It’s only fair to share… Ciltacabtagene autoleucel FDA APPROVED, 2022/2/28, Carvykti Treatment of multiple myeloma JNJ-68284528 LCAR-B38M CAR-T cells Ciltacabtagene autoleucel is a BCMA-directed CAR T-cell therapy used in the treatment of relapsed or refractory multiple myeloma in previously treated patients. U.S. FDA Approves CARVYKTI™ (ciltacabtagene autoleucel), Janssen’s First Cell Therapy, a BCMA-Directed CAR-T …
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TRIAMCINOLONE
It’s only fair to share… TRIAMCINOLONE Molecular FormulaC21H27FO6 Average mass394.434 Da (11β,16α)-9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione (8S,9R,10S,11S,13S,14S,16R,17S)-9-Fluor-11,16,17-trihydroxy-17-(hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-on (8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11,16,17-trihydroxy-17-(hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one (8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11,16,17-trihydroxy-17-(hydroxyacétyl)-10,13-diméthyl-6,7,8,9,10,11,12,13,14,15,16,17-dodécahydro-3H-cyclopenta[a]phénanthrén-3-one (8S,9R,10S,11S,13S,14S,16R,17S)-9-Fluoro-17-glycoloyl-11,16,17-trihydroxy-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one 124-94-7 [RN] 16a-Hydroxy-9a-fluoroprednisolone 1ZK20VI6TY 204-718-7 [EINECS] 755 9a-Fluoro-16a-hydroxyprednisolone TU3850000 トリアムシノロン[Japanese] 去炎松[Chinese] Triamcinolone CAS Registry Number: 124-94-7 CAS Name: (11b, 16a)-9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione Additional Names: D1-9a-fluoro-16a-hydroxyhydrocortisone; 9a-fluoro-16a-hydroxyprednisolone; D1-16a-hydroxy-9a-fluorohydrocortisone; 16a-hydroxy-9a-fluoroprednisolone Manufacturers’ Codes: CL-19823 Trademarks: Aristocort (Lederle); Kenacort (BMS); Ledercort (tabl.) (Lederle); Omcilon (BMS); Tricortale (Bergamon); Volon (BMS) Molecular Formula: C21H27FO6, Molecular Weight: 394.43 Percent …
Ensitrelvir
It’s only fair to share… Ensitrelvir S-217622, S 217622, Xocova, SHIONOGI, 6-[(6-chloro-2-methylindazol-5-yl)amino]-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-1-[(2,4,5-trifluorophenyl)methyl]-1,3,5-triazine-2,4-dione CAS 2647530-73-0 C22H17ClF3N9O2531.9 Synonyms BDBM513874 bioRxiv20220126.477782, S-217622 Ensitrelvir fumarateCAS No. : 2757470-18-9 C22 H17 Cl F3 N9 O2 . C4 H4 O4 1,3,5-Triazine-2,4(1H,3H)-dione, 6-[(6-chloro-2-methyl-2H-indazol-5-yl)imino]dihydro-3-[(1-methyl-1H-1,2,4-triazol-3-yl)methyl]-1-[(2,4,5-trifluorophenyl)methyl]-, (6E)-, (2E)-2-butenedioate (1:1) Formula: C26H21ClF3N9O6 M. Wt. : 647.95 FDA 2026, APPROVALS 2026, 5/29/2026, Xocova To use as post-exposure prophylaxis of coronavirus disease 2019 (COVID-19) following contact with an …
RADOTINIB
