It’s only fair to share… DEUCRAVACITINIB BMS-986165 CAS 1609392-27-9, C20H22N8O3, 425.46 6-(cyclopropanecarbonylamino)-4-[2-methoxy-3-(1-methyl-1,2,4-triazol-3-yl)anilino]-N-(trideuteriomethyl)pyridazine-3-carboxamide 6-(cyclopropanecarboxamido)-4-((2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl)amino)-N-(methyl-d3)pyridazine-3-carboxamide Tyk2-IN-4 UNII-N0A21N6RAU N0A21N6RAU GTPL10432 EX-A3154 BDBM50507816 NSC825520 s8879 OriginatorBristol-Myers Squibb ClassAmides; Aniline compounds; Anti-inflammatories; Antipsoriatics; Antirheumatics; Cyclopropanes; Ethers; Hepatoprotectants; Organic deuterium compounds; Pyridazines; Skin disorder therapies; Small molecules; Triazoles Mechanism of ActionTYK2 kinase inhibitors Phase IIIPlaque psoriasis Phase IICrohn’s disease; Lupus nephritis; Psoriatic arthritis; Systemic …
Tag «Systemic lupus erythematosus»
CEP 33779
It’s only fair to share… CEP-33779, CEP33779 CAS 1257704-57-6 Chemical Formula: C24H26N6O2S Molecular Weight: 462.57 Elemental Analysis: C, 62.32; H, 5.67; N, 18.17; O, 6.92; S, 6.93 N-(3-(4-methylpiperazin-1-yl)phenyl)-8-(4-(methylsulfonyl)phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine PRECLINICAL Treatment of Rheumatoid Arthritis, Agents for Colorectal Cancer Therapy Systemic Lupus Erythematosus, Jak2 Inhibitors Matthew A. Curry, Bruce D. Dorsey, Benjamin J. Dugan, Diane E. Gingrich, Eugen F. Mesaros, Karen L. …
ACT-334441, Cenerimod an S1P receptor 1 agonist
It’s only fair to share… ACT-334441 Cenerimod UNII-Y333RS1786; Y333RS1786 S1P receptor 1 agonist CAS 1262414-04-9 Chemical Formula: C25H31N3O5 Exact Mass: 453.22637 Actelion Pharmaceuticals Ltd. Martin Bolli, Cyrille Lescop, Boris Mathys,Keith Morrison, Claus Mueller, Oliver Nayler,Beat Steiner, (S)-3-(4-(5-(2-cyclopentyl-6-methoxypyridin-4-yl)-1,2,4-oxadiazol-3-yl)-2-ethyl-6-methylphenoxy)propane-1,2-diol (2S)-3-[4-[5-(2-cyclopentyl-6-methoxypyridin-4-yl)-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]propane-1,2-diol (S)-3-{4-[5-(2-Cyclopentyl-6-methoxy-pyridin-4-yl)-[1,2,4]oxadiazol-3-yl]-2-ethyl-6-methyl-phenoxy}-propane-1,2-diol Mechanism Of Action Sphingosine 1 phosphate receptor modulator Who Atc Codes L03A-X (Other immunostimulants) Ephmra Codes …