It’s only fair to share… Henagliflozin, SHR-3824 , CAS 1623804-44-3 C22-H24-Cl-F-O7, 454.8756 PHASE 2 for the treatment of type 2 diabetes China 20222, approvals 2022 HengRui (Originator) Jiangsu Hengrui Medicine Co Ltd UNII-21P2M98388; 21P2M98388; Henagliflozin; SHR3824; SHR-3824; HENAGLIFLOZIN PROLINE 4IO819SW6M 570.0 g/mol C27H33ClFNO9 (1R,2S,3S,4R,5R)-5-[4-chloro-3-[(4-ethoxy-3-fluorophenyl)methyl]phenyl]-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol;(2R)-pyrrolidine-2-carboxylic acid In April 2016, Jiangsu Hengrui Medicine is developing henagliflozin (phase 2 …
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Ebselen
It’s only fair to share… Ebselen 274.19 g/mol, C13H9NOSe 2-phenyl-1,2-benzoselenazol-3-one Ebselen is a benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase. It has a role as a neuroprotective agent, an apoptosis inducer, an anti-inflammatory drug, an antioxidant, a hepatoprotective agent, a genotoxin, a radical scavenger, an enzyme mimic, an EC 1.3.1.8 …
Sergliflozin Etabonate
It’s only fair to share… Sergliflozin Etabonate 408504-26-7 Cas no Ethyl [(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[2-[(4-methoxyphenyl)methyl]phenoxy]oxan-2-yl]methyl carbonate 2-(4-methoxybenzyl)phenyl 6-O-ethoxycarbonyl-beta-D-glucopyranosideethyl [(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[2-[(4-methoxyphenyl)methyl]phenoxy]tetrahydropyran-2-yl]methyl carbonateethyl [(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-{2-[(4-methoxyphenyl)methyl]phenoxy}oxan-2-yl]methyl carbonate PHASE 2……….TYPE 3 DIABETES AND OBESITYA SGLT-2 inhibitor potentially for the treatment of type 2 diabetes and obesity. GW-869682; GW-869682X; KGT-1251 MW 448.4, C23H28O9 KISSEI INNOVATORGSK DEVELOPER Sergliflozin Etabonate is a benzylphenol glucoside and selective sodium-glucose co-transporter …
Sparsentan
It’s only fair to share… Sparsentan (PS433540,RE-021) C32H40N4O5S Average mass592.749 FDA APPROVED 2023/2/17, Filspari 4′-((2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl)-N-(4,5-dimethylisoxazol-3-yl)-2′-(ethoxymethyl)-[1,1′-biphenyl]-2-sulfonamide 4′-[(2-Butyl-4-oxo-1.3-diazaspiro[4.41non-l-en-3-yl)methvn-N-(3,4- dimethyl-5-isoxazolyl)-2′-ethoxymethyl [ 1 , l’-biphenyll -2-sulfonamide SparsentanPS433540; RE-021, formerly known as DARACAS :254740-64-24-[(2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-N-(4,5- dimethylisoxazol-3-yl)-2-(ethoxymethyl)biphenyl-2-sulfonamideMechanism of Action:acting as both an Endothelin Receptor Antagonist (ERA) and Angiotensin Receptor Blocker (ARB).Indication: Focal Segmental Glomerulosclerosis (FSGS).Focal Segmental Glomerulosclerosis (FSGS) is a rare …
Donidalorsen
It’s only fair to share… Donidalorsen CAS 2304692-48-4 분자량 Mw 8672.64 화학식Mf C296H435N83O151P20S15 ISIS 721744, ISIS-721744 FDA 8/21/2025, Dawnzera, To prevent attacks of hereditary angioedema DNA, D((2′-O-(2-METHOXYETHYL))M5RU-SP-(2′-O-(2-METHOXYETHYL))RG-SP-(2′-O-(2-METHOXYETHYL))M5RC-(2′-O-(2-METHOXYETHYL))RA-(2′-O-(2-METHOXYETHYL))RA-SP-G-SP-T-SP-M5C-SP-T-SP-M5C-SP-T-SP-T-SP-G-SP-G-SP-M5C-SP-(2′-O-(2-METHOXYETHYL))RA-(2′-O-(2-METHOXYETHYL) Ingredient UNII CAS . Donidalorsen sodium Y30VEG5PH1 2304701-45-7 Donidalorsen, sold under the brand name Dawnzera, is a medication used to prevent attacks of hereditary angioedema.[1] Donidalorsen is a prekallikrein-directed antisense oligonucleotide.[1] It is given by injection under …