It’s only fair to share… RADOTINIB Molecular FormulaC27H21F3N8O Average mass530.504 Da 4-Methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-{[4-(2-pyrazinyl)-2-pyrimidinyl]amino}benzamide 4-methyl-N-[3-(4-methylimidazole-l-yl)-5-trifluoromethyl-phenyl] – 3-(4-pyrazine-2-yl-pyrimidine-2-yl amino)benzamide 9242 926037-48-1 [RN] 926037-48-1 (Radotinib); 926037-85-6 (Radotinib 2HCl); Benzamide, 4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(2-pyrazinyl)-2-pyrimidinyl]amino]- I284LJY110, IY5511 UNII-I284LJY110 радотиниб رادوتينيب 雷度替尼 MOA：Bcr-Abl tyrosine kinase inhibitor Indication：Chronic myeloid leukemia (CML ) Company：IL-Yang (Originator) IY-5511; IY-5511A3001 Approval Date Approval Type Trade Name Indication Dosage Form Strength Company Review Classification …
Cyclobenzaprine
It’s only fair to share… Cyclobenzaprine Molecular FormulaC20H21N Average mass275.387 Da MK-130 TNX-102 1-(3-Dimethylaminopropylidene)-2,3:6,7-dibenzo-4-suberene 1-Propanamine, 3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl- [ACD/Index Name] 206-145-8 [EINECS] 3-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine 303-53-7 [RN] 5-(3-Dimethylaminopropylidene)dibenzo[a,e]cycloheptatriene циклобензаприн [Russian] [INN] سيكلوبنزابرين [Arabic] [INN] 环苯扎林 [Chinese] [INN] Cyclobenzaprine, CAS Registry Number: 303-53-7 CAS Name: 3-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine Additional Names: N,N-dimethyl-5H-dibenzo[a,d]cyclohepten-D5,g-propylamine; 5-(3-dimethylaminopropylidene)dibenzo[a,e]cycloheptatriene; 1-(3-dimethylaminopropylidene)-2,3:6,7-dibenzo-4-suberene; proheptatriene Manufacturers’ Codes: MK-130; Ro-4-1577; RP-9715 Molecular Formula: C20H21N, Molecular Weight: 275.39 Percent Composition: C 87.23%, H 7.69%, N 5.09% Literature References: Prepn: GB 858187 (1961 to Hoffmann-La Roche); Villani et al., J. …
Pyritinol
It’s only fair to share… Pyritinol Molecular FormulaC16H20N2O4S2 Average mass368.471 Da 1098-97-1 [RN] 1308 214-150-1 [EINECS] 233-178-5 [EINECS] 3,3′-[Dithiobis(methylene)]bis[5-hydroxy-6-methyl-4-pyridinemethanol] 4-Pyridinemethanol, 3,3′-[dithiobis(methylene)]bis[5-hydroxy-6-methyl- пиритинол [Russian] [INN] بيريتينول [Arabic] [INN] 吡硫醇 [Chinese] [INN] Pyritinol, CAS Registry Number: 1098-97-1 CAS Name: 3,3¢-[Dithiobis(methylene)]bis[5-hydroxy-6-methyl-4-pyridinemethanol] Additional Names: bis(4-hydroxymethyl-5-hydroxy-6-methyl-3-pyridylmethyl) disulfide; bis[(3-hydroxy-4-hydroxymethyl-2-methyl-5-pyridyl)methyl] disulfide; dipyridoxolyldisulfide; pyridoxine-5-disulfide; pyrithioxin Molecular Formula: C16H20N2O4S2, Molecular Weight: 368.47 Percent Composition: C 52.15%, H 5.47%, N 7.60%, O 17.37%, S 17.40% Literature References: Prepn: Zima, Schorre, US 3010966 (1961 to E. Merck); Iwanami et …
Liranaftate
It’s only fair to share… Liranaftate リラナフタート 88678-31-3 (6-Methoxy-2-pyridinyl)methylcarbamothioic Acid O-(5,6,7,8-Tetrahydro-2-naphthalenyl) Ester O-(5,6,7,8-Tetrahydronaphthalen-2-yl) (6-methoxypyridin-2-yl)methylcarbamothioate Zefnart;Piritetrate;M-732 лиранафтат ليرانافتات 利拉萘酯 Formula C18H20N2O2S CAS 88678-31-3 Mol weight 328.4286 Efficacy Antifungal, Ergosterol biosynthesis inhibitor Comment Thiocarbamate Liranaftate (trade name Zefnart) is a topical antifungal drug.[1] It is used as a 2% cream used to treat tinea pedis (athlete’s foot), tinea corporis (ringworm), and tinea cruris (jock itch).[2] It was approved for use …
