It’s only fair to share… Afloqualone Molecular Formula: C16H14FN3O Molecular Weight: 283.306 g/mol 6-amino-2-(fluoromethyl)-3-(2-methylphenyl)quinazolin-4-one HQ 495, C033541, QA-3735, UNII:CO4U2C8ORZ 4(3H)-Quinazolinone, 6-amino-2-(fluoromethyl)-3-(2-methylphenyl)- [ACD/Index Name] 4831 56287-74-2 [RN], アフロクアロン Afloqualone; 56287-74-2; Arofuto; Aroft; Afloqualon; Afloqualone [INN:JAN] Afloqualone (Arofuto) is a quinazolinone family GABAergic drug and is an analogue of methaqualone developed in the 1970s by a team at Tanabe Seiyaku.[1] It has sedative and muscle-relaxant effects resulting from its agonist activity at the β subtype of …
Doxepin, ドキセピン
It’s only fair to share… Doxepin 1668-19-5 1229-29-4 (hydrochloride), 4698-39-9 ((E)-isomer); 25127-31-5 ((Z)-isomer) Launched – 1964 1-Propanamine, 3-dibenz(b,e)oxepin-11(6H)-ylidene-N,N-dimethyl- 1-Propanamine, 3-dibenz[b,e]oxepin-11(6H)-ylidene-N,N-dimethyl-, (3Z)- 3-(Dibenzo[b,e]oxepin-11(6H)-ylidene)-N,N-dimethylpropan-1-amine N,N-Dimethyldibenz[b,e]oxepin-D11(6H),g-propylamine (3Z)-3-(Dibenzo[b,e]oxepin-11(6H)-ylidene)-N,N-dimethylpropan-1-amine Doxepin Hydrochloride 3U9A0FE9N5 1229-29-4 NSC-108160 P-3693A SO-101 Aponal Quitaxon Silenor Sinequan Sinquan Xepin Zonalon USP USP32/pub/data/v32270/usp32nf27s0_m28110 N,N-Dimethyldibenz[b,e]oxepin-D11(6H),-propylamine hydrochloride [1229-29-4; 4698-39-9 ((E)-isomer); 25127-31-5 ((Z)-isomer)]. » Doxepin Hydrochloride, an (E) and (Z) geometric isomer mixture, contains the equivalent of not less …
Penciclovir
It’s only fair to share… Penciclovir Molecular FormulaC10H15N5O3 Average mass253.258 Da Cas 39809-25-1 97845-62-0 (Na salt) Launched – 1996 PERRIGO, Herpes labialis 2-Amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)butyl]-6H-purin-6-one 2-Amino-9-[4-hydroxy-3-(hydroxymethyl)butyl]-1,9-dihydro-6H-purin-6-one 2-Amino-9-[4-hydroxy-3-(hydroxyméthyl)butyl]-1,9-dihydro-6H-purin-6-one 359HUE8FJC BRL-39123; penciclovir; BRL 39123A; penciclovir sodium; Denavir; Vectavir; Euraxvir; Fenivir Penciclovir [USAN:INN:BAN] BRL 39123 BRL-39123 CCRIS 9213 Denavir HSDB 8123 Penciclovir Penciclovirum Penciclovirum [INN-Latin] UNII-359HUE8FJC Title: Penciclovir CAS Registry …
Isavuconazonium sulfate, Изавуконазониев сулфат
It’s only fair to share… Isavuconazonium sulfate Изавуконазониев сулфат CAS 946075-13-4 MOLECULAR FORMULA: C35H36F2N8O9S2 MOLECULAR WEIGHT: 814.837 g/mol BAL-8557-002, BAL 8557 [2-[1-[1-[(2R,3R)-3-[4-(4-cyanophenyl)-1,3-thiazol-2-yl]-2-(2,5-difluorophenyl)-2-hydroxybutyl]-1,2,4-triazol-4-ium-4-yl]ethoxycarbonyl-methylamino]pyridin-3-yl]methyl 2-(methylamino)acetate;hydrogen sulfate UNII:31Q44514JV (2-{[(1-{1-[(2R,3R)-3-[4-(4-cyanophenyl)-1,3-thiazol-2-yl]-2-(2,5-difluorophenyl)-2-hydroxybutyl]-1H-1,2,4-triazol-4-ium-4-yl}ethoxy)carbonyl](methyl)amino}pyridin-3-yl)methyl