It’s only fair to share… Gemigliptin tartrate sesquihydrate; ゲミグリプチン Molecular Weight 666.47 Formula C18H19F8N5O2 • C4H6O6 • 1.5H2O 911637-19-9 (Gemigliptin); 1375415-82-9 (Gemigliptin L-tartrate Sesquihydrate) (3S)-3-amino-4-(5,5-difluoro-2-oxopiperidino)-1-[2,4-di(trifluoromethyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-7-yl]butan-1-one L-tartrate, sesquihydrate 1-{(2S)-2-Amino-4-[2,4-bis(trifluoromethyl)-5,8-dihydropyrido[3,4-d]pyrimidin-7(6H)-yl]-4-oxobutyl}-5,5-difluoro-2-piperidinone[ACD/IUPAC Name] 2-Piperidinone, 1-[(2S)-2-amino-4-[5,8-dihydro-2,4-bis(trifluoromethyl)pyrido[3,4-d]pyrimidin-7(6H)-yl]-4-oxobutyl]-5,5-difluoro- 5DHU18M5D6 911637-19-9 [RN] FREE FORM 9291 Gemigliptin gemigliptin tartarate gemigliptin(lc15-0444) LC15-0444 MFCD19443742 UNII:5DHU18M5D6 Gemiglo®; LC-150444; Zemiglo Gemigliptin L-tartrate sesquihydrate was approved by Korean food and Drug …
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Nalmefene hydrochloride dihydrate, ナルメフェン塩酸塩水和物 ,
It’s only fair to share… Nalmefene hydrochloride dihydrate, ナルメフェン塩酸塩水和物 2019/1/8, PMDA, JAPAN, Selincro, In January 2019, Otsuka received regulatory approval in Japan Antialcohol dependence, Narcotic antagonist, Opioid receptor partial agonist/antagonist Morphinan-3,14-diol, 17-(cyclopropylmethyl)-4,5-epoxy-6-methylene-, hydrochloride, hydrate (1:1:2), (5α)- Formula C21H25NO3. HCl. 2H2O CAS 1228646-70-5 5096-26-9 free form 58895-64-0 (Nalmefene HCl) Mol weight 411.9196 JF-1; NIH-10365; ORF-11676; SRD-174, Lu-AA36143 APPROVED 1995 USA Trade …
Esaxerenone エサキセレノン , эсаксеренон , إيساكسيرينون , 艾沙利 酮 ,
It’s only fair to share… Esaxerenone エサキセレノン , эсаксеренон , إيساكسيرينون , 艾沙利 酮 , CS-3150, XL-550 Formula C22H21F3N2O4S CAS 1632006-28-0 Mol weight 466.4734 Pmda approved japan, 2019/1/8, Minebro Antihypertensive, Aldosterone antagonist N62TGJ04A1 UNII:N62TGJ04A1 эсаксеренон [Russian] [INN] إيساكسيرينون [Arabic] [INN] 艾沙利酮 [Chinese] [INN] 1-(2-Hydroxyethyl)-4-methyl-N-[4-(methylsulfonyl)phenyl]-5-[2-(trifluoromethyl)phenyl]-1H-pyrrole-3-carboxamide 10230 1632006-28-0 [RN], 880780-76-7, 1072195-82-4 (+ isomer) 1072195-83-5 (- isomer) 1H-Pyrrole-3-carboxamide, 1-(2-hydroxyethyl)-4-methyl-N-[4-(methylsulfonyl)phenyl]-5-[2-(trifluoromethyl)phenyl]- Originator X-Ceptor Therapeutics Developer Daiichi Sankyo Company Class Antihyperglycaemics; Antihypertensives; Pyrroles; Small molecules; Sulfones Mechanism of Action Mineralocorticoid receptor antagonists …
Relugolix レルゴリクス
