It’s only fair to share… .HCl Melphalan flufenamide hydrochloride メルファランフルフェナミド塩酸塩; L-Phenylalanine, 4-[bis(2-chloroethyl)amino]-L-phenylalanyl-4-fluoro-, ethyl ester, hydrochloride Formula C24H30Cl2FN3O3. HCl CAS 380449-54-7 Mol weight 534.8786 FDA APPROVED PEPAXTO, 2021/2/26 Efficacy Antineoplastic, Alkylating agent Disease Multiple myeloma Ethyl (2S)-2-[(2S)-2-amino-3-{4-[bis(2-chloroethyl)amino]phenyl}propanamido]-3-(4-fluorophenyl)propanoate J 1 J 1 (prodrug) L-Melphalanyl-L-p-fluorophenylalanine ethyl ester Melflufen Melphalan flufenamide Pepaxto Prodrug J 1 Melflufen Molecular FormulaC24H30Cl2FN3O3 Average …
Category «Uncategorized»
AZD1222 (ChAdOx1), Oxford–AstraZeneca COVID-19 vaccine, COVISHIELD
It’s only fair to share… AZD1222 (ChAdOx1) Identifiers CAS Number 2420395-83-9 ChAdOx1 nCoV- 19 Corona Virus Vaccine (Recombinant) COVISHIELD™ DNA (recombinant simian adenovirus Ox1 ΔE1E3 vector human cytomegalovirus promoter plus human tissue plasminogen activator signal peptide fusion protein with severe acute respiratory syndrome coronavirus 2 isolate Wuhan-Hu-1 spike glycoprotein codon optimized-specifying) The University of Oxford, AstraZeneca …
Pyridostigmine
It’s only fair to share… Pyridostigmine Molecular FormulaC9H13N2O2 Average mass181.211 Da 155-97-5 [RN] 3-[(Dimethylcarbamoyl)oxy]-1-methylpyridinium 3-Dimethylcarbamoyloxy-1-methyl-pyridinium 5-21-02-00078 (Beilstein Handbook Reference) [Beilstein] Pyridostigmine Bromide CAS Registry Number: 101-26-8 CAS Name: 3-[[(Dimethylamino)carbonyl]oxy]-1-methylpyridinium bromide Additional Names: 3-hydroxy-1-methylpyridinium bromide dimethylcarbamate; 1-methyl-3-hydroxypyridinium bromide dimethylcarbamate; 3-(dimethylcarbamyloxy)-1-methylpyridinium bromide Manufacturers’ Codes: Ro-1-5130 Trademarks: Kalymin (Temmler); Mestinon (Roche); Regonol (Organon) Molecular Formula: C9H13BrN2O2 Molecular Weight: 261.12 Percent Composition: C 41.40%, H 5.02%, Br 30.60%, N …
Buspirone
It’s only fair to share… Buspirone Molecular FormulaC21H31N5O2 Average mass385.503 Da буспирон بوسبيرون 丁螺酮 251-489-4 [EINECS] 253-072-2 [EINECS] 36505-84-7 [RN] 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione 8-[4-[4-(2-Pyrimidinyl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione 8-[4-[4-(2-Pyrimidinyl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione Buspin Buspirone Spitomin Buspirone CAS Registry Number: 36505-84-7 CAS Name: 8-[4-[4-(2-Pyrimidinyl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione Molecular Formula: C21H31N5O2 Molecular Weight: 385.50 Percent Composition: C 65.43%, H 8.11%, N 18.17%, O 8.30% Literature References: Non-benzodiazepine anxiolytic; 5-hydroxytryptamine (5-HT1) receptor agonist. Prepn: Y. H. Wu et al., J. …
Azelnidipine
It’s only fair to share… Azelnidipine C33H34N4O6, 582.6 g/mol CAS 123524-52-7 3-(1-Benzhydrylazetidin-3-yl) 5-isopropyl 2-amino-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate CS-905, RS-9054 3,5-PYRIDINEDICARBOXYLIC ACID, 2-AMINO-1,4-DIHYDRO-6-METHYL-4-(3-NITROPHENYL)-, 3-[1-(DIPHENYLMETHYL)-3-AZETIDINYL] 5-(1-METHYLETHYL) ESTER Approved India cdsco 2020 SYN REF https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245158/ MP 95-98 °C AND NMR WO 2004058745 . EP 266922 Azelnidipine is a dihydropyridine calcium channel blocker. It is marketed by Daiichi-Sankyo pharmaceuticals, Inc. in Japan. It has a gradual onset of action …
EVEROLIMUS
