It’s only fair to share… Trospium chloride CAS 47608-32-2 10405-02-4 WeightAverage: 392.518Monoisotopic: 392.22202025 Chemical FormulaC25H30NO3 T4Y8ORK057 FDA 2024, Cobenfy 9/26/2024, To treat schizophreniaPress ReleaseDrug Trials Snapshot Trospium chloride is a muscarinic antagonist used to treat overactive bladder.[3] It has side effects typical of this class of drugs, namely dry mouth, stomach upset, and constipation; these side effects cause problems with …
Tag «FDA 2024»
Flurpiridaz F 18
It’s only fair to share… Flurpiridaz F 18 WeightAverage: 367.84Monoisotopic: 367.1328329 Chemical FormulaC18H22ClFN2O3 2-tert-butyl-4-chloro-5-[[4-(2-(18F)fluoranylethoxymethyl)phenyl]methoxy]pyridazin-3-one FDA APPROVED 9/27/2024, Flyrcado, A radioactive diagnostic drug to evaluate for myocardial ischemia and infarction Flurpiridaz (18F), sold under the brand name Flyrcado, is a cyclotron-produced radioactive diagnostic agent for use with positron emission tomography (PET) myocardial perfusion imaging under rest or stress (pharmacologic or exercise).[3] Flurpiridaz (18F) It is given by intravenous …
Inavolisib
It’s only fair to share… Inavolisib WeightAverage: 407.378Monoisotopic: 407.140510438 Chemical FormulaC18H19F2N5O4 FDA APPROVED, 10/10/2024, Itovebi, To treat locally advanced or metastatic breast cancerDrug Trials Snapshot (2S)-2-[[2-[(4S)-4-(difluoromethyl)-2-oxo-1,3-oxazolidin-3-yl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl]amino]propanamide Inavolisib, sold under the brand name Itovebi, is an anti-cancer medication used for the treatment of breast cancer.[2][3] It is an inhibitor and degrader of mutant phosphatidylinositol 3-kinase (PI3K) alpha.[4] The PI3K-mediated signalling pathway has shown to …
Vanzacaftor
It’s only fair to share… Vanzacaftor FDA APPROVED vanzacaftor, tezacaftor, and deutivacaftor, 12/20/2024, Alyftrek , To treat cystic fibrosis (14S)-8-[3-(2-dispiro[2.0.24.13]heptan-7-ylethoxy)pyrazol-1-yl]-12,12-dimethyl-2,2-dioxo-2λ6-thia-3,9,11,18,23-pentazatetracyclo[17.3.1.111,14.05,10]tetracosa-1(22),5(10),6,8,19(23),20-hexaen-4-one 13H-17,20-Methano-8,12-nitrilo-12H-pyrido[3,2-d][1,2,6,13]thiatriazacyclooctadecin-5(6H)-one, 2-[3-(2-dispiro[2.0.2.1]hept-7-ylethoxy)-1H-pyrazol-1-yl]-14,15,16,17,18,19-hexahydro-19,19-dimethyl-, 7,7-dioxide, (17S)- (14S)-8-[3-(2-Dispiro[2.0.24.13]heptan-7-ylethoxy)pyrazol-1-yl]-12,12-dimethyl-2,2-dioxo-2?6-thia-3,9,11,18,23-pentazatetracyclo[17.3.1.111,14.05,10]tetracosa-1(22),5(10),6,8,19(23),20-hexaen-4-one (14S)-8-[3-(2-dispiro[2.0.24.13]heptan-7-ylethoxy)pyrazol-1-yl]-12,12-dimethyl-2,2-dioxo-2|E6-thia-3,9,11,18,23-pentazatetracyclo[17.3.1.111,14.05,10]tetracosa-1(22),5(10),6,8,19(23),20-hexaen-4-one Vanzacaftor (VX-121) is an orally active noval corrector of Cystic fibrosis transmembrane conductance regulator (CFTR). Vanzacaftor improves processing and trafficking of CFTR protein as well as increases chloride transport in triple combined …
Probenecid
It’s only fair to share… Probenecid 4-(dipropylsulfamoyl)benzoic acid C13H19NO4S, 285.359 FDA APPROVED, 10/25/2024, sulopenem etzadroxil, probenecid, Orlynvah, To treat uncomplicated urinary tract infections (uUTI)Drug Trial Snapshot Probenecid, also sold under the brand name Probalan, is a medication that increases uric acid excretion in the urine. It is primarily used in treating gout and hyperuricemia. Probenecid was developed as an alternative to caronamide[1] to …
