Category «Uncategorized»

Idasanutlin, RG-7388, идасанутлин ,إيداسانوتلين , 依达奴林

It’s only fair to share… Idasanutlin(RG-7388) cas     1229705-06-9 идасанутлин [Russian] إيداسانوتلين [Arabic] 依达奴林 [Chinese] 4-{ [(2R,3S,4R,5S)-4-(4-Chloro-2-fluoro-phenyl)-3-(3-chloro-2-fluoro-phenyl)-4-cyano-5-(2,2- dimethyl-prop yl)-pyrrolidine-2-carbonyl] -amino }-3-methoxy-benzoic acid (C31H29Cl2F2N304) 4-{[(2R,3S,4R,5S)-4-(4-Chloro-2-fluoro-phenyl)-3-(3-chloro-2-fluoro-phenyl)-4-cyano-5-(2,2-dimethyl-propyl)-pyrrolidine-2-carbonyl]-amino}-3-methoxy-benzoic acid MW 616.4973 F. Hoffmann-La Roche Ag, Hoffmann-La Roche Inc.ROCHE PHASE1 for the oral treatment of cancer, including solid tumors and hematological tumors, including acute myelogenous leukemia Acute myelogenous leukemia; Cancer; Prostate …

Glenmark Pharmaceuticals celebrates 39th annual day at The Lalit Hotel, Mumbai, India

It’s only fair to share… At Glenmark Pharmaceuticals 39th annual day at The Lalit Hotel, Mumbai, India, Received 10 yrs long service recognition from Mrs Cheryl pinto, coowner, Director, Corporate, HR, Glenmark Pharmaceuticals Ltd, Followed by gala evening with dance and fun With Mr Glenn saldanha, owner, CEO, and MD of Glenmark pharmaceuticals, He spoke …

SUGAMMADEX (Org 25969, Bridion)

It’s only fair to share… SUGAMMADEX CAS number 343306-71-8 Weight Average: 2002.12 Monoisotopic: 2000.408874758 Chemical Formula C72H112O48S8 WATCH OUT POST WILL BE UPDATED……… SUGAMMADEX 343306-71-8 cas  free Sugammadex sodium 343306-79-6 MF: C72H104O48S8.8Na MW: 2178.01 Bridion; UNII-ERJ6X2MXV7; Suγdex Sodium; Suγdex; 343306-79-6; Org 25969; Sugammadex, Org25969; Org-25969; Org 25969; 361LPM2T56 Sugammadex (Org 25969, Bridion) is chemically known as Cyclooctakis-(l-→4)-[6-S-(2-carboxyethyl)-6-thio-a-D-glucopyranosyl]. …

ACS INDUSTRY SYMPOSIUM , RECENT ADVANCES IN DRUG DEVELOPMENT HYDERABAD, INDIA, Dr. REDDYS, Nov 11-12 2016

It’s only fair to share… GROUP PICTURE Inaugural ACS Industry Symposium, 11-12 November 2016 in Hyderabad, India Recent Advances in Drug Development ACS2016 ACS Symposium at Dr. Reddy’s Hyderabad, India, Nov 11-12 2016 ACS INDUSTRY SYMPOSIUM , RECENT ADVANCES IN DRUG DEVELOPMENT HYDERABAD, INDIA, http://acssymposium.org.in/  The American Chemical Society (ACS) hosted the inaugural ACS Industry Symposium …

Acetylcholine Chloride

It’s only fair to share… Acetylcholine Chloride 2-acetyloxyethyl(trimethyl)azanium;chloride 60-31-1 Molecular Formula: C7H16ClNO2 Molecular Weight: 181.66 g/mol Acetylcholine chloride is obtained as white or off-white hygroscopic crystals, or as a crystalline powder. The salt is odorless, or nearly odorless, and is a very deliquescent powder. Acetylcholine bromide is obtained as deliquescent crystals, or as a white …

Valdetamide

It’s only fair to share… CAS Registry Number: 512-48-1 CAS Name: 2,2-Diethyl-4-pentenamide Additional Names: diethylallylacetamide Trademarks: Novonal (Hoechst) Molecular Formula: C9H17NO Molecular Weight: 155.24 Percent Composition: C 69.63%, H 11.04%, N 9.02%, O 10.31% Literature References: Description: Bockmühl, Schaumann, Dtsch. Med. Wochenschr. 54, 270 (1928). Pharmacokinetics and metabolism: H. Uehleke, M. Brinkschulte-Freitas, Arch. Pharmacol. 302, 11 (1978). TLC determn in urine: E. Klug, P. Toffel, Arzneim.-Forsch. 29, 1651 (1979). Properties: White powder, mp …

PF 06273340

It’s only fair to share… PF-06273340 N-(5-(2-amino-7-(1-hydroxy-2-methylpropan-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)pyridin-3-yl)-2-(5-chloropyridin-2-yl)acetamide CAS 1402438-74-7 Chemical Formula: C23H22ClN7O3 Molecular Weight: 479.925 Originator Pfizer ClassAnalgesics; Small molecules Mechanism of ActionUndefined mechanism 06 Oct 2014 Pfizer plans a phase I trial in Pain (In volunteers) in the Netherlands (NCT02260947) 07 Aug 2014 Discontinued – Phase-I for Pain (In volunteers) in Belgium (PO) 07 Aug 2014 Discontinued – …

BRD 2879

It’s only fair to share… BRD2879 BRD-K56962879-001-01-5 CAS 1304750-47-7 Chemical Formula: C30H38FN3O5S Molecular Weight: 571.7084 3-cyclohexyl-1-(((4R,5R)-8-((3-fluorophenyl)ethynyl)-2-((S)-1-hydroxypropan-2-yl)-4-methyl-1,1-dioxido-2,3,4,5-tetrahydrobenzo[b][1,4,5]oxathiazocin-5-yl)methyl)-1-methylurea 3-cyclohexyl-1-[[(4R,5R)-8-[2-(3-fluorophenyl)ethynyl]-2-[(2S)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^{6},2-benzoxathiazocin-5-yl]methyl]-1-methylurea BRD2879 is a potent and cell-active inhibitor of IDH1-R132H with a markedly different structure from previously reported probes with (IC50 = 50 nM for inhibiting IDH1-R132H enzyme). BRD2879 represents a new structural class of mutant IDH1 inhibitors that, …