It’s only fair to share… Everolimus 159351-69-6 [RN] 23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone, 9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-(2-hydr oxyethoxy)-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-, (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,26R,27R,34aS)- 23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone, 9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-, (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)- 42-O-(2-Hydroxyethyl)rapamycin Synonyms:RAD-001, SDZ-RAD, Afinitor ATC:L04AA18 Use:immunosuppressant Chemical name:42-O-(2-hydroxyethyl)rapamycin Formula:C53H83NO14 MW:958.24 g/mol CAS-RN:159351-69-6 Everolimus CAS Registry Number: 159351-69-6 CAS Name: 42-O-(2-Hydroxyethyl)rapamycin Additional Names: 40-O-(2-hydroxyethyl)rapamycin Manufacturers’ Codes: RAD-001; SDZ RAD Trademarks: Certican (Novartis) Molecular Formula: C53H83NO14 Molecular Weight: 958.22 Percent Composition: C 66.43%, H 8.73%, N 1.46%, O 23.38% Literature References: Macrolide immunosuppressant; …
DETOMIDINE
It’s only fair to share… DETOMIDINE 1H-Imidazole, 4-[(2,3-dimethylphenyl)methyl]- 4-(2,3-Dimethylbenzyl)-1H-imidazole 5078 76631-46-4 [RN] 7N8K34P2XH Molecular FormulaC12H14N2 Average mass186.253 Da UNII-7N8K34P2XH детомидин ديتوميدين 地托咪定 Formal Name 5-[(2,3-dimethylphenyl)methyl]-1H-imidazole, monohydrochloride CAS Number 90038-01-0 Synonyms Domosedan MPV 253AII Molecular Formula C12H14N2 • HCl Formula Weight 222.7 Detomidine CAS Registry Number: 76631-46-4 CAS Name: 4-[(2,3-Dimethylphenyl)methyl]-1H-imidazole Additional Names: 4-(2¢,3¢-dimethylbenzyl)imidazole Molecular Formula: C12H14N2 Molecular Weight: 186.25 Percent Composition: C 77.38%, …
Fenfluramine Hydrochloride
It’s only fair to share… Fenfluramine DEA No. 1670 S 768 2020/12/18, FDA APPROVED, Fintepla Fenfluramine hydrochloride Formula C12H16F3N. HCl CAS 404-82-0 458-24-2 (FREE) Mol weight 267.7183 Antiobesity Efficacy Appetite suppressant Disease Dravet syndrome (+-)-Fenfluramine chloride (+-)-Fenfluramine hydrochloride Racemic fenfluramine hydrochloride Fenfluramine hydrochloride [USAN] AHR 3002 EINECS 206-968-2 1-(m-Trifluoromethylphenyl)-2-(ethylamino)propane hydrochloride AHR-3002 Research Code：ZX-008 MOA：Serotonin agonist …
Fluvoxamine
It’s only fair to share… Fluvoxamine Molecular FormulaC15H21F3N2O2 Average mass318.335 Da 54739-18-3 (E)-5-Methoxy-1-[4-(trifluoromethyl)phenyl]-1-pentanone O-(2-Aminoethyl)oxime 1-Pentanone, 5-methoxy-1-[4-(trifluoromethyl)phenyl]-, O-(2-aminoethyl)oxime, (1E)- 2-[({(1E)-5-Methoxy-1-[4-(trifluoromethyl)phenyl]pentylidene}amino)oxy]ethanamine 2-{[(E)-{5-Methoxy-1-[4-(trifluoromethyl)phenyl]pentylidene}amino]oxy}ethanamine 1-Pentanone, 5-methoxy-1-(4-(trifluoromethyl)phenyl)-, O-(2-aminoethyl)oxime, (E)- 3879 54739-18-3 [RN] 5583954 [Beilstein] 5-Methoxy-4′-(trifluoromethyl)valerophenone (E)-O-(2-aminoethyl)oxime A selective serotonin reuptake inhibitor that is used in the treatment of DEPRESSION and a variety of ANXIETY DISORDERS. Fluvoxamine, sold under the brand name Luvox among others, …
Evinacumab
It’s only fair to share… (Heavy chain) EVQLVESGGG VIQPGGSLRL SCAASGFTFD DYAMNWVRQG PGKGLEWVSA ISGDGGSTYY ADSVKGRFTI SRDNSKNSLY LQMNSLRAED TAFFYCAKDL RNTIFGVVIP DAFDIWGQGT MVTVSSASTK GPSVFPLAPC SRSTSESTAA LGCLVKDYFP EPVTVSWNSG ALTSGVHTFP AVLQSSGLYS LSSVVTVPSS SLGTKTYTCN VDHKPSNTKV DKRVESKYGP PCPPCPAPEF LGGPSVFLFP PKPKDTLMIS RTPEVTCVVV DVSQEDPEVQ FNWYVDGVEV HNAKTKPREE QFNSTYRVVS VLTVLHQDWL NGKEYKCKVS NKGLPSSIEK TISKAKGQPR EPQVYTLPPS QEEMTKNQVS LTCLVKGFYP SDIAVEWESN GQPENNYKTT PPVLDSDGSF FLYSRLTVDK SRWQEGNVFS CSVMHEALHN HYTQKSLSLS LGK (Light chain) …