It’s only fair to share… Asandeutertinib, Osimertinib-d3 CAS 1638281-46-5 N-[2-{2-(dimethylamino)ethylamino}-4-methoxy-5-({4-[1-(2H3)methyl-1H-indol-3-yl]pyrimidin-2-yl}amino)phenyl]prop-2-enamideepidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, antineoplastic MF C28H30. 2H3. N7O2, C28H30D3N7O2 MW 502.6 g/mol Asandeutertinib is an investigational new drug that is being evaluated for the treatment of cancer. It is an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) with antineoplastic properties.[1][2] Developed by TYK Medicines, this small molecule drug is currently …
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Admilparant
It’s only fair to share… Admilparant, (BMS-986278) CAS 2170126-74-4 MF C22H31N5O5 MW 445.5 g/mol (1S,3S)-3-({2-methyl-6-[1-methyl-5-({[methyl(propyl)carbamoyl]oxy}methyl)-1H-1,2,3-triazol-4-l]pyridin-3-yl}oxy)cyclohexane-1-carboxylic acidlysophosphatidic acid receptor 1 (LPA1) antagonist Admilparant is an investigational new drug being developed by Bristol-Myers Squibb for the treatment of idiopathic pulmonary fibrosis (IPF) and progressive pulmonary fibrosis (PPF). It is a first-in-class lysophosphatidic acid receptor 1 (LPA1) antagonist.[1][2] As of 2024, admilparant is in Phase III clinical trials …
Fexuprazan, Abeprazan
It’s only fair to share… Fexuprazan, Abeprazan; DWP14012; DWP-14012 1-[5-(2,4-difluorophenyl)-1-(3-fluorophenyl)sulfonyl-4-methoxypyrrol-3-yl]-N-methylmethanamine WeightAverage: 410.41Monoisotopic: 410.091198078 Chemical FormulaC19H17F3N2O3S Fexuprazan (trade name Fexuclue) is a drug for the treatment of gastroesophageal reflux disease (GERD).[1] It is a potassium-competitive acid blocker,[2] which is a class of drugs suppressing gastric acids.[3][4] Fexuprazan is approved for clinical use in South Korea,[4][5] Mexico,[6] Philippines,[7] Chile,[8] and Ecuador.[9] Abeprazan is under investigation in clinical trial …
Atigliflozin
It’s only fair to share… Atigliflozin CAS 647834-15-9 Chemical Formula: C18H22O7S Exact Mass: 382.1086 Molecular Weight: 382.43 AVE 2268; AVE-2268; AVE2268; Y0H7UPE4WJ (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-((2-(4-methoxybenzyl)thiophen-3-yl)oxy)tetrahydro-2H-pyran-3,4,5-triol Atigliflozin (AVE-2268) is an orally active and selective SGLT-2 inhibitor, with IC50s of 10 nM and 8.2 μM for hSGLT-2 and hSGLT-1) respectively. Atigliflozin can lower the blood glucose and improve the impaired oral glucose tolerance. …
Abarelix
It’s only fair to share… Abarelix CAS 183552-38-7 785804-17-3 (acetate) 183552-38-7 (free base) PPI149, PPI-149, PPI 149, R3827, R-3827, R 3827, Abarelix, Abarelix acetate, Plenaxis, W486SJ5824 Chemical Formula: C72H95ClN14O14 Exact Mass: 1414.6841 Molecular Weight: 1416.06 Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Nalpha-Me-Tyr]-D-Asn-Leu-ILys-Pro-DAla-NH2 (2R)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2R)-2-[[(2R)-2-acetamido-3-naphthalen-2-ylpropanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-3-pyridin-3-ylpropanoyl]amino]-3-hydroxypropanoyl]-methylamino]-3-(4-hydroxyphenyl)propanoyl]amino]-N-[(2S)-1-[[(2S)-1-[(2S)-2-[[(2R)-1-amino-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxo-6-(propan-2-ylamino)hexan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]butanediamide (2R)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2R)-2-[[(2R)-2-acetamido-3-naphthalen-2-ylpropanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-3-pyridin-3-ylpropanoyl]amino]-3-hydroxypropanoyl]-methylamino]-3-(4-hydroxyphenyl)propanoyl]amino]-N-[(2S)-1-[[(2S)-1-[(2S)-2-[[(2R)-1-amino-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxo-6-(propan-2-ylamino)hexan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]butanediamide Abarelix is a synthetic decapeptide and antagonist of naturally occurring gonadotropin-releasing hormone (GnRH). Abarelix directly and competitively binds to and blocks …
