It’s only fair to share… Gadopiclenol ガドピクレノール; Formula C35H54N7O15. Gd CAS 933983-75-6 Mol weight 970.0912 FDA APPROVED 2022/9/21, Elucirem Diagnostic agent (MR imaging), WHO 10744, P 03277, UNII: S276568KOY EluciremTM; G03277; P03277; VUEWAY (alpha3,alpha6,alpha9-Tris(3-((2,3-dihydroxypropyl)amino)-3-oxopropyl)-3,6,9,15-tetraazabicyclo(9.3.1)pentadeca-1(15),11,13-triene-3,6,9-triacetato(3-)-kappaN3,kappaN6,kappaN9,kappaN15,kappaO3,kappaO6,kappaO9)gadolinium OriginatorGuerbet ClassDiagnostic agents; Gadolinium-containing contrast agents; Macrocyclic compounds; Propylamines; Pyridines Mechanism of ActionMagnetic resonance imaging enhancers RegisteredCNS disorders Phase IIIUnspecified Phase IILiver cancer 21 Sep …
Category «APPROVALS 2022»
Eflapegrastim
It’s only fair to share… Eflapegrastim エフラペグラスチム; Molecular Formula C15-H28-N2-O6(C2-H4-O)n Molecular Weight 376.4468 Formula C3070H4764N806O927S23.(C2H4O)n UNII: UT99UG9QJX HM10460A SPI-2012 HNK460 Reducing neutropenia and the incidence of infecton in patients with cancer (2S)-1-{3-[2-(3-{[(1S,2R)-1-carboxy-2-hydroxypropyl]amino}propoxy)ethoxy]propyl}pyrrolidine-2-carboxylic acid APPROVED FDA 2022/9/9, Rolvedon CAS: 1384099-30-2 LAPS-GCSF, ROLONTIS Antineutropenic, Leukocyte growth factor Poly(oxy-1,2-ethanediyl), α-hydro-ω-hydroxy-, 1-ether with immunoglobulin G4 [1-[1-(3-hydroxypropyl)proline]] (human Fc fragment), (3→3′)–disulfide with immunoglobulin G4 …
Terlipressin acetate
It’s only fair to share… Terlipressin acetate テルリプレシン酢酸塩 C52H74N16O15S2. (C2H4O2)x CAS: 914453-96-6 ACETATEFREE FORM 14636-12-5 Terlipressin acetate (JAN); Heamopressin (TN); Terlivaz (TN) Cardiovascular agent Antidiuretic, Vasoconstrictor, Arginine vasopressin receptor agonist USFDA APPROVED 2022/9/14 An inactive peptide prodrug that is slowly converted in the body to lypressin. It is used to control bleeding of ESOPHAGEAL VARICES and …
Betibeglogene autotemcel
It’s only fair to share… Betibeglogene autotemcel ベチベグロゲンアウトテムセル 2022/8/17, FDA APPROVED Zynteglo Cellular therapy product Treatment of betathalassemia BB305 LVV, bb 1111 BB305 transduced SCD CD34+ HSCs bb1111 LentiGlobin BB305 LVV-transduced autologous SCD CD34+ HSCs bb1111 LentiGlobin drug product for SCD LentiGlobin drug product for sickle cell disease LentiGlobin for SCD bb1111 Betibeglogene autotemcel, sold under …
Spesolimab
It’s only fair to share… (Heavy chain) QVQLVQSGAE VKKPGASVKV SCKASGYSFT SSWIHWVKQA PGQGLEWMGE INPGNVRTNY NENFRNKVTM TVDTSISTAY MELSRLRSDD TAVYYCTVVF YGEPYFPYWG QGTLVTVSSA STKGPSVFPL APSSKSTSGG TAALGCLVKD YFPEPVTVSW NSGALTSGVH TFPAVLQSSG LYSLSSVVTV PSSSLGTQTY ICNVNHKPSN TKVDKRVEPK SCDKTHTCPP CPAPEAAGGP SVFLFPPKPK DTLMISRTPE VTCVVVDVSH EDPEVKFNWY VDGVEVHNAK TKPREEQYNS TYRVVSVLTV LHQDWLNGKE YKCKVSNKAL PAPIEKTISK AKGQPREPQV YTLPPSREEM TKNQVSLTCL VKGFYPSDIA VEWESNGQPE NNYKTTPPVL DSDGSFFLYS KLTVDKSRWQ QGNVFSCSVM HEALHNHYTQ KSLSLSPGK (Light chain) QIVLTQSPGT …
Lenacapavir sodium
