It’s only fair to share… Tebentafusp-tebn IMCGP100 UNIIN658GY6L3E CAS number1874157-95-5 FDA APPROVED 1/25/2022, Kimmtrak, To treat unresectable or metastatic uveal melanoma Immunocore Limited T cell receptor α chain (synthetic human) fusion protein with T cell receptor β chain (synthetic human) fusion protein with immunoglobulin, anti-(human CD3 antigen) (synthetic scFv fragment) Protein Sequence Sequence Length: 695, 500, 195 Sequence: …
VIP 152, BAY 1251152
It’s only fair to share… VIP 152, BAY 1251152 CAS RN.: 1610358-56-9 C19H18F2N4O2S 5-fluoro-4-(4-fluoro-2-methoxyphenyl)-N-[4-[(methylsulfonimidoyl)methyl]pyridin-2-yl]pyridin-2-amine 2-Pyridinamine, 5-fluoro-4-(4-fluoro-2-methoxyphenyl)-N-[4-[(S-methylsulfonimidoyl)methyl]-2-pyridinyl]-, (+)- (+)-BAY-1251152 is a CDK9 inhibitor extracted from patent WO 2014076091 A1, example 1. RN: 1610408-97-3 UNII: 1255AT22ZJ UNII-1255AT22ZJ 2-Pyridinamine, 5-fluoro-4-(4-fluoro-2-methoxyphenyl)-N-[4-[[[S(S)]-S-methylsulfonimidoyl]methyl]-2-pyridinyl]- Molecular Formula, C19-H18-F2-N4-O2-S, Molecular Weight, 404.4336 OriginatorBayer DeveloperBayer; Vincerx Pharma ClassAntineoplastics; Fluorinated hydrocarbons; Organic sulfur compounds; Phenyl ethers; Pyridines; Small molecules …
Gefapixant citrate
It’s only fair to share… Gefapixant Molecular FormulaC14H19N5O4S Average mass353.397 Da 1015787-98-0 [RN] 10642 AF 217 5-[(2,4-Diamino-5-pyrimidinyl)oxy]-4-isopropyl-2-methoxybenzenesulfonamide 5-(2,4-diamino-pyrimidin-5-yloxy)-4-isopropyl-2-methoxy-benzene- sulfonamide Gefapixant Citrate Formula C14H19N5O4S. C6H8O7 CAS 2310299-91-1 Mol weight 545.5203 APPROVED JAPAN PMDA 2022/1/20, Lyfnua ゲーファピキサントクエン酸塩 吉法匹生 Efficacy Analgesic, Anti-inflammatory, Antitussive, P2X3 receptor antagonist Comment Treatment of disorders associated with purinergic receptor activation Gefapixant (MK-7264) is a drug which acts …
Fluphenazine
It’s only fair to share… Fluphenazine Molecular FormulaC22H26F3N3OS Average mass437.522 Da SQ 10733 Squibb 16144 UNIIS79426A41Z CAS number69-23-8 Product Ingredients INGREDIENT UNII CAS INCHI KEY Fluphenazine decanoate FMU62K1L3C 5002-47-1 VIQCGTZFEYDQMR-UHFFFAOYSA-N Fluphenazine enanthate QSB34YF0W9 2746-81-8 LRWSFOSWNAQHHW-UHFFFAOYSA-N Fluphenazine hydrochloride ZOU145W1XL 146-56-5 MBHNWCYEGXQEIT-UHFFFAOYSA-N 2-(Trifluoromethyl)-10-[3-[1-(b-hydroxyethyl)-4-piperazinyl]propyl]phenothiazine 200-702-9 [EINECS] 4-(3-(2-(trifluoromethyl)phenothiazin-10-yl)propyl)-1-Piperazineethanol 4-[3-[2-(Trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-1-piperazineethanol 69-23-8 [RN] فلوفينازين[Arabic][INN] 氟奋乃静[Chinese][INN] 1-(2-Hydroxyethyl)-4-[3-(trifluoromethyl-10-phenothiazinyl)propyl]piperazine 10-[3′-[4”-(b-Hydroxyethyl)-1”-piperazinyl]propyl]-3-trifluoromethylphenothiazine 1-Piperazineethanol, 4-(3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)propyl)- 1-Piperazineethanol, 4-[3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl]- read https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/071413s019lbl.pdf …
ADAPALENE
