It’s only fair to share… Edotreotide gallium Ga-68 エドトレオチドガリウム (68Ga); Edotreotide Gallium Ga-68 Gallium (68Ga) edotreotide Gallium edotreotide Ga-68 Gallium Ga 68-dotatoc Gallium Ga 68-edotreotide Gallium Ga-68 edotreotide gallium;2-[4-[2-[[(2R)-1-[[(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-4-[[(1S,2R)-1-carboxy-2-hydroxypropyl]carbamoyl]-7-[(1R)-1-hydroxyethyl]-16-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicos-19-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-2-oxoethyl]-7,10-bis(carboxylatomethyl)-1,4,7,10-tetrazacyclododec-1-yl]acetate L-threonine, N-[[(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-7-[(1R)-1-hydroxyethyl]-16-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-19-[[(2R)-1-oxo-3-phenyl-2-[[2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]amino]propyl]amino]-1,2-dithia-5,8,11,14,17-pentaazacycloeicos-4-yl]carbonyl]-, gallium salt (1:1) 2,2′,2”-[10-(2-{[(2R)-1-{[(4R,7S,10S,13R,16S,19R)-10-(4-Aminobutyl)-4-{[(1S,2R)-1-carboxy-2-hydroxypropyl]carbamoyl}-16-(4-hydroxybenzyl)-7-[(1R)-1-hydroxyéthyl]-13-(1H-indol-3-ylméthyl)-6,9,12,15,18 -pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-19-yl]amino}-1-oxo-3-phényl-2-propanyl]amino}-2-oxoéthyl)-1,4,7,10-tétraazacyclododécane-1,4,7-triyl]triacétate de gallium Gallium 2,2′,2”-[10-(2-{[(2R)-1-{[(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-4-{[(1S,2R)-1-carboxy-2-hydroxypropyl]carbamoyl}-16-(4-hydroxybenzyl)-7-[(1R)-1-hydroxyethyl]-13-(1H-indol-3-ylmethyl)-6,9, 12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-19-yl]amino}-1-oxo-3-phenyl-2-propanyl]amino}-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl]triacetate gallium 2,2′,2”-[10-(2-{[(2R)-1-{[(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-4-{[(1S,2R)-1-carboxy-2-hydroxypropyl]carbamoyl}-16-(4-hydroxybenzyl)-7-[(1R)-1-hydroxyethyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-19-yl]amino}-1-oxo-3-phenylpropan-2-yl]amino}-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl]triacetate L-Threonine, N-[[(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-7-[(1R)-1-hydroxyethyl]-16-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-19-[[(2R)-1-oxo-3-phenyl-2-[[2-[4,7,10-tr is(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]amino]propyl]amino]-1,2-dithia-5,8,11,14,17-pentaazacycloeicos-4-yl]carbonyl]-, gallium salt (1:1) L-threonine, N-[[(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-7-[(1R)-1-hydroxyethyl]-16-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-19-[[(2R)-1-oxo-3-phenyl-2-[[2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]amino]propyl]amino]-1,2-dithia-5,8,11,14,17-pentaazacycloeicos-4-yl]carbonyl]-, gallium salt …
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Nilotinib ニロチニブ;
It’s only fair to share… NILOTINIB ニロチニブ; Molecular FormulaC28H22F3N7O Average mass529.516 Da 4-Methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide 4-Methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)benzamide 4-Methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide 4-Methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluormethyl)phenyl]-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}benzolcarboxamid 4-Methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-{[4-(3-pyridinyl)-2-pyrimidinyl]amino}benzamide 4-Methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}benzamide 641571-10-0 [RN] 8654 Benzamide, 4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]- Nilotinib (AMN107, trade name Tasigna[2]), in the form of the hydrochloride monohydrate salt, is a small-molecule tyrosine kinase inhibitor approved for the treatment of imatinib-resistant chronic myelogenous leukemia.[3] Structurally related to imatinib,[4] it was developed based on the structure of the Abl-imatinib complex to …
