Selective synthesis of dimethoxyethane via directly catalytic etherification of crude ethylene glycol

It’s only fair to share…   Selective synthesis of dimethoxyethane via directly catalytic etherification of crude ethylene glycol Green Chem., 2017, Advance Article DOI: 10.1039/C7GC00659D, Paper Weiqiang Yu, Fang Lu, Qianqian Huang, Rui Lu, Shuai Chen, Jie Xu A potential diesel fuel additive, dimethoxyethane, was highly selectively produced via etherification of crude ethylene glycol over …

Selective hydrogenation of N-heterocyclic compounds using Ru nanocatalysts in ionic liquids

It’s only fair to share…   Selective hydrogenation of N-heterocyclic compounds using Ru nanocatalysts in ionic liquids Green Chem., 2017, 19,2762-2767 DOI: 10.1039/C7GC00513J, Communication Hannelore Konnerth, Martin H. G. Prechtl N-Heterocyclic compounds have been tested in the selective hydrogenation catalysed by small 1-3 nm sized Ru nanoparticles (NPs) embedded in various imidazolium based ionic liquids …

Is water a suitable solvent for the catalytic amination of alcohols?

It’s only fair to share… Is water a suitable solvent for the catalytic amination of alcohols? Green Chem., 2017, 19,2839-2845 DOI: 10.1039/C7GC00422B, Paper Johannes Niemeier, Rebecca V. Engel, Marcus Rose The catalytic aqueous-phase amination of biogenic alcohols with solid catalysts is reported for future development of renewable amine value-added chains. From the journal: Green Chemistry …

Efficient and Stereoselective Syntheses of Isomerically Pure 4-Aminotetrahydro-2H-thiopyran 1-Oxide Derivatives

It’s only fair to share… trans-4-Aminotetrahydro-2H-thiopyran 1-Oxide Methanesulfonate (trans–3d-MsOH) Compound ……………….afforded trans-3d-MsOH (20 g, 68%) as a white crystalline solid. 1H NMR (300 MHz, DMSO-d6) δ 1.60–1.76 (2H, m), 2.16–2.29 (2H, m), 2.31 (3H, s), 2.68–2.81 (2H, m), 3.13–3.23 (2H, m), 3.27–3.35 (1H, m), 7.86 (3H, brs). 13C NMR (75 MHz, D2O) δ 24.98, 38.51, …

Tropylium salts as efficient organic Lewis acid catalysts for acetalization and transacetalization reactions in batch and flow

It’s only fair to share… Tropylium salts as efficient organic Lewis acid catalysts for acetalization and transacetalization reactions in batch and flow Green Chem., 2017, Advance Article DOI: 10.1039/C7GC01519D, Communication D. J. M. Lyons, R. D. Crocker, D. Enders, T. V. Nguyen Tropylium salts were reported as organic-Lewis acids to efficiently catalyze acetalization reactions in …

CP 11

It’s only fair to share…     Scheme 10 Synthesis of C60-PGN and C60-GAP. It has been calculated that the enthalpy of formation of Cp-5 is 2782.2 kJ mol−1, while its detonation velocity and pressure are 3282 km s−1 and 4.443 GPa, respectively.112 Upon complete combustion, the total heat of combustion for Cp-5 is 2.17 …

HNIW, CL 20, 六硝基六氮杂异伍兹烷

It’s only fair to share…   HNIW, CL-20 Molecular FormulaC6H6N12O12 Average mass438.185 Da 1,3,4,7,8,10-hexanitrooctahydro-1H-5,2,6-(epiminomethanetriylimino)imidazo[4,5-b]pyrazine CAS 135285-90-4 Hexanitrohexaazaisowurtzitane 2,4,6,8,10,12-Hexanitro-2,4,6,8,10,12-hexaazaisowurtzitane Octahydro-1,3,4,7,8,10-hexanitro-5,2,6-(iminomethenimino)-1H-imidazo[4,5-b]pyrazine HNIW 六硝基六氮杂异伍兹烷 ABOUT AUTHOR Tomasz Gołofit Warsaw University of Technolog… , Warsaw Thermochemistry, Physical Chemistry, Materials Chemistry Warsaw University of Technology Department of Energized Materials Warsaw, mazowieckie, Poland Staff Paweł Maksimowski Wincenty Skupiński Wojciech Pawłowski Waldemar Tomaszewski …

Lanabecestat (formerly known as AZD3293 or LY3314814)