Fabomotizole
It’s only fair to share… Fabomotizole Afobazole Molecular FormulaC15H21N3O2S Average mass307.411 Da 0F8K1X115C 173352-21-1 [RN], 173352-21-1 (free base) 173352-39-1 (HCl) 189638-30-0 (2HCl) 1H-Benzimidazole, 6-ethoxy-2-[[2-(4-morpholinyl)ethyl]thio]- Obenoxazine, Afobazol, Afobazole, Aphobazole, Fabomotizole dihydrochloride, CM-346, CM346, CM 346, фабомотизол[Russian][INN] فابوموتيزول[Arabic][INN] 法莫替唑[Chinese][INN] Fabomotizole dihydrochloride CAS#: 189638-30-0 (2HCl) Chemical Formula: C15H23Cl2N3O2SMolecular Weight: 380.33 Fabomotizole (also known as Afobazole) is a selective non-benzodiazepine anxiolytic which was …
ARTEMETHER
It’s only fair to share… ARTEMETHER Molecular FormulaC16H26O5 Average mass298.375 Da (3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-methoxy-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene (4S,5R,8S,9R,10S,12R,13R)-10-Methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecane [ 3,12-Epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin, decahydro-10-methoxy-3,6,9-trimethyl-, (3R,5aS,6R,8aS,9R,10S,12R,12aR)- 3,12-Epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin, decahydro-10-methoxy-3,6,9-trimethyl-, (5aS,6R,8aS,9R,10S,12R,12aR)- 71963-77-4 [RN] dihydroartemisinin methyl ether Dihydroqinghaosu Methyl Ether KD4165000 PALUTHER SM 224 SM-224 3,12-Epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin, decahydro-10-methoxy-3,6,9-trimethyl-, [3R-(3α,5aβ,6β,8aβ,9α,10α,12β,12aR*)]- (3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-10-methoxy-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin (+)-Artemether Artemether CAS Registry Number: 71963-77-4 CAS Name: (3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-10-methoxy-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin Additional Names: dihydroartemisinin methyl ether; dihydroqinghaosu methyl ether; o-methyldihydroartemisinin Manufacturers’ Codes: SM-224 Trademarks: Paluther (RPR) Molecular Formula: C16H26O5, Molecular …
Lumefantrine
It’s only fair to share… lumefantrine Molecular FormulaC30H32Cl3NO Average mass528.940 Da UNIIF38R0JR742 CAS number82186-77-4 (±)-2-(Dibutylamino)-1-((9Z)-2,7-dichloro-9-(4-chlorobenzylidene)-9H-fluoren-4-yl)ethanol (±)-2,7-Dichloro-9-((Z)-p-chlorobenzylidene)-α-((dibutylamino)methyl)fluorene-4-methanol (9Z)-2,7-Dichloro-9-[(4-chlorophenyl)methylene]-α-[(dibutylamino)methyl]-9H-fluorene-4-methanol 120583-70-2 [RN] 120583-71-3 [RN] 2-(dibutylamino)-1-[(9Z)-2,7-dichloro-9-[(4-chlorophenyl)methylidene]-9H-fluoren-4-yl]ethan-1-ol (±)-2,7-Dichloro-9-((Z)-p-chlorobenzylidene)-α-((dibutylamino)methyl)fluorene-4-methanol 2-Dibutylamino-1-[2,7-dichloro-9-(4-chloro-benzylidene)-9H-fluoren-4-yl]-ethanol 2-Dibutylamino-1-{2,7-dichloro-9-[1-(4-chloro-phenyl)-meth-(Z)-ylidene]-9H-fluoren-4-yl}-ethanol Benflumetol dl-Benflumelol UNII F38R0JR742 CAS number 82186-77-4 Weight Average: 528.94 Monoisotopic: 527.154947772 Chemical Formula C30H32Cl3NO Lumefantrine, also known as HSDB 7210, is an antimalarial agent used to treat acute uncomplicated malaria. …