It’s only fair to share… Umbralisib tosylate Formula C31H24F3N5O3. C7H8O3S Cas 1532533-72-4 FREE 1532533-67-7 Mol weight 743.7508 FDA APPR 2021/2/5 ウムブラリシブトシル酸塩; Treatment of cancer and B-cell related disorders Antineoplastic RP-5152; RP-5237; PI3K delta inhibitors (cancer), Rhizen/Incozen; PI3K delta inhibitors (B-cell lymphoma/hematological cancers), Incozen/Rhizen; TGR-1202; TG-1202; RV-1001; umbralisib tosylate; umbralisib; RP-5264; RP-5307; dual PI3Kdelta/CK1 inhibitor (cancer), TG Therapeutics; …
Category «Uncategorized»
Amiodarone
It’s only fair to share… Amiodarone CAS : 1951-25-3 (2-Butyl-3-benzofuranyl)[4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]methanone 2-butyl-3-benzofuranyl-4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl ketone; 2-butyl-3-[3,5-diiodo-4-(b-diethylaminoethoxy)benzoyl]benzofuran Molecular Formula: C25H29I2NO3 Molecular Weight: 645.31 Percent Composition: C 46.53%, H 4.53%, I 39.33%, N 2.17%, O 7.44% In December 1985, amiodarone was approved by the FDA for the treatment of arrhythmias.[6] This makes amiodarone one of the few drugs approved by …
TROFINETIDE
It’s only fair to share… Trofinetide Molecular FormulaC13H21N3O6 Average mass315.322 Da Tofinetide , NNZ-2566 10076 853400-76-7 [RN] glycyl-2-methyl-L-prolyl-L-glutamic acid H-Gly-PMe-Glu-OH L-Glutamic acid, glycyl-2-methyl-L-prolyl- UNII-Z2ME8F52QL Z2ME8F52QL трофинетид [Russian] [INN] تروفينيتيد [Arabic] [INN] 曲非奈肽 [Chinese] [INN] IUPAC Condensed H-Gly-aMePro-Glu-OH Sequence GXE HELM PEPTIDE1{G.[*C(=O)[C@@]1(CCCN1*)C |$_R2;;;;;;;;_R1;$|].E}$$$$ IUPAC glycyl-alpha-methyl-L-prolyl-L-glutamic acid An (1-3) IGF-1 analog with neuroprotective activity. OPTICAL ROT; -52.4 ° Conc: 0.19 g/100mL; water …
IMRECOXIB
It’s only fair to share… Imrecoxib (Hengyang) CHINA 2012 osteoarthritis 2H-Pyrrol-2-one, 1,5-dihydro-3-(4-methylphenyl)-4-[4-(methylsulfonyl)phenyl]-1-propyl- 3-(4-Methylphenyl)-4-[4-(methylsulfonyl)phenyl]-1-propyl-1,5-dihydro-2H-pyrrol-2-one 395683-14-4 [RN] Imrecoxib was approved by China Food and Drug Administration (CFDA) on May 20, 2011. It was developed and marketed as 恒扬® by HengRui Pharmaceuticals. Imrecoxib is a selective COX-2 inhibitor indicated for treatment of osteoarthritis. 恒扬® is available as tablet for …
Telacebec
It’s only fair to share… Telacebec Molecular FormulaC29H28ClF3N4O2 Average mass557.006 Da Telacebec, IAP6, CAS No. 1334719-95-7 телацебек [Russian] [INN] تيلاسيبيك [Arabic] [INN] 特雷贝克 10573 1334719-95-7 [RN] 55G92WGH3X 6-Chloro-2-ethyl-N-(4-{4-[4-(trifluoromethoxy)phenyl]-1-piperidinyl}benzyl)imidazo[1,2-a]pyridine-3-carboxamide Imidazo[1,2-a]pyridine-3-carboxamide, 6-chloro-2-ethyl-N-[[4-[4-[4-(trifluoromethoxy)phenyl]-1-piperidinyl]phenyl]methyl]- Q203 Q-203 T56 AN DNJ C2 HG BVM1R D- AT6NTJ DR DOXFFF Qurient Therapeutics and Russia licensee Infectex are developing telacebec, an oral formulation which targets QcrB subunit of the cytochrome …
IGURATIMOD
