Category «Uncategorized»

Amantadine Hydrochloride, アダマンタン-1-アミン

It’s only fair to share… Amantadine Molecular Formula C10H17N Average mass 151.249 Da [768-94-5] 1-ADAMANTAMINE 1-adamantanamine; 1-adamantylamine; 1-aminoadamantane; Amantidine; Aminoadamantane 1-Adamantylamine 1-Aminotricyclo(3.3.1.1(sup 3,7))decane 2204333 [Beilstein] 31377-23-8 [RN] 40933-03-7 [RN] 4-pyridinecarboxylic acid, compd. with tricyclo[3.3.1.13,7]decan-1-amine (1:1) Journal of the American Chemical Society, 91, p. 6457, 1969 DOI: 10.1021/ja01051a047 Synthesis, p. 457, 1976 AMANTADINE HYDROCHLORIDE Molecular FormulaC10H18ClN Average mass187.710 Da CAS 665-66-7 SPECTROSCOPY BASE 13 …

JTV 519, K 201

It’s only fair to share… JTV-519 Molecular FormulaC25H32N2O2S Average mass424.599 Da 145903-06-6 CAS   JTV-519 hydrochloride salt Molecular FormulaC25H33ClN2O2S Average mass461.060 Da 3-(4-Benzyl-1-piperidinyl)-1-(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)-1-propanonhydrochlorid (1:1) 4-[3-(4-benzylpiperidin-1-yl)propanoyl]-7-methoxy-2,3,4,5-tetrahydro-1,4-benzothiazepine hydrochloride JTV-519 hydrochloride salt 1038410-88-6 [RN] UNII-0I621Y6R4Q K201 1038410-88-6 K 201 SCHEMBL194018 CHEMBL2440857 DTXSID90146108 0I621Y6R4Q LS-193564 JAPAN TOBACCO Acute Myocardial Infarction, Treatment of Cardiovascular Diseases (Not Specified) Antiarrhythmic Drugs JTV-519 (K201) is a 1,4-benzothiazepine derivative …

Phytomenadione, Phytonadione, фитоменадион ,فيتوميناديون ,

It’s only fair to share… Phytomenadione, PHYTONADIONE, Phylloquinone Molecular Formula: C31H46O2 Molecular Weight: 450.707 g/mol [R-[R*,R*-(E)]]-2-Methyl-3-(3,7,11,15-tetramethyl-2-hexadecenyl)-1,4-naphthalenedione 1,4-Naphthalenedione, 2-methyl-3-((2E,7R,11R)-3,7,11,15-tetramethyl-2-hexadecenyl)- 2′,3′-trans-Vitamin K1 фитоменадион [Russian] [INN] فيتوميناديون [Arabic] [INN] 2-methyl-3-[(2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-yl]naphthalene-1,4-dione  CAS 84-80-0[RN] Antihemorrhagic vitamin Aqua mephyton AQUAMEPHYTON Combinal K1 Kativ N Kephton Kinadion K-Ject KONAKION Mono-kay Phyllochinonum Phylloquinone (8CI) Optical Rotatory Power -0.28 ° Solv: 1,4-dioxane (123-91-1); Wavlen: 589.3 nm; Temp: 25 °C Karrer, …

ELAMIPRETIDE

It’s only fair to share… Elamipretide H-D-Arg-Tyr(2,6-diMe)-Lys-Phe-NH2 D-arginyl-2,6-dimethyl-L-tyrosyl-L-lysyl-L-phenylalaninamide (2S)-6-amino-2-[[(2S)-2-[[(2R)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-N-[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]hexanamide CAS 736992-21-5 Chemical Formula: C32H49N9O5 Molecular Weight: 639.8 A free radical scavenger and antioxidant that localizes in the inner mitochondrial membrane. Mitochondrial Protective Agent to Improve Cell Viability Elamipretide bendavia UNII-87GWG91S09 736992-21-5 MTP 131 RX 31 SS 31 87GWG91S09 L-Phenylalaninamide, D-arginyl-2,6-dimethyl-L-tyrosyl-L-lysyl- SS-31 peptide Arg-Dmt-Lys-Phe-NH2 D-Arg-Dmt-Lys-Phe-NH2 SS31 peptide …