It’s only fair to share… Lanabecestat Molecular FormulaC26H28N4O Average mass412.527 Da Dispiro[cyclohexane-1,2′-[2H]indene-1′(3′H),2”-[2H]imidazol]-4”-amine, 4-methoxy-5”-methyl-6′-[5-(1-propyn-1-yl)-3-pyridinyl]-, (1α,1′R,4β)- (1r,1’R,4R)-4-Methoxy-5”-methyl-6′-[5-(1-propin-1-yl)-3-pyridinyl]-3’H-dispiro[cyclohexane-1,2‘-indene-1’,2”-imidazol]-4”-amin (1r,1’R,4R)-4-Methoxy-5”-methyl-6′-[5-(1-propyn-1-yl)-3-pyridinyl]-3’H-dispiro[cyclohexane-1,2‘-indene-1’,2”-imidazol]-4”-amine (lr,l’R,4R)- 4-methoxy-5″-methyl-6′-[5-(prop-l-yn-l-yl)pyridin-3-yl]-3’H- dispiro[cyclohexane-l,2′-inden-l’2′-imidazole]-4″-amine (lr,4r)-4-Methoxy-5″-methyl-6′-(5-prop-l-yn-l-ylpyridin-3-yl)-3’H-dispiro[cyclohexane- l,2′-indene-l’,2″-imidazol]- “-amine CAS 1383982-64-6 AZD3293 Dispiro[cyclohexane-1,2′-[1H]indene-1′(3’H),2”-[2H]imidazol]-4”-amine, 4-methoxy-5”-methyl-6‘-[5-(1-propyn-1-yl)-3-pyridinyl]-, (1‘R)- Lanabecestat LY3314814 UNII:X8SPJ492VF, AZ-12304146 Beta amyloid antagonist; Beta secretase 1 inhibitor; Beta secretase 2 inhibitor Fast Track (1α,1’R,4β)-4-Methoxy-5”-methyl-6′-[5-(1-propyn-1-yl)-3-pyridinyl]dispiro[cyclohexane-1,2′-[2H]indene-1′(3’H),2”-[2H]imidazol]-4”-amine (1,4-trans,1’R)-4-methoxy-5”-methyl-6′-[5-(prop-1-yn-1-yl)pyridin-3-yl]-3’H-dispiro[cyclohexane-1,2′-indene-1′,2”-imidazol]-4”-amine (1r,1’R,4R)-4-methoxy-5”-methyl-6′-[5-(prop-1-yn-1-yl)pyridin-3-yl]-3’H-dispiro[cyclohexane-1,2′-indene-1′,2”-imidazol]-4”-amine Lanabecestat (formerly known as AZD3293 or LY3314814) is …

Fe/ppm Cu nanoparticles as a recyclable catalyst for click reactions in water at room temperature

It’s only fair to share… Fe/ppm Cu nanoparticles as a recyclable catalyst for click reactions in water at room temperature Green Chem., 2017, 19,2506-2509 DOI: 10.1039/C7GC00883J, Communication Aurelien Adenot, Evan B. Landstrom, Fabrice Gallou, Bruce H. Lipshutz Nanomicelles housing a terminal alkyne and azide are delivered to ppm Cu-containing nanoparticles that catalyse click reactions in …

TILOGLIPTIN

It’s only fair to share… PRESENTING 2 MOLECULES………..I AM NOT SURE WHICH IS TITLE MOLECULE EMAIL ME amcrasto@gmail.com Molecular Formula: C25H27N7O Molecular Weight: 441.539 g/mol 2-[(3R)-3alpha-Aminopiperidino]-3-(2-butynyl)-5-(4-methyl-2-quinazolinylmethyl)-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidine-4-one CAS 1428445-40-2 REF Bioorganic & Medicinal Chemistry (2013), 21(7), 1749-1755.   NEXT ONE……………… CAS 1415912-31-0 1H-Purine-2,6-dione, 8-[(3R)-3-amino-1-piperidinyl]-7-(2-butyn-1-yl)-3,7-dihydro-3-methyl-1-([1,2,5]thiadiazolo[3,4-b]pyridin-5-ylmethyl)- 8-[(3R)-3-Amino-1-piperidinyl]-7-(2-butyn-1-yl)-3,7-dihydro-3-methyl-1-([1,2,5]thiadiazolo[3,4-b]pyridin-5-ylmethyl)-1H-purine-2,6-dione 8-[(3R)-3-aminopiperidin-1-yl]-7-but-2-ynyl-3-methyl-1-([1,2,5]thiadiazolo[3,4-b]pyridin-5-ylmethyl)purine-2,6-dione Molecular Formula: C21H23N9O2S Molecular Weight: 465.536 g/mol REF CN 102807568, CN 105315301,  WO 2016019868 Salt……….. CAS 1874255-95-4 C21 H23 N9 O2 …