It’s only fair to share… Relugolix (TAK-385), RVT 601 レルゴリクス Formula C29H27F2N7O5S CAS 737789-87-6 Mol weight UNII 623.6304 UNII-P76B05O5V6 2019/1/8 PMDA JAPAN APPROVED, Relumina 1-{4-[1-(2,6-Difluorobenzyl)-5-[(dimethylamino)methyl]-3-(6-methoxy-3-pyridazinyl)-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-6-yl]phenyl}-3-methoxyurea Urea, N-[4-[1-[(2,6-difluorophenyl)methyl]-5-[(dimethylamino)methyl]-1,2,3,4-tetrahydro-3-(6-methoxy-3-pyridazinyl)-2,4-dioxothieno[2,3-d]pyrimidin-6-yl]phenyl]-N’-methoxy- 737789-87-6 [RN] 9628 P76B05O5V6 Originator Takeda Developer Myovant Sciences; Takeda; Takeda Oncology Class Analgesics; Antineoplastics; Ketones; Pyrimidines; Small molecules Mechanism of Action LHRH receptor antagonists Preregistration Uterine leiomyoma Phase III Pain; Prostate cancer No development reported Solid …
Metyrosine, Metirosine メチロシン метирозин , ميتيروسين , 甲酪氨酸 ,
It’s only fair to share… Metyrosine, Metirosine メチロシン метирозин , ميتيروسين , 甲酪氨酸 , Metyrosine (USP); Metirosine (JAN/INN); Demser (TN) CAS 672-87-7 Molecular FormulaC10H13NO3 Average mass195.215 Da APPROVED P[MDA JAPAN 2019/1/8 (-)-alpha-Methyl-L-tyrosine (–)-α-methyl-L-tyrosine (S)-alpha-Methyltyrosine Methyltyrosine Synthesis ReferenceUS2868818 α-Methyl-p-tyrosine метирозин [Russian] [INN] ميتيروسين [Arabic] [INN] 甲酪氨酸 [Chinese] [INN] (-)-(S)-2-Amino-3-(4-hydroxyphenyl)-2-methylpropionsaeure (-)-α-Methyl-L-tyrosine (2S)-2-amino-3-(4-hydroxyphenyl)-2-methylpropanoic acid 211-599-5 [EINECS] 3929 672-87-7 [RN] a-Methyl-3-(p-hydroxyphenyl)alanine a-methyl-L-tyrosine a-Methyl-p-tyrosine a-MPT Demser [Trade name] DOQ0J0TPF7 L 588357-0 L-2-Methyl-3-(4-hydroxyphenyl)alanine L-a-MT L-tyrosine, a-methyl- OPTICAL RoT -0.24 …
Omecamtiv mecarbil オメカムティブメカビル
It’s only fair to share… Omecamtiv mecarbil Molecular FormulaC20H24FN5O3 Average mass401.435 Da 4-[2-fluoro-3-[(6-methyl-3-pyridyl)carbamoylamino]benzyl]piperazine-1-carboxylic acid methyl ester AMG 423 AMG-423 CK1827452 CK-1827452; CK1827452 Cladribine [BAN] [INN] [JAN] [USAN] [Wiki] methyl 4-(2-fluoro-3-(3-(6-methylpyridin-3-yl)ureido)benzyl)piperazine-1-carboxylate 1-Piperazinecarboxylic acid, 4-[[2-fluoro-3-[[[(6-methyl-3-pyridinyl)amino]carbonyl]amino]phenyl]methyl]-, methyl ester 2M19539ERK オメカムティブメカビル 873697-71-3 [RN] 9088 Methyl 4-(2-fluoro-3-{[(6-methyl-3-pyridinyl)carbamoyl]amino}benzyl)-1-piperazinecarboxylate NMR https://file.selleckchem.com/downloads/nmr/S262301-CK-1827452-NMR-Selleck.pdf In January 2019, Cytokinetics and licensees Amgen and Servier are developing oral modified- and immediate-release formulations of the cardiac …
K-8986
It’s only fair to share… K-8986 (Z)-but-2-enedioic acid;7-[3-[4-[[1-(2-ethoxyethyl)benzimidazol-2-yl]methyl]piperazin-1-yl]propoxy]-4H-1,4-benzothiazin-3-one cas 1335112-55-4 mono maleate cas 1335112-57-6 di maleate cas 219741-69-2 free form C27 H35 N5 O3 S . C4 H4 O4 2H-1,4-Benzothiazin-3(4H)-one, 7-[3-[4-[[1-(2-ethoxyethyl)-1H-benzimidazol-2-yl]methyl]-1-piperazinyl]propoxy]-, (2Z)-2-butenedioate (1:1) 7-[3-[4-[[1-(2-Ethoxyethyl)benzimidazol-2-yl]methyl]-1-piperazinyl]propoxy]-3,4-dihydro-2H-1,4-benzothiazin-3-one monomaleate KOWA CO., LTD. 福田 友昭 FUKUDA, Tomoaki; JP 纐纈 章泰 KOKETSU, Akiyasu; JP 金児 佳生 KANEKO, Yoshio; JP 芦川 由香 ASHIKAWA, Yuka; JP Mono maleate 1H NMR (396 MHz, DMSO-d6) δ 1.03 (t, J = …
