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Zoledronic acid

Zoledronic acid CGP-42446, ZOL-446 ATC:M05BA08 Use:antineoplastic, bone resorption inhibitor, biphosphonate Chemical name:[1-hydroxy-2-(1H-imidazol-1-yl)ethylidene]bis[phosphonic acid] Formula:C5H10N2O7P2 MW:272.09 g/mol CAS-RN:118072-93-8 Derivatives Disodium salt tetrahydrate Formula:C5H8N2Na2O7P2 • 4H2O MW:388.11 g/mol CAS-RN:165800-07-7 Trisodium salt hydrate Formula:C5H7N2Na3O7P2 • 2/5H2O MW:1726.21 g/mol CAS-RN:165800-08-8 Zoledronic Acid CAS Registry Number: 118072-93-8; 165800-06-6 (monohydrate) CAS Name: [1-Hydroxy-2-(1H-imidazol-1-yl)ethylidene]bisphosphonic acid Additional Names: 2-(imidazol-1-yl)-1-hydroxyethane-1,1-diphosphonic acid Manufacturers’ Codes: CGP-42446 Trademarks: Zometa (Novartis) Molecular Formula: C5H10N2O7P2 Molecular Weight: 272.09 …

Arterolane Maleate

Arteolane Maleate C26H40N2O8 Molecular Weight: 508.612 CAS 959520-73-1 664338-39-0 (free base) 959520-73-1 (maleate) 959520-79-7 (acetate) 664338-40-3 (tosylate) 959520-82-2 (tartrate) 959520-83-3 (citrate) N-(2-amino-2-methylpropyl)-2-((1R,3R,4”S,5R,5’s,7R)-dispiro[adamantane-2,3′-[1,2,4]trioxolane-5′,1”-cyclohexan]-4”-yl)acetamide maleate Dispiro[cyclohexane-1,3′-[1,2,4]trioxolane-5′,2”-tricyclo[3.3.1.13,7]decane]-4-acetamide, N-(2-amino-2-methylpropyl)-, cis-, (2Z)-2-butenedioate (1:1) APPROVED 4.11.2017 CDSCO Arteolane Maleate and Piperaquine phosphate Dispersible tablets (37.5 mg +187.5 mg Indicated in children aged 6 months to 12 years for the treatment …

Bepotastine Besilate, ベポタスチンベシル酸塩

Bepotastine Besilate ベポタスチンベシル酸塩 Molecular FormulaC27H31ClN2O6S Average mass547.063 Da UNII:6W18MO1QR3 (+)-(S)-4-(4-((4-Chlorophenyl)(2-pyridyl)methoxy)piperidino)butyric acid monobenzenesulfonate (S)-4-(4-((4-chlorophenyl)(pyridin-2-yl)methoxy)piperidin-1-yl)butanoic acid compound with benzenesulfonic acid (1:1) 190786-44-8 [RN] 125602-71-3 FREE FORM, UNII: 6W18MO1QR3 1-Piperidinebutanoic acid, 4-[(S)-(4-chlorophenyl)-2-pyridinylmethoxy]-, benzenesulfonate (1:1) [ACD/Index Name] 4-{4-[(S)-(4-Chlorophenyl)(2-pyridinyl)methoxy]-1-piperidinyl}butanoic acid benzenesulfonate (1:1) Talion [Trade name] tau284 TAU-284DS, TAU-284 DA-5206 HL-151 SNJ-1773 Use:antiallergic, antihistaminic For the symptomatic treatment of itchy eyes (caused by IgE-induced mast cell degranulation) …

