It’s only fair to share… ABT-737 Molecular Weight 813.43 Formula C42H45ClN6O5S2 CAS No. 852808-04-9 ABT-737 is a small molecule drug that inhibits Bcl-2 and Bcl-xL, two members of the Bcl-2 family of evolutionarily-conserved proteins that share Bcl-2 Homology (BH) domains. First developed as a potential cancer chemotherapy,[1] it was subsequently identified as a senolytic (a drug that selectively induces cell death in senescent cells).[2] The Bcl-2 family is most notable for their regulation of apoptosis, a form …