LENALIDOMIDE, レナリドミド, леналидомид , ليناليدوميد , 来那度胺 ,
It’s only fair to share… LENALIDOMIDE Molecular FormulaC13H13N3O3 Average mass259.261 Da レナリドミド; леналидомид , ليناليدوميد , 来那度胺 , 191732-72-6 [RN] 1-Oxo-4-amino-2-(2,6-dioxopiperidin-3-yl)isoindole 2,6-Piperidinedione, 3-(4-amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)- 3-(4-amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione 3-(4-Amino-1-oxo-1,3-dihydro-2H-isoindol-2-yl)-2,6-piperidinedione 3-(4-Amino-1-oxo-1,3-dihydro-2H-isoindol-2-yl)piperidin-2,6-dion 3-(4-amino-1-oxo-1,3-dihydro-2H-isoindol-2-yl)piperidine-2,6-dione 3-(4-amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione 3-(7-amino-3-oxo-1h-isoindol-2-yl)piperidine-2,6-dione 8505 E3 Ligase ligand IMiD3 CAS Registry Number: 191732-72-6 CAS Name: 3-(4-Amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione Additional Names: 1-oxo-2-(2,6-dioxopiperidin-3-yl)-4-aminoisoindoline Manufacturers’ Codes: CC-5013 Trademarks: Revimid (Celgene); Revlimid (Celgene) Molecular Formula: C13H13N3O3 Molecular Weight: 259.26 Percent Composition: C 60.22%, H 5.05%, N 16.21%, O 18.51% Literature …
Benvitimod, Tapinarof, тапинароф , تابيناروف , 他匹那罗 ,
It’s only fair to share… Benvitimod, Tapinarof 3,5-dihydroxy-4-isopropyl-trans-stilbene Launched – 2019 CHINA, Psoriasis, Tianji Pharma тапинароф [Russian] [INN]WBI-1001 تابيناروف [Arabic] [INN] 他匹那罗 [Chinese] [INN] (E)-2-(1-Methylethyl)-5-(2-phenylethenyl)-1,3-benzenediol 1,3-Benzenediol, 2-(1-methylethyl)-5-(2-phenylethenyl)-, (E)- 1,3-Benzenediol, 2-(1-methylethyl)-5-[(E)-2-phenylethenyl]- 10253 2-Isopropyl-5-[(E)-2-phenylvinyl]-1,3-benzenediol 3,5-Dihydroxy-4-isopropyl-trans-stilbene 5-[(E)-2-phenylethenyl]-2-(propan-2-yl)benzene-1,3-diol 79338-84-4 [RN] 84HW7D0V04 Research Code：WB-1001; WBI-1001 Trade Name：MOA：NSAID Indication：Atopic dermatitis; PsoriasisStatus： Phase III (Active) Company：GlaxoSmithKline (Originator), Welichem Biotech (Originator), 天济药业 (Originator) 2894512 DMVT-505 GSK-2894512 RVT-505 WB-1001 WBI-1001 84HW7D0V04 (UNII code) In May 2019, the drug …
CANERTINIB
It’s only fair to share… CANERTINIB Canertinib CAS Registry Number: 267243-28-7 CAS Name: N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]-6-quinazolinyl]-2-propenamide Additional Names: N-[4-(3-chloro-4-fluorophenylamino)-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]acrylamide Molecular Formula: C24H25ClFN5O3 Molecular Weight: 485.94 Percent Composition: C 59.32%, H 5.19%, Cl 7.30%, F 3.91%, N 14.41%, O 9.88% Literature References: Irreversible pan-erbB tyrosine kinase inhibitor. Prepn: A. J. Bridges et al., WO 0031048; eidem, US 6344455 (2000, 2002 both to Warner-Lambert); J. B. Smaill et al., J. Med. Chem. 43, 1380 (2000). …
Cilastatin, циластатин , سيلاستاتين , 西司他丁 ,