FIRSOCOSTAT, ND 630, GS-0976, NDI-010976

FIRSOCOSTAT, ND 630, NDI 010976, ND-630, NDI-010976 CAS: 1434635-54-7, UNII: XE10NJQ95M PHASE 2, Non-alcoholic steatohepatitis, GILEAD 1,4-dihydro-1-[(2R)-2-(2-methoxyphenyl)-2-[(tetrahydro-2H-pyran-4-yl)oxy]ethyl]-α,α,5-trimethyl-6-(2-oxazolyl)-2,4-dioxo-thieno[2,3-d]pyrimidine-3(2H)-acetic acid 2-[l-[2-(2-methoxyphenyl)-2-(oxan-4-yloxy)ethyl]-5- methyl-6-(l,3-oxazol-2-yl)-2,4-dioxo-lH,2H,3H,4H-thieno[2,3-d]pyrimidin-3-yl]-2- methylpropanoic acid 2-[1-[(2R)-2-(2-methoxyphenyl)-2-(oxan-4-yloxy)ethyl]-5-methyl-6-(1,3-oxazol-2-yl)-2,4-dioxothieno[2,3-d]pyrimidin-3-yl]-2-methylpropanoic acid CAS 1434635-54-7 Thieno[2,3-d]pyrimidine-3(2H)-acetic acid, 1,4-dihydro-1-[(2R)-2-(2-methoxyphenyl)-2-[(tetrahydro-2H-pyran-4-yl)oxy]ethyl]-α,α,5-trimethyl-6-(2-oxazolyl)-2,4-dioxo- Molecular Formula: C28H31N3O8S Molecular Weight: 569.62604 g/mol Company Nimbus Therapeutics LLC Description Small molecule allosteric inhibitor of acetyl-coenzyme A carboxylase alpha (ACACA; ACC1) and acetyl-coenzyme A carboxylase beta (ACACB; ACC2) …

Lanadelumab, ラナデルマブ

(Heavy chain) EVQLLESGGG LVQPGGSLRL SCAASGFTFS HYIMMWVRQA PGKGLEWVSG IYSSGGITVY ADSVKGRFTI SRDNSKNTLY LQMNSLRAED TAVYYCAYRR IGVPRRDEFD IWGQGTMVTV SSASTKGPSV FPLAPSSKST SGGTAALGCL VKDYFPEPVT VSWNSGALTS GVHTFPAVLQ SSGLYSLSSV VTVPSSSLGT QTYICNVNHK PSNTKVDKRV EPKSCDKTHT CPPCPAPELL GGPSVFLFPP KPKDTLMISR TPEVTCVVVD VSHEDPEVKF NWYVDGVEVH NAKTKPREEQ YNSTYRVVSV LTVLHQDWLN GKEYKCKVSN KALPAPIEKT ISKAKGQPRE PQVYTLPPSR EEMTKNQVSL TCLVKGFYPS DIAVEWESNG QPENNYKTTP PVLDSDGSFF LYSKLTVDKS RWQQGNVFSC SVMHEALHNH YTQKSLSLSP G (Light chain) DIQMTQSPST LSASVGDRVT ITCRASQSIS SWLAWYQQKP …

Sodium zirconium cyclosilicate, ナトリウムジルコニウムシクロケイ酸塩

Sodium zirconium cyclosilicate ZS-9, ZS 9, UZSi-9 CAS 242800-27-7, H2 O3 Si . x H2 O . 2/3 Na . 1/3 Zr, Sodium zirconium cyclosilicate; Silicic acid (H2SiO3), Sodium zirconium(4+) salt (3:2:1), hydrate USAN CAS 17141-74-1, H6 O9 Si3 . 2 Na . Zr, Silicic acid (H2SiO3), sodium zirconium(4+) salt (3:2:1), hydrate, Sodium zirconium silicate (Na2ZrSi3O9) hydrate ナトリウムジルコニウムシクロケイ酸塩 ZrH4O6. 3H4SiO4. 2H2O. 2Na, 561.6068, AS IN kegg Molecular Formula, H6-O9-Si3.2Na.Z, Molecular Weight, 371.5004 …

Glycopyrronium bromide, гликопиррония бромид , بروميد غليكوبيرونيوم , 格隆溴铵 , グリコピロニウム臭化物