Rongliflozin, Olorigliflozin
It’s only fair to share… Rongliflozin Olorigliflozin, 6FP3NST6ZQ, DJT1116PG Cas 2035989-50-3 450.9 g/mol, C23H27ClO7 (1R,2S,3S,4R,5S)-5-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-1-[(1R)-1-hydroxyethyl]-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol Rongliflozin 화학구조 CAS No. : 2648020-91-9 MW 602.55 MF C23H27ClO7.C5H7NO3.5/4H2O Rongliflozin is an SGLT2 inhibitor developed as a potential treatment for diabetes.[1][2] Rongliflozin (DJT1116PG) is a selective and orally active inhibitor of sodium-glucose co-transporter-2 (SGLT-2). Rongliflozin can be used for the research of type 2 diabetes mellitus …
Mizagliflozin
It’s only fair to share… Mizagliflozin WeightAverage: 564.68Monoisotopic: 564.315914393 Chemical FormulaC28H44N4O8 2,2-dimethyl-3-[3-[3-methyl-4-[[5-propan-2-yl-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1H-pyrazol-4-yl]methyl]phenoxy]propylamino]propanamide Mizagliflozin is an SGLT1 inhibitor developed as a potential treatment for chronic constipation.[1][2] It progressed as far as Phase II trials in humans but was not approved for medical use, however it has since been investigated for other applications.[3][4] MIZAGLIFLOZIN is a small molecule drug with a maximum …
Henagliflozin
It’s only fair to share… Henagliflozin, SHR-3824 , CAS 1623804-44-3 C22-H24-Cl-F-O7, 454.8756 PHASE 2 for the treatment of type 2 diabetes China 20222, approvals 2022 HengRui (Originator) Jiangsu Hengrui Medicine Co Ltd UNII-21P2M98388; 21P2M98388; Henagliflozin; SHR3824; SHR-3824; HENAGLIFLOZIN PROLINE 4IO819SW6M 570.0 g/mol C27H33ClFNO9 (1R,2S,3S,4R,5R)-5-[4-chloro-3-[(4-ethoxy-3-fluorophenyl)methyl]phenyl]-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol;(2R)-pyrrolidine-2-carboxylic acid In April 2016, Jiangsu Hengrui Medicine is developing henagliflozin (phase 2 …
Ebselen
It’s only fair to share… Ebselen 274.19 g/mol, C13H9NOSe 2-phenyl-1,2-benzoselenazol-3-one Ebselen is a benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase. It has a role as a neuroprotective agent, an apoptosis inducer, an anti-inflammatory drug, an antioxidant, a hepatoprotective agent, a genotoxin, a radical scavenger, an enzyme mimic, an EC 1.3.1.8 …
Sergliflozin Etabonate
It’s only fair to share… Sergliflozin Etabonate 408504-26-7 Cas no Ethyl [(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[2-[(4-methoxyphenyl)methyl]phenoxy]oxan-2-yl]methyl carbonate 2-(4-methoxybenzyl)phenyl 6-O-ethoxycarbonyl-beta-D-glucopyranosideethyl [(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[2-[(4-methoxyphenyl)methyl]phenoxy]tetrahydropyran-2-yl]methyl carbonateethyl [(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-{2-[(4-methoxyphenyl)methyl]phenoxy}oxan-2-yl]methyl carbonate PHASE 2……….TYPE 3 DIABETES AND OBESITYA SGLT-2 inhibitor potentially for the treatment of type 2 diabetes and obesity. GW-869682; GW-869682X; KGT-1251 MW 448.4, C23H28O9 KISSEI INNOVATORGSK DEVELOPER Sergliflozin Etabonate is a benzylphenol glucoside and selective sodium-glucose co-transporter …