Ifetroban イフェトロバン
It’s only fair to share… Ifetroban イフェトロバン 3-[2-({(1S,2R,3S)-3-[4-(Pentylcarbamoyl)-1,3-oxazol-2-yl]-7-oxabicyclo[2.2.1]hept-2-yl}methyl)phenyl]propanoic acid Molecular FormulaC25H32N2O5 Average mass440.532 Da 143443-90-7; 3-[2-({(1S,2R,3S)-3-[4-(Pentylcarbamoyl)-1,3-oxazol-2-yl]-7-oxabicyclo[2.2.1]hept-2-yl}methyl)phenyl]propanoic acid Benzenepropanoic acid, 2-[[(1S,2R,3S)-3-[4-[(pentylamino)carbonyl]-2-oxazolyl]-7-oxabicyclo[2.2.1]hept-2-yl]methyl]- 3-[2-[[(1S,5S,6R)-5-[4-(pentylcarbamoyl)-1,3-oxazol-2-yl]-7-oxabicyclo[2.2.1]heptan-6-yl]methyl]phenyl]propanoic acid Benzenepropanoic acid, 2-((3-(4-((pentylamino)carbonyl)-2-oxazolyl)-7-oxabicyclo(2.2.1)hept-2-yl)methyl)-, (1S-(exo,exo))- BMS 180,291 BMS 180291-02 BMS180291 BMS 18029; BMS 180291; BMS 180291A; BMS-180291-02; Boxaban; CPI 211; Hepatoren; Portaban; Vasculan Ifetroban is a potent and selective thromboxane receptor antagonist.[1] Ifetroban has been used in …
Aceclofenac, ацеклофенак , أسيكلوفيناك , 醋氯芬酸 , アセクロフェナク
It’s only fair to share… Aceclofenac アセクロフェナク Molecular FormulaC16H13Cl2NO4 Average mass354.185 Da (2-{2-[(2,6-Dichlorophenyl)amino]phenyl}acetoxy)acetic acid [ACD/IUPAC Name] (2-{2-[(2,6-Dichlorphenyl)amino]phenyl}acetoxy)essigsäure [German] [ACD/IUPAC Name] 5608 89796-99-6 [RN] Aceclofenac [BAN] [INN] [JAN] [Wiki] acéclofénac [French] [INN] Aceclofenaco [Spanish] [INN] Aceclofenacum [Latin] [INN] Acide (2-{2-[(2,6-dichlorophényl)amino]phényl}acétoxy)acétique [French] [ACD/IUPAC Name] Benzeneacetic acid, 2-[(2,6-dichlorophenyl)amino]-, carboxymethyl ester [ACD/Index Name] RPK779R03H ацеклофенак[Russian][INN] أسيكلوفيناك[Arabic][INN] 醋氯芬酸[Chinese][INN] [({2-[(2,6-dichlorophenyl)amino]phenyl}acetyl)oxy]acetic acid [2-(2,6-Dichloro-phenylamino)-phenyl]-acetic acid carboxymethyl ester Aceclofenac CAS Registry Number: 89796-99-6 CAS Name: 2-[(2,6-Dichlorophenyl)amino]benzeneacetic acid carboxymethyl ester Additional Names: 2-[(2,6-dichlorophenyl)amino]phenylacetoxyacetic acid; glycolic acid [o-(2,6-dichloroanilino)phenyl]acetate …
Diclofenac Sodium
It’s only fair to share… Diclofenac Sodium 15307-79-6; Sodium diclofenac; Diclofenac sodium salt; Voltaren; Solaraze Molecular Formula: C14H10Cl2NNaO2 Molecular Weight: 318.129 g/mol Diclofenac, sold under the trade names Voltaren among others, is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammatory diseases such as gout.[3] It is taken by mouth or applied to the skin.[3] Improvements in pain typically occur within …