Glycopyrronium bromide гликопиррония бромид [Russian] [INN] بروميد غليكوبيرونيوم [Arabic] [INN] 格隆溴铵 [Chinese] [INN] グリコピロニウム臭化物 Cas 596-51-0, 3-Hydroxy-1,1-dimethylpyrrolidinium bromide α-cyclopentylmandelate (6CI,7CI) Pyrrolidinium, 3-[(cyclopentylhydroxyphenylacetyl)oxy]-1,1-dimethyl-, bromide (9CI) Pyrrolidinium, 3-hydroxy-1,1-dimethyl-, bromide, α-cyclopentylmandelate (8CI) 1,1-Dimethyl-3-hydroxypyrrolidinium bromide α-cyclopentylmandelate AHR-504 Asecryl Copyrrolate Gastrodyn Glycopyrrolate Glycopyrrolate bromide Glycopyrrone bromide Glycopyrronium bromide NSC 250836 NSC 251251 NSC 251252 NVA 237 Nodapton Robanul Robinul Seebri Tarodyl Tarodyn β-1-Methyl-3-pyrrolidyl-α-cyclopentylmandelate methobromide CAS FREE …

Vericiguat, ベルイシグアト

Vericiguat BAY 102; BAY-1021189; MK-1242 1350653-20-1 Chemical Formula: C19H16F2N8O2 Molecular Weight: 426.3878 Vericiguat; 1350653-20-1; UNII-LV66ADM269; Methyl (4,6-diamino-2-(5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-5-yl)carbamate; BAY-1021189; LV66ADM269 Methyl (4,6-diamino-2-(5-fluoro-1-((2-fluorophenyl)methyl)-1H-pyrazolo(3,4-b)pyridin-3-yl(pyrimidin-5-yl)carbamate methyl N-[4,6-diamino-2-[5-fluoro-1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl]carbamate Methyl{4,6-diamino-2-[5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridi- n-3-yl]pyrimidin-5-yl}carbamate Originator Bayer HealthCare Pharmaceuticals Developer Bayer HealthCare Pharmaceuticals; Merck & Co Mechanism of Action Guanylate cyclase stimulants Phase III Chronic heart failure Phase I Coronary artery disease 28 May 2018 Phase II VITALITY HFpEF trial for …

Ferric Maltol, マルトール第二鉄

Ferric Maltol Iron, tris(3-hydroxy-2-methyl-4H-pyran-4-onato-O3,O4)- Molecular Formula: C18H15FeO9 Molecular Weight: 431.154 g/mol iron(3+);2-methyl-4-oxopyran-3-olate RN: 33725-54-1 UNII: MA10QYF1Z0 Feraccru Ferric maltol; UNII-MA10QYF1Z0; MA10QYF1Z0; Ferric maltol (INN); Ferric maltol [INN]; 33725-54-1 Shield Therapeutics, under license from Vitra Pharmaceuticals UPDATE Originator University of Cambridge; University of London Developer Shield Therapeutics Class Antianaemics; Ferric compounds; Pyrones; Small molecules Mechanism of Action Iron replacements Marketed Iron deficiency anaemia …

Daprodustat, ダプロデュスタット

Daprodustat, GSK1278863 ダプロデュスタット CAS 960539-70-2 GSK1278863; GSK 1278863; GSK-1278863; Daprodustat C19H27N3O6 Exact Mass: 393.18999 (1,3-dicyclohexyl-2,4,6-trioxohexahydropyrimidine-5-carbonyl)glycine N-[(l,3-dicyclohexyl-6-hydroxy-2,4-dioxo-l,2,3,4- tetrahydro-5-pyrimidinyl)carbonyl]glycine 2-(1,3-dicyclohexyl-2,4,6-triohexahydropyrimidine-5-carboxamide acetic acid Mechanism of Action: HIF-prolyl hydroxylase inhibitor Indication: anemia, diabetic wounds, and reduction of ischemic complications Development Stage: Phase II Developer:GlaxoSmithKline UNII:JVR38ZM64B ダプロデュスタット Daprodustat C19H27N3O6 : 393.43 [960539-70-2] Daprodustat , also known as GSK1278863, is a novel HIF-prolyl …