A highly efficient Suzuki-Miyaura methylation of pyridines leading to the drug pirfenidone and its CD3 version (SD-560)

It’s only fair to share…   A highly efficient Suzuki-Miyaura methylation of pyridines leading to the drug pirfenidone and its CD3 version (SD-560) Green Chem., 2017, Advance Article DOI: 10.1039/C7GC01740E, Communication Eliezer Falb, Konstantin Ulanenko, Andrey Tor, Ronen Gottesfeld, Michal Weitman, Michal Afri, Hugo Gottlieb, Alfred Hassner The first methylation/deuteromethylation in green and nearly quantitative …

Development of a General Protocol To Prepare 2H-1,3-Benzoxazine Derivatives

It’s only fair to share… 2H-1,3-Benzoxazine natural products and related bioactive molecules.   4-(2-Bromo-5-chlorobenzyl)-7-chloro-2-phenyl-2H-benzo[e][1,3]oxazine 2 as a light-yellow solid (82% yield). 1H NMR (500 MHz, CDCl3): δ (ppm) 7.55–7.52 (m, 3H), 7.42–7.34 (m, 3H), 7.30 (d, 1H, J = 3.5 Hz,) 7.29 (s, 1H), 7.12 (dd, 1H, J = 8.5 Hz, 2.5 Hz), 6.95–6.91 (m, 2H), 6.57 (1H, s), 4.16 (ABq, …

Xanomeline (LY-246,708; Lumeron, Memcor) ксаномелин , كسانوميلين , 诺美林 ,

It’s only fair to share… Xanomeline (LY-246,708; Lumeron, Memcor) CAS 131986-45-3 Molecular FormulaC14H23N3OS Average mass281.417 Da ксаномелин , كسانوميلين , 诺美林 ,  Hexyloxy-TZTP 5-[4-(Hexyloxy)-1,2,5-thiadiazol-3-yl]-1-méthyl-1,2,3,6-tétrahydropyridine Xanomeline(LY246708) is a selective M1 muscarinic receptor agonist. Pyridine, 3-[4-(hexyloxy)-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methyl- Xanomeline(LY246708) is a selective M1 muscarinic receptor agonist. in vitro: Xanomeline had high affinity for muscarinic receptors in brain homogenates, but had substantially less or no affinity for a number …

Diethyl Chlorophosphate

It’s only fair to share…   Diethyl Chlorophosphate (CAS no 814–49–3)(15) Preparative Procedure In a dry four-neck 250 mL round-bottom flask equipped with a mechanical stirrer, a thermometer, and an argon inlet were introduced at 20 °C triethylamine (21.3 g, 210 mmol), tert-butyl methyl ether (75 mL), and ethanol (9.67 g, 210 mmol). Phosphorus oxychloride (15.3 …

CARMUSTINE

It’s only fair to share… CARMUSTINE Molecular Formula: C5H9Cl2N3O2 Molecular Weight: 214.046 g/mol CAS 154-93-8 Brain tumor; Hodgkins disease; Multiple myeloma; Non-Hodgkin lymphoma 1,3-bis(2-chloroethyl)-3-nitrosourea Urea, 1,3-bis(2-chloroethyl)-1-nitroso- (8CI) N,N’-Bis(2-chloroethyl)-N-nitrosourea 1,3-Bis(2-chlorethyl)-1-nitrosourea 1,3-Bis(2-chloroethyl)-1-nitrosourea 1,3-Bis(2-chloroethyl)nitrosourea 1,3-Bis(β-chloroethyl)-1-nitrosourea BCNU Becenun BiCNU Carmubris Carmustin Carmustine DTI 015 FDA 0345 Gliadel Gliadel Wafer NSC 409962 Nitrumon SK 27702 SRI 1720 Title: Carmustine CAS Registry Number: 154-93-8 …