It’s only fair to share… Voretigene neparvovec Voretigene neparvovec-rzyl; Luxturna (TN) ボレチジーンネパルボベック; DNA (synthetic adeno-associated virus 2 vector AAV2-hRPE65v2) CAS: 1646819-03-5 2017/12/19, FDA Luxturna, SPARK THERAPEUTICS Vision loss treatment, Retinal dystrophy AAV2-hRPE65v2 AAV2.RPE65 LTW-888 SPK-RPE65 rAAV.hRPE65v2 rAAV2-CBSB-hRPE65 2SPI046IKD (UNII code) melting point (°C) 72-90ºC Rayaprolu V. et al. J. Virol. vol. 87. no. 24. (2013) FDA …
TIABENDAZOLE, тиабендазол , تياباندازول , 噻苯达唑 , チアベンダゾール;
It’s only fair to share… TIABENDAZOLE CAS: 148-79-8 Molecular FormulaC10H7N3S Average mass201.248 Da тиабендазол [Russian] [INN] تياباندازول [Arabic] [INN] 噻苯达唑 [Chinese] [INN] チアベンダゾール; 1436 148-79-8 [RN] 1H-Benzimidazole, 2-(4-thiazolyl)- 2-(1,3-Thiazol-4-yl)-1H-benzimidazole 2-(4-Thiazoly)benzimidazole 205-725-8 [EINECS] 28558-32-9 [RN] 90507-06-5 [RN] Arbotect [Trade name] Benzimidazole, 2-(4-thiazolyl)- Mintezol [Trade name] N1Q45E87DT MK 360 / MK-360 / NSC-525040 / NSC-90507 Tiabendazole (INN, BAN), thiabendazole (AAN, USAN), TBZ (and the trade names Mintezol, Tresaderm, and Arbotect) is a preservative[1] 2-Substituted benzimidazole first introduced in 1962. It is active …
Elapegademase, エラペグアデマーゼ (遺伝子組換え)
It’s only fair to share… AQTPAFNKPK VELHVHLDGA IKPETILYYG RKRGIALPAD TPEELQNIIG MDKPLSLPEF LAKFDYYMPA IAGSREAVKR IAYEFVEMKA KDGVVYVEVR YSPHLLANSK VEPIPWNQAE GDLTPDEVVS LVNQGLQEGE RDFGVKVRSI LCCMRHQPSW SSEVVELCKK YREQTVVAID LAGDETIEGS SLFPGHVKAY AEAVKSGVHR TVHAGEVGSA NVVKEAVDTL KTERLGHGYH TLEDTTLYNR LRQENMHFEV CPWSSYLTGA WKPDTEHPVV RFKNDQVNYS LNTDDPLIFK STLDTDYQMT KNEMGFTEEE FKRLNINAAK SSFLPEDEKK ELLDLLYKAY GMPSPA >>Elapegademase<<< AQTPAFNKPKVELHVHLDGAIKPETILYYGRKRGIALPADTPEELQNIIGMDKPLSLPEF LAKFDYYMPAIAGSREAVKRIAYEFVEMKAKDGVVYVEVRYSPHLLANSKVEPIPWNQAE GDLTPDEVVSLVNQGLQEGERDFGVKVRSILCCMRHQPSWSSEVVELCKKYREQTVVAID LAGDETIEGSSLFPGHVKAYAEAVKSGVHRTVHAGEVGSANVVKEAVDTLKTERLGHGYH TLEDTTLYNRLRQENMHFEVCPWSSYLTGAWKPDTEHPVVRFKNDQVNYSLNTDDPLIFK STLDTDYQMTKNEMGFTEEEFKRLNINAAKSSFLPEDEKKELLDLLYKAYGMPSPA Elapegademase, エラペグアデマーゼ (遺伝子組換え) EZN-2279 Protein chemical formula C1797H2795N477O544S12 …
Fezolinetant, фезолинетант , فيزولينيتانت , 非唑奈坦 ,
It’s only fair to share… Fezolinetant ESN-364 Molecular FormulaC16H15FN6OS Average mass358.393 Da Methanone, [(8R)-5,6-dihydro-8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl](4-fluorophenyl)- UNII:83VNE45KXX фезолинетант [Russian] [INN] فيزولينيتانت [Arabic] [INN] 非唑奈坦 [Chinese] [INN] (4-Fluorophenyl)[(8R)-8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]methanone 10205 1629229-37-3 [RN] 83VNE45KXX Originator Euroscreen Developer Ogeda Class Pyrazines; Small molecules; Triazoles Mechanism of Action Gonadal steroid hormone modulators; Neurokinin 3 receptor antagonists Phase II Hot flashes; Polycystic ovary syndrome; Uterine leiomyoma Preclinical Weight gain DiscontinuedBenign prostatic hyperplasia; Endometriosis 14 Sep 2018 Ogeda completes …
Calaspargase pegol, カラスパルガーゼペゴル
It’s only fair to share… LPNITILATG GTIAGGGDSA TKSNYTAGKV GVENLVNAVP QLKDIANVKG EQVVNIGSQD MNDDVWLTLA KKINTDCDKT DGFVITHGTD TMEETAYFLD LTVKCDKPVV MVGAMRPSTS MSADGPFNLY NAVVTAADKA SANRGVLVVM NDTVLDGRDV TKTNTTDVAT FKSVNYGPLG YIHNGKIDYQ RTPARKHTSD TPFDVSKLNE LPKVGIVYNY ANASDLPAKA LVDAGYDGIV SAGVGNGNLY KTVFDTLATA AKNGTAVVRS SRVPTGATTQ DAEVDDAKYG FVASGTLNPQ KARVLLQLAL TQTKDPQQIQ QIFNQY (tetramer; disulfide bridge 77-105, 77′-105′, 77”-105”, 77”’-105”’) Calaspargase pegol Molecular Formula, C1516-H2423-N415-O492-S8 (peptide monomer), Molecular Weight, 10261.2163 …
IMETELSTAT