N-methylglycinate hydrogen sulfate (2-{[(1-{1-[(2R,3R)-3-[4-(4-Cyanophenyl)-1,3-thiazol-2-yl]-2-(2,5-difluorophenyl)-2-hydroxybutyl]-1H-1,2,4-triazol-4-ium-4-yl}ethoxy)carbonyl](methyl)amino}-3-pyridinyl)methyl N-methylglycinate hydrog en sulfate FDA 2015, EU 2015, BAL8557-002, BCS CLASS I, RO-0098557 , AK-1820 fast track designation QIDP ORPHAN DRUG EU 1-{(2R,3R)-3-[4-(4-cyanophenyl)-1,3- thiazol-2-yl]-2-(2,5-difluoro-phenyl)-2-hydroxybutyl}-4-[(1RS)-1-({methyl[3-({[(methylamino)acetyl] oxy}methyl) pyridin-2-yl]carbamoyl}oxy)ethyl]-1H-1,2,4-triazol-4-ium monosulfate (IUPAC), …
Chenodeoxycholic acid, ケノデオキシコール酸
It’s only fair to share… Chenodeoxycholic acid Chenodiol Molecular FormulaC24H40O4 Average mass392.572 UNII-0GEI24LG0J ケノデオキシコール酸 474-25-9 [RN] chenodeoxycholic acid [JP15] [Wiki] (+)-chenodeoxycholic acid (3a,5b,7a)-3,7-dihydroxy-cholan-24-oic acid (3α,5β,7α,8ξ,20R)-3,7-Dihydroxycholan-24-säure[German] [ACD/IUPAC Name] (4R)-4-[(3R,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid 0GEI24LG0J 17b-(1-Methyl-3-carboxypropyl)etiocholane-3a,7a-diol 207-481-8[EINECS] 3a,7a-dihydroxy-5b-cholan-24-oic acid 3a,7a-dihydroxy-5b-cholanic acid; anthropodesoxycholic acid; gallodesoxycholic acid; 17b-(1-methyl-3-carboxypropyl)etiocholane-3a,7a-diol; chenic acid; chenodeoxycholic acid; CDC Chenodeoxycholate; Chenodeoxycholic acid; 3alpha,7alpha-Dihydroxy-5beta-cholanic acid; Chenodiol Synthesis ReferenceHenry Francis Frost, Fritz Fabian, Christopher James …
VORAPAXAR SULPHATE
It’s only fair to share… VORAPAXAR Thrombosis, Antiplatelet Therapy, PAR1 Antagonists , MERCK ..ORIGINATOR Ethyl N-[(3R,3aS,4S,4aR,7R,8aR,9aR)-4-[(E)-2-[5-(3-fluorophenyl)-2-pyridyl]vinyl]-3-methyl-1-oxo-3a,4,4a,5,6,7,8,8a,9,9a-decahydro-3H-benzo[f]isobenzofuran-7-yl]carbamate Carbamic acid, [(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)-2- pyridinyl]ethenyl]dodecahydro-1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]-, ethyl ester Carbamic acid, N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(E)-2-[5-(3-fluorophenyl)-2-pyridinyl]ethenyl]dodecahydro-1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]-, ethyl ester Ethyl [(1R,3aR,4aR,6R,8aR,9S,9aS)-9-{(E)-2-[5-(3-fluorophenyl)-2-pyridinyl]vinyl}-1-methyl-3-oxododecahydronaphtho[2,3-c]furan-6-yl]carbamate Ethyl ((1R,3aR,4aR,6R,8aR,9S,9aS)-9-((1E)-2-(5-(3-fluorophenyl)pyridin-2-yl)ethenyl)- 1-methyl-3-oxododecahydronaphtho(2,3-c)furan-6-yl)carbamate Carbamic acid, ((1R,3aR,4aR,6R,8aR,9S,9aS)-9-((1E)-2-(5-(3-fluorophenyl)-2- pyridinyl)ethenyl)dodecahydro-1-methyl-3-oxonaphtho(2,3-c)furan-6-yl)-, ethyl ester 618385-01-6 CAS NO FREE FORM CAS Number: 705260-08-8 SULPHATE Has antiplatelet activity. Also known as: SCH-530348, MK-5348 Molecular Formula: C29H33FN2O4 Molecular Weight: 492.581723 ZCE93644N2 …
