Kang, SV42843XSX, Cap-dependent endonuclease-IN-1, Influenza virus infections, TaiGen Biotechnology Pixavir marboxil (also known as TG-1000) is an investigational antiviral drug designed to treat and inhibit influenza virus infections. It belongs to a class …
Navepegritide
It’s only fair to share… Navepegritide Cas 2413551-27-4 Molecular Formula: C₂₃₁H₃₈₆N₆₄O₆₇S₅ + (C₂H₄O)₄ₙ (approx. 45 kDa), 1804.0 g/mol MOLECULAR FORMULA C231H386N64O67S5 + (C2H4O)4nMOLECULAR WEIGHT approx. 45 kDa The structure of navepegritide (YUVIWEL®) is built using a “prodrug” design. It is not a simple small molecule, but rather a complex conjugate consisting of three distinct components designed to release the active …
Pebezertinib
It’s only fair to share… Pebezertinib CAS 2769954-39-2 MF C24H19F4N7O MW 497.4 g/mol N-[4-fluoro-3-[[2-[(1-methylpyrazol-4-yl)amino]-5-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl]amino]phenyl]prop-2-enamide N-[4-fluoro-3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-5-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl}amino)phenyl]prop-2-enamideepidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, antineoplastic, BLU 451, BLU 203139, G8G5AU5GLJ, LNG 451 Pebezertinib is a small molecule drug. The usage of the INN stem ‘-ertinib’ in the name indicates that Pebezertinib is a epidermal growth factor receptor (EGFR) …