It’s only fair to share… Iguratimod Molecular FormulaC17H14N2O6S Average mass374.368 Da UNII-4IHY34Y2NV игуратимод إيغوراتيمود 艾拉莫德 123663-49-0 [RN] 3-Formylamino-7-methylsulfonylamino-6-phenoxy-4H-1-benzopyran-4-one 4IHY34Y2NV 8176 IGU Methanesulfonamide, N-[3-(formylamino)-4-oxo-6-phenoxy-4H-1-benzopyran-7-yl]- N-(3-Formamido-4-oxo-6-phenoxy-4H-chromen-7-yl)methanesulfonamide product patent US4954518 Research Code： T-614 Trade Name： Iremod® / Kolbet® / Careram® MOA： Nuclear factor NF-κB activation inhibitor Indication： Rheumatoid arthritis Status： Approved Company： Simcere (Originator) , Taisho Toyama,Eisai Sales： ATC Code： Approved Countries or Area JP …
Category «Uncategorized»
RIDINILAZOLE
It’s only fair to share… RIDINILAZOLE SMT19969 Molecular FormulaC24H16N6 Average mass388.424 Da ридинилазол [Russian] [INN] ريدينيلازول [Arabic] [INN] 利地利唑 [Chinese] [INN] リジニラゾール; 10075 2,2′-Di(4-pyridinyl)-3H,3’H-5,5′-bibenzimidazole 308362-25-6 [RN] 6,6′-Bi-1H-benzimidazole, 2,2′-di-4-pyridinyl- Summit Therapeutics (formerly Summit Corp ) is developing ridinilazole the lead compound from oral narrow-spectrum, GI-restricted antibiotics, which also include SMT-21829, for the treatment of Clostridium difficile infection and prevention of recurrent disease. …
OI 338
It’s only fair to share… OI 338 OI338GT (NN1953) NNC0123-0000-0338 Insulin oral (NN 1953); Insulin-338-GIPET-I; LAI 338; NN 1438; NN-1953; NNC-0123-0000-0338; NNC0123-0338; OI-338GT; Oral insulin 338 C10 OriginatorNovo Nordisk ClassAntihyperglycaemics; Insulins; Pancreatic hormones Mechanism of ActionOrnithine decarboxylase stimulants; Phosphokinase stimulants; Protein tyrosine kinase stimulants Phase IIType 1 diabetes mellitus; Type 2 diabetes mellitus 28 Jul …
Fosnetupitant
It’s only fair to share… Fosnetupitant Molecular FormulaC31H35F6N4O5P Average mass688.598 Da [4-[5-[[2-[3,5-bis(trifluoromethyl)phenyl]-2-methylpropanoyl]-methylamino]-4-(2-methylphenyl)pyridin-2-yl]-1-methylpiperazin-1-ium-1-yl]methyl hydrogen phosphate (4-{5-[{2-[3,5-Bis(trifluoromethyl)phenyl]-2-methylpropanoyl}(methyl)amino]-4-(2-methylphenyl)-2-pyridinyl}-1-methylpiperazin-1-ium-1-yl)methyl hydrogen phosphate 07-PNET 10146 CAS 1703748-89-3 HCL 1643757-72-5 FDA 2014 AND EMA 2015 Фоснетупитант [Russian] [INN] فوسنيتوبيتانت [Arabic] [INN] 磷奈匹坦 [Chinese] [INN] 07-PNET In April 2018, the U.S. Food and Drug Administration (FDA) and the Swiss company Helsinn approved the intravenous formulation of AKYNZEO® (NEPA, a fixed antiemetic combination …
Centhaquine
It’s only fair to share… Centhaquine PMZ-2010 CAS 57961-90-7 2-[2-[4-(3-methylphenyl)piperazin-1-yl]ethyl]quinoline INDIA 2020, 14.05.2020, Centhaquine citrate bulk and Centhaquine citrate injection 1.0mg/vial, Add on resuscitative agent for hypovolemic shock OriginatorMidwestern University; Pharmazz DeveloperPharmazz ClassAnalgesics; Antihaemorrhagics; Antihypertensives; Cardiovascular therapies; Piperazines; Quinolines; Small molecules Mechanism of ActionAlpha 1 adrenergic receptor antagonists; Alpha 2 adrenergic receptor agonists RegisteredHaemorrhagic shock Phase IHeart …
Esketamine