It’s only fair to share… Cilastatin シラスタチン циластатин [Russian] [INN] سيلاستاتين [Arabic] [INN] 西司他丁 [Chinese] [INN] UNII141A6AMN38 CAS number 82009-34-5 WeightAverage: 358.453 Monoisotopic: 358.156242642 Chemical FormulaC16H26N2O5S (L)-7-(2-Amino-2-carboxy-ethylsulfanyl)-2-[(2,2-dimethyl-cyclopropanecarbonyl)-amino]-hept-2-enoic acid (Z)-(S)-6-carboxy-6-[(S)-2,2-dimethylcyclopropanecarboxamido]hex-5-enyl-L-cysteine (Z)-7-((R)-2-Amino-2-carboxy-ethylsulfanyl)-2-[((S)-2,2-dimethyl-cyclopropanecarbonyl)-amino]-hept-2-enoic acid (2Z)-7-{[(2R)-2-amino-2-carboxyethyl]sulfanyl}-2-{[(1S)-2,2-dimethylcyclopropyl]formamido}hept-2-enoic acid MK 0791|Primaxin® Primaxin® TL8005438 UNII:141A6AMN38 UNII-141A6AMN38 EINECS 279-875-8 Cilastatin CAS Registry Number: 82009-34-5 CAS Name: (2Z)-7-[[(2R)-2-Amino-2-carboxyethyl]thio]-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-2-heptenoic acid Manufacturers’ Codes: MK-791 Molecular Formula: C16H26N2O5S Molecular Weight: 358.45 Percent Composition: C 53.61%, H 7.31%, N 7.82%, …
J-147
It’s only fair to share… J-147 N-(2,4-Dimethylphenyl)-2,2,2-trifluoro-N’-[(E)-(3-methoxyphenyl)methylene]acetohydrazide Molecular FormulaC18H17F3N2O2 Average mass350.335 Da 2,2,2-trifluoroacetic acid-1-(2,4-dimethylphenyl)-2-[(3-methoxyphenyl)methylene]hydrazide Acetic acid, 2,2,2-trifluoro-, 1-(2,4-dimethylphenyl)-2-[(1E)-(3-methoxyphenyl)methylene]hydrazide N-(2,4-Dimethylphenyl)-2,2,2-trifluoro-N’-[(E)-(3-methoxyphenyl)methylene]acetohydrazide [1146963-51-0] 1-(2,4-dimethylphenyl)-2-[(3-methoxyphenyl)methylene]hydrazide, 2,2,2-trifluoro-acetic acid 1146963-51-0 [RN] DOUBLE BOND GEOMETRY UNSPECIFIED 1807913-16-1 [RN] AS PER https://chem.nlm.nih.gov/chemidplus/sid/1807913161 E FORM FDA UNII Z41H3C5BT9 Abrexa Pharmaceuticals, Dementia, Alzheimer’s type, PHASE1 Blanchette Rockefeller Neurosci Inst (Originator) Salk Institute for Biological Studies (Originator) Abrexa Pharmaceuticals is …
Dicycloplatin
It’s only fair to share… Dicycloplatin Platinum(2+) 1-carboxycyclobutanecarboxylate ammoniate (1:2:2) Molecular FormulaC12H20N2O8Pt Average mass515.380 Da 287402-09-9 Has antineoplastic activity; a supramolecular complex of 1,1-cyclobutane dicarboxylic acid and cis-diammine(1,1-cyclobutane dicarboxylate)platinum (II). 1,1-Cyclobutanedicarboxylic acid, ammonium platinum(2+) salt (2:2:1) [ACD/Index Name] Platinum(2+) 1-carboxycyclobutanecarboxylate ammoniate (1:2:2) 287402-09-9 [RN] DICYCLOPLATIN UNII:0KC57I4UNB Dicycloplatin is a chemotherapy medication used to treat a number of cancers …
Octamoxin, октамоксин , أوكتاموكسين , 奥他莫辛 ,
It’s only fair to share… Octamoxin Molecular FormulaC8H20N2 Average mass144.258 Da Octan-2-ylhydrazine Octomoxine UNII:0HXY3M6S54 UNII:2NJ66SLA5C UNII:895PL98ZMY 4684-87-1 [RN] 65500-65-4 [RN] 895PL98ZMY 0HXY3M6S54 1776 2-Hydrazinooctane 2NJ66SLA5C CAS Registry Number: 4684-87-1 CAS Name: (1-Methylheptyl)hydrazine Additional Names: 2-hydrazinooctane; octomoxine Trademarks: Ximaol Molecular Formula: C8H20N2 Molecular Weight: 144.26 Percent Composition: C 66.61%, H 13.97%, N 19.42% Literature References: Monoamine oxidase inhibitor. Prepd by condensation of methyl hexyl ketone and …
CK-101
It’s only fair to share… CK-101, RX-518 CAS 1660963-42-7 MF C29 H28 F2 N6 O2 MW 530.57 2-Propenamide, N-[3-[2-[[2,3-difluoro-4-[4-(2-hydroxyethyl)-1-piperazinyl]phenyl]amino]-8-quinazolinyl]phenyl]- N-[3-[2-[[2,3-Difluoro-4-[4-(2-hydroxyethyl)piperazin-1-yl]phenyl]amino]quinazolin-8-yl]phenyl]acrylamide N-(3-(2-((2,3-Difluoro-4-(4-(2-hydroxyethyl)piperazin-1-yl)phenyl)amino)quinazolin-8-yl)phenyl)acrylamide EGFR-IN-3 UNII-708TLB8J3Y 708TLB8J3Y AK543910 Suzhou NeuPharma (Originator) Checkpoint Therapeutics Non-Small Cell Lung Cancer Therapy Solid Tumors Therapy PHASE 2 Checkpoint Therapeutics, Cancer, lung (non-small cell) (NSCLC), solid tumour RX518(CK-101) is an orally available third-generation and selective inhibitor of certain epidermal growth factor …