Gadobenate Dimeglumine
It’s only fair to share… Gadobenate Dimeglumine Molecular Formula: C36H62GdN5O21 Molecular Weight: 1058.156 g/mol cas 113662-23-0 FREEFORM INGREDIENT UNII CAS Gadobenate dimeglumine 3Q6PPC19PO 127000-20-8 Used in MR imaging of liver. UNII-15G12L5X8K 3,6,9-triaza-12-oxa-3,6,9-tricarboxymethylene-10-carboxy-13-phenyltridecanoic acid, gadolinium B 19036 B-19036 gadobenate dimeglumine gadobenic acid gadobenic acid, dimeglumine salt gadolinium-benzyloxypropionyl tetraacetate gadolinium-BOPTA-Dimeg Gd(BOPTA)2 Gd-BOPTA Multihance (TN) E-7155 2-[2-[carboxylatomethyl-[2-[carboxylatomethyl(carboxymethyl)amino]ethyl]amino]ethyl-(carboxymethyl)amino]-3-phenylmethoxypropanoate;gadolinium(3+);(2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol gadolinium(3+) ion …
THELIATINIB
It’s only fair to share… THELIATINIB CAS: 1353644-70-8 Chemical Formula: C25H26N6O2 Molecular Weight: 442.523 HMPL-309; HMPL 309; HMPL309; Theliatinib. Originator Hutchison MediPharma Class Antineoplastics; Small molecules Mechanism of Action Epidermal growth factor receptor antagonists Highest Development Phases Phase I Oesophageal cancer; Solid tumours Most Recent Events 29 Sep 2017 Efficacy and adverse events data from a phase I …
Alatrofloxacin mesylate
It’s only fair to share… Alatrofloxacin Mesylate Chemical Names: Alatrofloxacin mesylate; UNII-2IXX802851; 146961-77-5; Alatrofloxacin mesylate [USAN]; 157605-25-9; 2IXX802851 Molecular Formula: C27H29F3N6O8S Molecular Weight: 654.618 g/mol CAS No. 146961-76-4 (Alatrofloxacin ); 157605-25-9 (Alatrofloxacin Mesylate); Chemical Name (1α, 5α, 6α)-L-alanyl-N-[3-[6-carboxy-8-(2,4-difluorophenyl)-3-fluoro-5,8-dihydro-5-oxo-1,8-naphthyridine-2-yl]-3-azabicyclo[3.1.0]hex-6-yl]-L-alaninamide, monomethanesulfonate Research Code：CP-116517-27; CP-116517, Trade Name：Trovan I.V.® MOA：Quinolone antibiotic Indication：Life- or …
RG 7604,Taselisib
It’s only fair to share… Molecular FormulaC24H28N8O2 Average mass460.531 Da RG7604,Taselisib GDC-0032, GDC0032;GDC 0032, RO5537381 1282512-48-4 [RN] 1H-Pyrazole-1-acetamide, 4-[5,6-dihydro-2-[3-methyl-1-(1-methylethyl)-1H-1,2,4-triazol-5-yl]imidazo[1,2-d][1,4]benzoxazepin-9-yl]-α,α-dimethyl- UNII:L08J2O299M 10.1021/jm4003632 2-(4-(2-(1-isopropyl-3-methyl-1H-1,2,4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)-1H-pyrazol-1-yl)-2-methylpropanamide 2-{3-[2-(1-Isopropyl-3-methyl-1H-1,2–4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl]-1H-pyrazol-1-yl}-2-methylpropanamide NMR http://file.selleckchem.com/downloads/nmr/s710301-gdc-0032-hnmr-selleck.pdf POLYMORPHS almost A to Z, US9266903 Taselisib (GDC-0032) is an experimental cancer drug in development by Roche. Molecule is a complex heterocycle with no chiral centres, hazardous materials are used in synthesis, …