It’s only fair to share… Safinamide Molecular Formula C17H19FN2O2 Average mass 302.343 Da (2S)-2-[[[4-[(3-Fluorophenyl)methoxy]phenyl]methyl]amino]propanamide 133865-89-1 , сафинамид , سافيناميد , 沙非胺 , EMD-1195686, ZP-034, FCE-28073(R-isomer), PNU-151774E, NW-1015, FCE-26743 CAS 202825-46-5 (mesylate) SEE BELOW (+)-(S)-2-[[p-[(m-fluorobenzyl)oxy]benzyl]amino]propionamide monomethanesulfonate Propanamide, 2-[[[4-[(3-fluorophenyl)methoxy]phenyl]methyl]amino]-, (2S)-, methanesulfonate Molecular Weight 398.45 Formula C17H19FN2O2 ● CH4O3S CAS 202825-46-5 (Safinamide Mesylate) Safinamide is a white to off-white, non-hygroscopic crystalline solid. It shows pH dependent …
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New paper on Trelagliptin succinate
It’s only fair to share… Trelagliptin succinate, a novel once-weekly oral dipeptidyl peptidase-4 (DPP-4) inhibitor, was approved for the Japanese market on March 26, 2015 Trelagliptin exhibited a better potency against human DPP-4 than alogliptin and sitagliptin, along with its excellent selectivity and slow-binding properties that may partially contribute to its sustained efficacy. In phase III …
Regioselective access of alkylidendibenzo[c,f]oxocine framework via cyclocarbopalladation/cross-coupling cascade reactions and reductive Heck strategy
It’s only fair to share… Regioselective access of alkylidendibenzo[c,f]oxocine framework via cyclocarbopalladation/cross-coupling cascade reactions and reductive Heck strategy New J. Chem., 2017, Advance Article DOI: 10.1039/C6NJ03825E, Paper Tapas Ghosha a Institute of Organic Chemistry, University of Würzburg, Am Hubland, 97074 Würzburg, Germany E-mail: tapas.ghosh@uni-wuerzburg.de,tapasghosh.chem@gmail.com Tel: +49-931-31-81629 New J. Chem., 2017, Advance Article DOI: 10.1039/C6NJ03825E Palladium-catalyzed …
How to Apply for an International Patent
It’s only fair to share… How to Apply for an International Patent Part1 Determining the Patentability of your Invention 1Determine if you have a patentable invention. U.S. law sets forth the following requirements for something that can be patented: It must be invented or discovered by a person; It must be a new and useful …
Asymmetric total synthesis of (-)-δ-lycorane
It’s only fair to share… 1H NMR 13C NMR Org. Chem. Front., 2017, Advance Article DOI: 10.1039/C7QO00021A, Research Article Junliang Wang, Jianneng Li, Xianwang Shen, Cong Dong, Jun Lin, Kun Wei A first asymmetric synthesis of (-)-δ-lycorane by using a chiral bifunctional squaramide-catalysed cascade reaction is reported. Asymmetric total synthesis of (−)-δ-lycorane Junliang Wang,ab Jianneng …
4-Pentenoic acid, 5-(3,4-methylenedioxyphenyl)-3-oxo-, ethyl ester
It’s only fair to share… 4-Pentenoic acid, 5-(3,4-methylenedioxyphenyl)-3-oxo-, ethyl ester cas 860547-52-0 MF C14 H14 O5 4-Pentenoic acid, 5-(1,3-benzodioxol-5-yl)-3-oxo-, ethyl ester Molecular Weight, 262.26 Melting Point (Experimental) Value: 58-60 °C Purification of the residue by flash column chromatography (10% ethyl acetate in hexanes) afforded the β-keto ester (12.0 g, 90%) as a pale yellow oil. …
DRAFTING A NON-PROVISIONAL PATENT APPLICATION
It’s only fair to share… DRAFTING A NON-PROVISIONAL PATENT APPLICATION! Part1 Determining the Patentability of your Invention 1Determine if you have a patentable invention. U.S. law sets forth the following requirements for something that can be patented: It must be invented or discovered by a person; It must be a new and useful process, machine, …
How do I get a patent in India ?
It’s only fair to share… How much does getting a patent in India costs? There is no precise and accurate answer to this question as cost for a obtaining patent is dependent on mutiple factors… What best we can have is range for costs involved in… There are two elements for cost of getting patent …
Dimethylcarbamoyl Chloride, a known carcinogen
It’s only fair to share… Identifiers CAS Number 79-44-7 ECHA InfoCard 100.001.099 PubChem 6598 Properties Chemical formula C3H6ClNO Dimethylcarbamoyl Chloride Mechanisms for the Formation of Dimethylcarbamoyl Chloride Thionyl chloride is the most common reagent in process chemistry for the conversion of a carboxylic acid to an acid chloride. One of the primary factors is cost, since …
GDC 0994, Ravoxertinib
It’s only fair to share… GDC 0994 GDC-0994; Ravoxertinib; 1453848-26-4; GDC0994; UNII-R6AXV96CRH; R6AXV96CRH, RG7842; RG-7842; RG 7842 CAS 1453848-26-4 1-[(1S)-1-(4-chloro-3-fluorophenyl)-2-hydroxyethyl]-4-[2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]pyridin-2-one Molecular Formula: C21H18ClFN6O2 Molecular Weight: 440.863 g/mol PHASE 1 Ravoxertinib also known as GDC-0994 and RG7842, is an orally available inhibitor of extracellular signal-regulated kinase (ERK), with potential antineoplastic activity. Upon oral administration, GDC-0994 inhibits …