It’s only fair to share… IMETELSTAT CAS 868169-64-6, N163L Molecular Formula, C148-H211-N68-O53-P13-S13, Molecular Weight, 4610.2379, Nucleic Acid Sequence Sequence Length: 135 a 1 c 4 g 3 tmodified DNA d(3′-amino-3′-deoxy-P-thio)(T-A-G-G-G-T-T-A-G-A-C-A-A) 5′-[O-[2-hydroxy-3-[(1-oxohexadecyl)amino]propyl] hydrogen phosphorothioate] PHASE 3, GERON, Myelodysplasia IMETELSTAT SODIUM CAS 1007380-31-5, GRN163L, GRN 163L Sodium Salt Molecular Formula: C148H198N68Na13O53P13S13 Molecular Weight: 4895.941 g/mol 5′-(O-(2-hydroxy-3-((1-oxohexadecyl)amino)propyl)phosphorothioate)-d(3′-amino-3′-deoxy-p-thio)(t-a-g-g-g-t-t-a-g-a-c-a-a), sodium salt (13) …
Romosozumab, ロモソズマブ (遺伝子組換え)
It’s only fair to share… Romosozumab ロモソズマブ (遺伝子組換え) AMG 785 Immunoglobulin G2, anti-(human sclerostin) (human-mouse monoclonal 785A070802 heavy chain), disulfide with human-mouse monoclonal 785A070802 κ-chain, dimer Immunoglobulin G2, anti-(human sclerostin) (humanized monoclonal 785A070802 heavy chain), disulfide with humanized monoclonal 785A070802 κ-chain, dimer Formula C6452H9926N1714O2040S54 CAS 909395-70-6 Mol weight 145875.6186 Monoclonal antibody Treatment of osteoporosis Osteoporosis …
Gemigliptin tartrate sesquihydrate, ゲミグリプチン
It’s only fair to share… Gemigliptin tartrate sesquihydrate; ゲミグリプチン Molecular Weight 666.47 Formula C18H19F8N5O2 • C4H6O6 • 1.5H2O 911637-19-9 (Gemigliptin); 1375415-82-9 (Gemigliptin L-tartrate Sesquihydrate) (3S)-3-amino-4-(5,5-difluoro-2-oxopiperidino)-1-[2,4-di(trifluoromethyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-7-yl]butan-1-one L-tartrate, sesquihydrate 1-{(2S)-2-Amino-4-[2,4-bis(trifluoromethyl)-5,8-dihydropyrido[3,4-d]pyrimidin-7(6H)-yl]-4-oxobutyl}-5,5-difluoro-2-piperidinone[ACD/IUPAC Name] 2-Piperidinone, 1-[(2S)-2-amino-4-[5,8-dihydro-2,4-bis(trifluoromethyl)pyrido[3,4-d]pyrimidin-7(6H)-yl]-4-oxobutyl]-5,5-difluoro- 5DHU18M5D6 911637-19-9 [RN] FREE FORM 9291 Gemigliptin gemigliptin tartarate gemigliptin(lc15-0444) LC15-0444 MFCD19443742 UNII:5DHU18M5D6 Gemiglo®; LC-150444; Zemiglo Gemigliptin L-tartrate sesquihydrate was approved by Korean food and Drug …
Nalmefene hydrochloride dihydrate, ナルメフェン塩酸塩水和物 ,
It’s only fair to share… Nalmefene hydrochloride dihydrate, ナルメフェン塩酸塩水和物 2019/1/8, PMDA, JAPAN, Selincro, In January 2019, Otsuka received regulatory approval in Japan Antialcohol dependence, Narcotic antagonist, Opioid receptor partial agonist/antagonist Morphinan-3,14-diol, 17-(cyclopropylmethyl)-4,5-epoxy-6-methylene-, hydrochloride, hydrate (1:1:2), (5α)- Formula C21H25NO3. HCl. 2H2O CAS 1228646-70-5 5096-26-9 free form 58895-64-0 (Nalmefene HCl) Mol weight 411.9196 JF-1; NIH-10365; ORF-11676; SRD-174, Lu-AA36143 APPROVED 1995 USA Trade …
Esaxerenone エサキセレノン , эсаксеренон , إيساكسيرينون , 艾沙利 酮 ,
It’s only fair to share… Esaxerenone エサキセレノン , эсаксеренон , إيساكسيرينون , 艾沙利 酮 , CS-3150, XL-550 Formula C22H21F3N2O4S CAS 1632006-28-0 Mol weight 466.4734 Pmda approved japan, 2019/1/8, Minebro Antihypertensive, Aldosterone antagonist N62TGJ04A1 UNII:N62TGJ04A1 эсаксеренон [Russian] [INN] إيساكسيرينون [Arabic] [INN] 艾沙利酮 [Chinese] [INN] 1-(2-Hydroxyethyl)-4-methyl-N-[4-(methylsulfonyl)phenyl]-5-[2-(trifluoromethyl)phenyl]-1H-pyrrole-3-carboxamide 10230 1632006-28-0 [RN], 880780-76-7, 1072195-82-4 (+ isomer) 1072195-83-5 (- isomer) 1H-Pyrrole-3-carboxamide, 1-(2-hydroxyethyl)-4-methyl-N-[4-(methylsulfonyl)phenyl]-5-[2-(trifluoromethyl)phenyl]- Originator X-Ceptor Therapeutics Developer Daiichi Sankyo Company Class Antihyperglycaemics; Antihypertensives; Pyrroles; Small molecules; Sulfones Mechanism of Action Mineralocorticoid receptor antagonists …