It’s only fair to share… Lenacapavir sodium レナカパビルナトリウム Formula C39H31ClF10N7O5S2. Na C39H32ClF10N7O5S2 FREE FORM CAS 2283356-12-5 2189684-44-2 FEE FORM Mol weight 990.2641 968.28 FREE FORM 2022/8/17 EMA APPROVED, SUNLECA N-[(1S)-1-[3-[4-chloro-3-(methanesulfonamido)-1-(2,2,2-trifluoroethyl)indazol-7-yl]-6-(3-methyl-3-methylsulfonylbut-1-ynyl)pyridin-2-yl]-2-(3,5-difluorophenyl)ethyl]-2-[(2S,4R)-5,5-difluoro-9-(trifluoromethyl)-7,8-diazatricyclo[4.3.0.02,4]nona-1(6),8-dien-7-yl]acetamide Treatment of HIV-1 infection PF-3540074, to GS-CA1, GS-6207 GS-HIV GS-CA1 GS-CA2 Lenacapavir, sold under the brand name Sunlenca, is a medication used to treat HIV/AIDS.[1] It is taken by mouth or by subcutaneous injection.[1] …
OTERACIL POTTASIUM
It’s only fair to share… OTERACIL UNII4R7FFA00RX, CAS Number2207-75-2, WeightAverage: 195.175, Monoisotopic: 194.96823705, Chemical FormulaC4H2KN3O4 [K+].OC1=NC(=NC(=O)N1)C([O-])=O 1,3,5-Triazine-2-carboxylic acid, 1,4,5,6-tetrahydro-4,6-dioxo-, potassium salt (1:1) 218-627-5 [EINECS] 2207-75-2 [RN] 4,6-Dihydroxy-1,3,5-triazine-2-carboxylic acid potassium salt KOX NSC 28841 Oxonate Oxonate, potassium CDSCO APPROVED,01.02.2022 Gimeracil bulk & Oteracil potassium bulk and Tegafur 15mg/20mg, Gimeracil 4.35mg/5.8mg and Oteracil 11.8mg/15.8mg capsules indicated in adults for the treatment …
GIMERACIL
It’s only fair to share… GIMERACIL C5H4ClNO2, 145.54 103766-25-2 5-chloro-4-hydroxy-1H-pyridin-2-one 5-Chloro-2,4-dihydroxypyridine 5-chloropyridine-2,4-diol 5-Chloro-4-hydroxy-2(1H)-pyridone Ts-1 (TN) CCDSCO APPROVED,01.02.2022 Gimeracil bulk & Oteracil potassium bulk and Tegafur 15mg/20mg, Gimeracil 4.35mg/5.8mg and Oteracil 11.8mg/15.8mg capsules indicated in adults for the treatment of advanced gastric cancer when given in combination with cisplatin. Tegafur/gimeracil/oteracil Combination of Tegafur Antineoplastic drug Gimeracil …
Darinaparsin
It’s only fair to share… SVG Image IUPAC Condensed H-gGlu-Cys(Unk)-Gly-OH Sequence XXG Darinaparsin ダリナパルシン , Darvias JAPAN 2022 APPROVED, PMDA 2022/6/20 (2S)-2-amino-5-[[(2R)-1-(carboxymethylamino)-3-dimethylarsanylsulfanyl-1-oxopropan-2-yl]amino]-5-oxopentanoic acid (S)-2-amino-5-(((R)-1-((carboxymethyl)amino)-3-((dimethylarsino)thio)-1-oxopropan-2-yl)amino)-5-oxopentanoic acid Glycine, L-gamma-glutaMyl-S-(diMethylarsino)-L-cysteinyl- Formula C12H22AsN3O6S CAS 69819-86-9 Mol weight 411.3062 Efficacy Antineoplastic Comment organic arsenical Zinapar, ZIO-101, DMAs(III)G, clarinaparsin, UNII-9XX54M675G, SP-02L OriginatorTexas A&M University; University of Texas M. D. Anderson Cancer Center DeveloperSolasia Pharma; ZIOPHARM Oncology ClassAmines; Antineoplastics; …
Pimitespib
It’s only fair to share… Pimitespib TAS 116 CAS 1260533-36-5 Antineoplastic, Hsp 90 inhibitor 3-ethyl-4-[4-[4-(1-methylpyrazol-4-yl)imidazol-1-yl]-3-propan-2-ylpyrazolo[3,4-b]pyridin-1-yl]benzamide Pimitespib (TAS-116) is an oral bioavailable, ATP-competitive, highly specific HSP90α/HSP90β inhibitor (Kis of 34.7 nM and 21.3 nM, respectively) without inhibiting other HSP90 family proteins such as GRP94. Pimitespib demonstrates less ocular toxicity. Formula C25H26N8O CAS 1260533-36-5 Mol weight 454.5269 JAPAN APPROVED 2022/6/20, ピミテスピブ Jeselhy …