Baxdrostat
It’s only fair to share… Baxdrostat WeightAverage: 363.461Monoisotopic: 363.194677057 Chemical FormulaC22H25N3O2 N-[(8R)-4-(1-methyl-2-oxo-3,4-dihydroquinolin-6-yl)-5,6,7,8-tetrahydroisoquinolin-8-yl]propanamide Baxdrostat is an investigational drug that is being evaluated for the treatment of hypertension.[1] It is an aldosterone synthase inhibitor.[2][3] Baxdrostat is under investigation in clinical trial NCT06344104 (A Phase III Study to Investigate the Efficacy and Safety of Baxdrostat in Asian Participants With Uncontrolled Hypertension on Two or More …
Momelotinib
It’s only fair to share… Momelotinib 414.47, C23H22N6O2, 1056634-68-4 FDA 2023, Ojjaara, To treat intermediate or high-risk myelofibrosis in adults with anemiaDrug Trials Snapshot N-(Cyanomethyl)-4-[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]benzamide N-(Cyanomethyl)-4-[2-[4-(4-morpholinyl)phenylamino]pyrimidin-4-yl]benzamide Jak2 tyrosine kinase inhibitor; Jak1 tyrosine kinase inhibitor Inflammatory disease; Myelofibrosis; Myeloproliferative disorder; Pancreatic ductal adenocarcinoma; Polycythemia vera CYT 387; CYT-387; momelotinib) GS-0387 CYT387 sulfate saltCAS No: 1056636-06-6 CYT387 Mesylate CAS …
Linaprazan
It’s only fair to share… Linaprazan CHINA 2024, APPROVALS 2024, AstraZeneca, CINCLUS, GERD, linaprazan glurate, for the treatment of moderate to severe GERD, 8-[(2,6-dimethylphenyl)methylamino]-N-(2-hydroxyethyl)-2,3-dimethylimidazo[1,2-a]pyridine-6-carboxamide Chemical structure of linaprazan glurate CAS No.: 1228559-81-6 , X842 Molecular formula C26H32N4O5 Molecular weight 480.556086540222 Accurate quality 480.237 5-[2-[[8-[(2,6-dimethylphenyl)methylamino]-2,3-dimethylimidazo[1,2-a]pyridine-6-carbonyl]amino]ethoxy]-5-oxopentanoic acid Linaprazan is a lipophilic, weak base with potassium-competitive acid blocking (P-CAB) activity. …
Pradefovir
It’s only fair to share… Pradefovir WeightAverage: 423.79Monoisotopic: 423.0863188 Chemical FormulaC17H19ClN5O4P 9-[2-[[(2R,4S)-4-(3-chlorophenyl)-2-oxo-1,3,2λ5-dioxaphosphinan-2-yl]methoxy]ethyl]purin-6-amine 2R,4S-(+)-9-(2-(4-(3-chlorophenyl)-2-oxo-1,3,2-dioxaphosphorinan-2-yl)methoxyethyl)adenine HEPATITIS B VIRUS, APPROVALS 2024, CHINA 2024, Xi’an Xintong Pharmaceutical Research Co, Xinshumu Pradefovir Mesylate CAS No. : 625095-61-6, Remofovir mesylate 분자량 519.90 화학식 C18H23ClN5O7PS Pradefovir is a cyclodiester antiviral prodrug with specific activity against hepatitis B virus (HBV). Pradefovir is specifically metabolized …
Bevifibatide
It’s only fair to share… Bevifibatide Cas 710312-77-9 817.9 g/mol, C34H47N11O9S2 2-[(3S,6S,12S,20R,23S)-20-carbamoyl-12-[3-(diaminomethylideneamino)propyl]-3-(1H-indol-3-ylmethyl)-2,5,8,11,14,22-hexaoxo-17,18-dithia-1,4,7,10,13,21-hexazabicyclo[21.3.0]hexacosan-6-yl]acetic acid APPROVALS 2025, CHINA 2025, Bio-Thera Solutions, Beitaning RegisteredAcute coronary syndromes BAT-2094 | batifiban | Beitaning | Betagrin® | Compound I [CN101085809A] Bevifibatide is a synthetic cyclic heptapeptide, and its synthesis involves several stages of peptide chemistry. The primary methods used for producing peptides of this nature are solid-phase peptide synthesis (SPPS), …