Sulopenem
It’s only fair to share… Sulopenem (5R,6S)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(1R,3S)-1-oxothiolan-3-yl]sulfanyl-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid FDA APPROVED sulopenem etzadroxil, probenecid, 10/25/2024, To treat uncomplicated urinary tract infections (uUTI)Drug Trial Snapshot Sulopenem (CP-70,429) is a thiopenem antibiotic derivative from the penem family, which unlike most related drugs is orally active. It was developed in Japan in the 1990s, and has been approved to treat uncomplicated urinary tract infections …
Revumenib
It’s only fair to share… Revumenib FDA APPROVED 11/15/2024, Revuforj, To treat relapsed or refractory acute leukemia N-ethyl-2-[4-[7-[[4-(ethylsulfonylamino)cyclohexyl]methyl]-2,7-diazaspiro[3.5]nonan-2-yl]pyrimidin-5-yl]oxy-5-fluoro-N-propan-2-ylbenzamide Ingredient UNII CAS InChI Key Revumenib citrate YL4RYN734D 2761046-45-9 UBXFWTFPYATLBT-SGBGZXBGSA-N Revumenib sesquifumarate 75HI05N8HS 2169919-22-4 AXNUWYROYVRYIM-OQIJCFCCSA-N Revumenib, sold under the brand name Revuforj, is an anti-cancer medication used for the treatment of acute leukemias harboring lysine methyltransferase 2A gene (KMT2A) rearrangements.[1] It is designed to disrupt the …
Acoramidis
It’s only fair to share… Acoramidis 292.30 g/mol, C15H17FN2O3 3-[3-(3,5-dimethyl-1H-pyrazol-4-yl)propoxy]-4-fluorobenzoic acid FDA APPROVED 11/22/2024, Attruby To treat cardiomyopathy of wild-type or variant transthyretin-mediated amyloidosisDrug Trials Snapshot Ingredient UNII CAS InChI Key Acoramidis hydrochloride VY9C88C2NV 2242751-53-5 MGFZEARHINUOMX-UHFFFAOYSA-N Acoramidis, sold under the brand name Attruby, is a medication used for the treatment of cardiomyopathy.[1] It is a near-complete (>90%) transthyretin stabilizer, developed to mimic the …
Landiolol
It’s only fair to share… Landiolol FDA APPROVED 11/22/2024, Rapiblyk, To treat supraventricular tachycardia C25H39N3O8509.6 g/mol [(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl 3-[4-[(2S)-2-hydroxy-3-[2-(morpholine-4-carbonylamino)ethylamino]propoxy]phenyl]propanoate Landiolol, sold under the brand name Onoact among others, is a medication used for the treatment of tachycardia, atrial fibrillation, and atrial flutter.[1][4] It is a beta-adrenergic blocker;[4] an ultra short-acting, β1-superselective intravenous adrenergic antagonist, which decreases the heart rate effectively with less negative effect on …
Iomeprol
It’s only fair to share… Iomeprol WeightAverage: 777.089Monoisotopic: 776.8541 Chemical FormulaC17H22I3N3O8 FDA APPROVED, 11/27/2024, Iomervu, For use as a radiographic contrast agent 1-N,3-N-bis(2,3-dihydroxypropyl)-5-[(2-hydroxyacetyl)-methylamino]-2,4,6-triiodobenzene-1,3-dicarboxamide Iomeprol, sold under the brand name Imeron among others, is a medication used as a radiocontrast agent in X-ray imaging.[1][2][3] Iomeprol was approved for medical use in the United States in November 2024.[1][4][5] Experimental Properties Property Value Source melting …