It’s only fair to share… CAS 186348-69-6 1,4-Benzodioxin-5-carboxamide, 8-amino-7-chloro-N-(1,4-diazabicyclo[2.2.2]oct-2-ylmethyl)-2,3-dihydro-, (-)- MW, 352.82, C16 H21 Cl N4 O3 US5663173 (A) – N-[(1,4-diazabicyclo[2.2.2] oct-2-yl)methyl] benzamide derivatives, their preparations and their application in therapeutics SL65.0102-10 (-)-1,4-benzodioxin-5-carboxamide-8-amino-7-chloro-N-(1,4-diazabicyclo[2.2.2]oct-2- ylmethyl)-2,3-dihydro-, hydrochloride 1,4-Benzodioxin-5-carboxamide, 8-amino-7-chloro-N-(1,4-diazabicyclo[2.2.2]oct-2-ylmethyl)-2,3-dihydro-, hydrochloride (1:2), (-)- 1,4-Benzodioxin-5-carboxamide, 8-amino-7-chloro-N-(1,4-diazabicyclo[2.2.2]oct-2-ylmethyl)-2,3-dihydro-, dihydrochloride, (-)- Dihydrochloride (-) – 8-Amino-7-chloro- N – [(1,4-diazabicyclo [2.2.2] oct-2-yl) methyl] -2,3-dihydro-1,4-benzodioxin-5 -carboxamide. …
Production of High-Quality Diesel from Biomass Waste Products
It’s only fair to share… The use of biodiesel has been promoted for the past decade as a substitute for fossil-based diesel fuel. However, it has become evident that its production competes with food production by engrossing cropland. To overcome this Corma has developed a process that uses 2-methylfuran which currently is isolated (280 × …
Acid Chloride Negishi Couplings
It’s only fair to share… With the plethora of new and efficient C–C bond-forming reactions available to the organic chemists growing on a monthly basis, one area that suffers is the substrate scope for previously reported examples. In this case Kim and Reike ( Tetrahedron Lett. 2011, 52, 1523−1526) reinvestigate work originally reported by Rovis. …
Cimaglermin alfa , GGF2
It’s only fair to share… Cimaglermin alfa , GGF2 RN: 1350717-96-2, UNII: B2A4EZ9I83 CGF-2; GGF-2 – Acorda; Glial growth factor 2 – Acorda; Neuregulin 1 protein; Neuregulin 1β3; NRG1 protein; Recombinant human glial growth factor-2 (rhGGF 2) – Acorda Therapeutics; rhGGF2 – Acorda Treatment of Congestive Heart Failure, rhGGF 2 Molecular Formula, C1747-H2770-N502-O535-S17 (unglycosylated), Molecular Weight, 39923.2958 Glial growth …
WO 2016200930, New patent, Citarinostat, Acetylon Pharmaceuticals Inc
It’s only fair to share… WO 2016200930, New patent, Citarinostat, Acetylon Pharmaceuticals Inc citarinostat Acetylon Pharmaceuticals Inc (WO2016200930) METHODS OF MAKING PROTEIN DEACETYLASE INHIBITORS (I) Compound (I) is disclosed in U.S. Patent No. 8,148,526 as an HDAC inhibitor. Example 2 of U.S. Patent Application Publication No. 2015/0099744 discloses a synthesis of compound (I). As detailed …
Calcifediol, カルシフェジオール
It’s only fair to share… Calcifediol カルシフェジオール Ro 8-8892 U 32070E (3b,5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-3,25-diol (3S,5Z,7E,20R)-9,10-Secocholesta-5,7,10-trien-3,25-diol [German] [ACD/IUPAC Name] (3S,5Z,7E,20R)-9,10-Secocholesta-5,7,10-triene-3,25-diol [ACD/IUPAC Name] (3S,5Z,7E,20R)-9,10-Sécocholesta-5,7,10-triène-3,25-diol [French] [ACD/IUPAC Name] 19356-17-3 [RN] 1H-indene-1-pentanol, octahydro-4-[(2Z)-2-[(5S)-5-hydroxy-2-methylenecyclohexylidene]ethylidene]-a,a,e,7a-tetramethyl-, (eR,1R,3aS,4E,7aR)- 25(OH)D3 25-(OH)Vitamin D3 25-hydroxy Vitamin D3 25-HYDROXYCHOLECALCIFEROL-D6 25-hydroxycholecalciferolmonohydrate 25-hydroxyvitamin D 3-{2-[1-(5-Hydroxy-1,5-dimethyl-hexyl)-7a-methyl-octahydro-inden-4-ylidene]-ethylidene}-4-methylene-cyclohexanol 4-[(2Z)-2-[(5S)-5-hydroxy-2-methylenecyclohexylidene]ethylidene]octahydro-?,?,?,7a-tetramethyl-(?R,1R,3aS,4E,7aR)-1H-indene-1-pentanol Molecular form.: C₂₇H₄₄O₂ Appearance: White to Off-White Solid Melting Point: 75-93ºC Mol. Weight: 400.64 Calcifediol …
Balsalazide
It’s only fair to share… Balsalazide 80573-04-2; Colazal; Balsalazide Disodium; AC1NSFNR; P80AL8J7ZP; Molecular Formula: C17H15N3O6 Molecular Weight: 357.322 g/mol (3E)-3-[[4-(2-carboxyethylcarbamoyl)phenyl]hydrazinylidene]-6-oxocyclohexa-1,4-diene-1-carboxylic acid DISODIUMDIHYDRATE CAS Number 150399-21-6 Weight Average: 437.316 Monoisotopic: 437.08110308 Chemical Formula C17H17N3Na2O8 Balsalazide is an anti-inflammatory drug used in the treatment of inflammatory bowel disease. It is sold under the brand names Giazo, …
CENTANAFADINE
It’s only fair to share… Centanafadine; UNII-D2A6T4UH9C; EB-1020 free base; D2A6T4UH9C; 924012-43-1 CTN SR; EB-1020; EB-1020 SR WO 2007016155 Molecular Formula: C15H15N Molecular Weight: 209.292 g/mol Phase II Attention-deficit hyperactivity disorder No development reported Major depressive disorder; Neuropathic pain Most Recent Events 20 Dec 2016 Neurovance plans a phase III trial for Attention-deficit hyperactivity disorder 27 Jul 2016 Efficacy data from …
FDA approves first drug Spinraza (nusinersen), for spinal muscular atrophy
It’s only fair to share… FDA approves first drug for spinal muscular atrophy New therapy addresses unmet medical need for rare disease The U.S. Food and Drug Administration today approved Spinraza (nusinersen), the first drug approved to treat children and adults with spinal muscular atrophy (SMA), a rare and often fatal genetic disease affecting muscle …
Niraparib; MK 4827
It’s only fair to share… MK-4827,(S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxaMide Niraparib; MK 4827; MK4827 UNII:HMC2H89N35 Antineoplastic, Poly(ADP-ribose) Polymerase Inhibitors 1038915-60-4 CAS, free form 1038915-64-8 CAS HYDROCHLORIDE 1613220-15-7 cas TOSYLATE MONOHYDRATE 1038915-73-9 TOSYLATE MK-4827(Niraparib) tosylate is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM; with great activity in cancer cells with mutant BRCA-1 and BRCA-2; >330-fold selective against …