It’s only fair to share… Iguratimod Molecular FormulaC17H14N2O6S Average mass374.368 Da UNII-4IHY34Y2NV игуратимод إيغوراتيمود 艾拉莫德 123663-49-0 [RN] 3-Formylamino-7-methylsulfonylamino-6-phenoxy-4H-1-benzopyran-4-one 4IHY34Y2NV 8176 IGU Methanesulfonamide, N-[3-(formylamino)-4-oxo-6-phenoxy-4H-1-benzopyran-7-yl]- N-(3-Formamido-4-oxo-6-phenoxy-4H-chromen-7-yl)methanesulfonamide product patent US4954518 Research Code： T-614 Trade Name： Iremod® / Kolbet® / Careram® MOA： Nuclear factor NF-κB activation inhibitor Indication： Rheumatoid arthritis Status： Approved Company： Simcere (Originator) , Taisho Toyama,Eisai Sales： ATC Code： Approved Countries or Area JP …
RIDINILAZOLE
It’s only fair to share… RIDINILAZOLE SMT19969 Molecular FormulaC24H16N6 Average mass388.424 Da ридинилазол [Russian] [INN] ريدينيلازول [Arabic] [INN] 利地利唑 [Chinese] [INN] リジニラゾール; 10075 2,2′-Di(4-pyridinyl)-3H,3’H-5,5′-bibenzimidazole 308362-25-6 [RN] 6,6′-Bi-1H-benzimidazole, 2,2′-di-4-pyridinyl- Summit Therapeutics (formerly Summit Corp ) is developing ridinilazole the lead compound from oral narrow-spectrum, GI-restricted antibiotics, which also include SMT-21829, for the treatment of Clostridium difficile infection and prevention of recurrent disease. …
OI 338
It’s only fair to share… OI 338 OI338GT (NN1953) NNC0123-0000-0338 Insulin oral (NN 1953); Insulin-338-GIPET-I; LAI 338; NN 1438; NN-1953; NNC-0123-0000-0338; NNC0123-0338; OI-338GT; Oral insulin 338 C10 OriginatorNovo Nordisk ClassAntihyperglycaemics; Insulins; Pancreatic hormones Mechanism of ActionOrnithine decarboxylase stimulants; Phosphokinase stimulants; Protein tyrosine kinase stimulants Phase IIType 1 diabetes mellitus; Type 2 diabetes mellitus 28 Jul …
Fosnetupitant
It’s only fair to share… Fosnetupitant Molecular FormulaC31H35F6N4O5P Average mass688.598 Da [4-[5-[[2-[3,5-bis(trifluoromethyl)phenyl]-2-methylpropanoyl]-methylamino]-4-(2-methylphenyl)pyridin-2-yl]-1-methylpiperazin-1-ium-1-yl]methyl hydrogen phosphate (4-{5-[{2-[3,5-Bis(trifluoromethyl)phenyl]-2-methylpropanoyl}(methyl)amino]-4-(2-methylphenyl)-2-pyridinyl}-1-methylpiperazin-1-ium-1-yl)methyl hydrogen phosphate 07-PNET 10146 CAS 1703748-89-3 HCL 1643757-72-5 FDA 2014 AND EMA 2015 Фоснетупитант [Russian] [INN] فوسنيتوبيتانت [Arabic] [INN] 磷奈匹坦 [Chinese] [INN] 07-PNET In April 2018, the U.S. Food and Drug Administration (FDA) and the Swiss company Helsinn approved the intravenous formulation of AKYNZEO® (NEPA, a fixed antiemetic combination …
Centhaquine
It’s only fair to share… Centhaquine PMZ-2010 CAS 57961-90-7 2-[2-[4-(3-methylphenyl)piperazin-1-yl]ethyl]quinoline INDIA 2020, 14.05.2020, Centhaquine citrate bulk and Centhaquine citrate injection 1.0mg/vial, Add on resuscitative agent for hypovolemic shock OriginatorMidwestern University; Pharmazz DeveloperPharmazz ClassAnalgesics; Antihaemorrhagics; Antihypertensives; Cardiovascular therapies; Piperazines; Quinolines; Small molecules Mechanism of ActionAlpha 1 adrenergic receptor antagonists; Alpha 2 adrenergic receptor agonists RegisteredHaemorrhagic shock Phase IHeart …