It’s only fair to share… Esketamine Molecular FormulaC13H16ClNO Average mass237.725 Da (+)-Ketamine (2S)-2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone (S)-Ketamine 33643-46-8 [RN] 7884 Cyclohexanone, 2-(2-chlorophenyl)-2-(methylamino)-, (2S)- Cyclohexanone, 2-(2-chlorophenyl)-2-(methylamino)-, (S)- Ketamine CAS Registry Number: 6740-88-1 CAS Name: 2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone Molecular Formula: C13H16ClNO Molecular Weight: 237.73 Percent Composition: C 65.68%, H 6.78%, Cl 14.91%, N 5.89%, O 6.73% Literature References: Prepn: C. L. Stevens, BE634208; idem,US3254124 (1963, 1966 both to Parke, Davis). Isoln of …
Inclisiran
It’s only fair to share… Inclisiran CAS 1639324-58-5 ALN-60212 ALN-PCSsc Inclisiran was first developed by Alnylam Pharmaceuticals, Inc. (Cambridge, Massachusetts, US). Development has now been assumed by The Medicines Company (Parsippany, New Jersey, US). One phase I and two phase II trials have been completed. Topline results of two phase III trials were also recently …
Ciglitazone
It’s only fair to share… Ciglitazone U-63287, ADD-3878 Molecular FormulaC18H23NO3S Average mass333.445 Da 74772-77-3 [RN] (±)-5-[4-(1-Methylcyclohexylmethoxy)benzyl]thiazolidine-2,4-dione 2,4-Thiazolidinedione, 5-[[4-[(1-methylcyclohexyl)methoxy]phenyl]methyl]- 5-[4-(1-methylcyclohexylmethoxy) benzyl]-thiazolidine-2,4-dione Ciglitazone (INN) is a thiazolidinedione. Developed by Takeda Pharmaceuticals in the early 1980s, it is considered the prototypical compound for the thiazolidinedione class.[1][2][3][4] Ciglitazone was never used as a medication, but it sparked interest in the effects of thiazolidinediones. Several analogues were …
BMS 262084
It’s only fair to share… BMS-262084 CAS 253174-92-4 Molecular FormulaC18H31N7O5 Average mass425.483 Da NII-I0IR71971G I0IR71971G (2S,3R)-1-[4-(tert-butylcarbamoyl)piperazine-1-carbonyl]-3-[3-(diaminomethylideneamino)propyl]-4-oxoazetidine-2-carboxylic acid (2S,3R)-1-{[4-(tert-butylcarbamoyl)piperazin-1-yl]carbonyl}-3-{3-[(diaminomethylidene)amino]propyl}-4-oxoazetidine-2-carboxylic acid (2S,3R)-3-{3-[(Diaminomethylene)amino]propyl}-1-({4-[(2-methyl-2-propanyl)carbamoyl]-1-piperazinyl}carbonyl)-4-oxo-2-azetidinecarboxylic acid 253174-92-4 [RN] 2-Azetidinecarboxylic acid, 3-[3-[(diaminomethylene)amino]propyl]-1-[[4-[[(1,1-dimethylethyl)amino]carbonyl]-1-piperazinyl]carbonyl]-4-oxo-, (2S,3R)- Factor XIa inhibitors (thrombosis), BMS; Factor XIa inhibitors (thrombosis), Bristol-Myers Squibb; BMS-654457; Factor XIa inhibitors (cardiovascular diseases), BMS; BMS-724296 Novel crystalline forms of BMS-262084 as Factor XIa antagonist useful for …
PERAMIVIR
It’s only fair to share… PERAMIVIR CAS 330600-85-6 Molecular FormulaC15H28N4O4 Average mass328.407 Da (1S,2S,3R,4R)-4-carbamimidamido-3-[(1S)-1-acetamido-2-ethylbutyl]-2-hydroxycyclopentane-1-carboxylic acid RWJ 270201 RWJ-270201 RWJ270201 (1S,2S,3R,4R)-3-(1-Acetamido-2-ethylbutyl)-4-carbamimidamido-2-hydroxycyclopentanecarboxylic acid [ACD/IUPAC Name] (1S,2S,3R,4R)-3-[(1S)-1-(Acetylamino)-2-ethylbutyl]-4-[(aminoiminomethyl)amino]-2-hydroxycyclopentanecarboxylic Acid (1S,2S,3R,4R)-3-[(1S)-1-Acetamido-2-ethylbutyl]-4-carbamimidamido-2-hydroxycyclopentanecarboxylic acid 229614-56-6 [RN] 330600-85-6 [RN] 8184 9ZS94HQO3B Peramivir, also known as BCX1812 and RWJ 270201, is an antiviral drug for the treatment of influenza. Peramivir is a neuraminidase inhibitor, acting as a transition-state …