It’s only fair to share… ADAPALENE Molecular FormulaC28H28O3 Average mass412.520 Da CD 271 CD-271 CD-271, Differin, Differine 106685-40-9 [RN] 2-Naphthalenecarboxylic acid, 6-(4-methoxy-3-tricyclo[3.3.1.13,7]dec-1-ylphenyl)- 6-[3-(Adamantan-1-yl)-4-methoxyphenyl]-2-naphthoic acid 6-[4-methoxy-3-(tricyclo[3.3.1.13,7]dec-1-yl)phenyl]naphthalene-2-carboxylic acid Adapalene CAS Registry Number: 106685-40-9 CAS Name: 6-(4-Methoxy-3-tricyclo[3.3.1.13,7]dec-1-ylphenyl)-2-naphthalenecarboxylic acid Additional Names: 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid Manufacturers’ Codes: CD-271 Trademarks: Differin (Galderma) Molecular Formula: C28H28O3 Molecular Weight: 412.52 Percent Composition: C 81.52%, H 6.84%, O 11.64% Literature References: Retinoid selective for retinoic …
Fam-trastuzumab deruxtecan-nxki
It’s only fair to share… Fam-trastuzumab deruxtecan-nxki Formula C6460H9972N1724O2014S44. (C52H57FN9O13)8 CAS 1826843-81-5 Mol weight 153701.9811 Antineoplastic Disease Breast cancer (HER2 positive) DS-8201a Trastuzumab deruxtecan, sold under the brand name Enhertu, is an antibody-drug conjugate consisting of the humanized monoclonal antibody trastuzumab (Herceptin) covalently linked to the topoisomerase I inhibitor deruxtecan (a derivative of exatecan).[5][6] It is licensed for the treatment of breast cancer or gastric or gastroesophageal adenocarcinoma.[6][7] Trastuzumab binds to and …
Tixagevimab
It’s only fair to share… (Heavy chain) QMQLVQSGPE VKKPGTSVKV SCKASGFTFM SSAVQWVRQA RGQRLEWIGW IVIGSGNTNY AQKFQERVTI TRDMSTSTAY MELSSLRSED TAVYYCAAPY CSSISCNDGF DIWGQGTMVT VSSASTKGPS VFPLAPSSKS TSGGTAALGC LVKDYFPEPV TVSWNSGALT SGVHTFPAVL QSSGLYSLSS VVTVPSSSLG TQTYICNVNH KPSNTKVDKR VEPKSCDKTH TCPPCPAPEF EGGPSVFLFP PKPKDTLYIT REPEVTCVVV DVSHEDPEVK FNWYVDGVEV HNAKTKPREE QYNSTYRVVS VLTVLHQDWL NGKEYKCKVS NKALPASIEK TISKAKGQPR EPQVYTLPPS REEMTKNQVS LTCLVKGFYP SDIAVEWESN GQPENNYKTT PPVLDSDGSF FLYSKLTVDK SRWQQGNVFS CSVMHEALHN HYTQKSLSLS PGK (Light chain) …
DIPYRIDAMOLE
It’s only fair to share… Dipyridamole Molecular FormulaC24H40N8O4 Average mass504.626 Da 2,2′,2”,2”’-{[4,8-Di(piperidin-1-yl)pyrimido[5,4-d]pyrimidine-2,6-diyl]dinitrilo}tetraethanol 200-374-7 [EINECS] 58-32-2 [RN] Ethanol, 2,2′,2”,2”’-[(4,8-di-1-piperidinylpyrimido[5,4-d]pyrimidine-2,6-diyl)dinitrilo]tetrakis- дипиридамол [Russian] [INN] ديبيريدامول [Arabic] [INN] 双嘧达莫 [Chinese] [INN] 0068373 [Beilstein] Dipyridamole CAS Registry Number: 58-32-2 CAS Name: 2,2¢,2¢¢,2¢¢¢-[(4,8-Di-1-piperidinylpyrimido[5,4-d]pyrimidine-2,6-diyl)dinitrilo]tetrakisethanol Additional Names: 2,6-bis(diethanolamino)-4,8-dipiperidinopyrimido-[5,4-d]pyrimidine Manufacturers’ Codes: NSC-515776; RA-8 Trademarks: Anginal (Yamanouchi); Cardoxin (RAFA); Cleridium (Marcofina); Coridil (Delalande); Coronarine (NEGMA); Curantyl (Berlin-Chemie); Dipyridan (Hokuriku); Gulliostin (Taiyo); Natyl (Interdelta); Peridamol (Boehringer, Ing.); Persantine (Boehringer, Ing.); …
Daridorexant
It’s only fair to share… Daridorexant Molecular FormulaC23H23ClN6O2 Average mass450.921 Da [(2S)-2-(5-Chloro-4-methyl-1H-benzimidazol-2-yl)-2-methyl-1-pyrrolidinyl][5-methoxy-2-(2H-1,2,3-triazol-2-yl)phenyl]methanone 1505484-82-1 [RN] Methanone, [(2S)-2-(5-chloro-4-methyl-1H-benzimidazol-2-yl)-2-methyl-1-pyrrolidinyl][5-methoxy-2-(2H-1,2,3-triazol-2-yl)phenyl]- ACT-541468, , Nemorexant FDA APPROVED 2022, 1/7/2022, To treat insomnia, Quviviq Daridorexant HCl CAS#: 1792993-84-0 (HCl) Chemical Formula: C23H24Cl2N6O2 Molecular Weight: 487.39 Elemental Analysis: C, 56.68; H, 4.96; Cl, 14.55; N, 17.24; O, 6.57 Methanone, ((2S)-2-(6-chloro-7-methyl-1H-benzimidazol-2-yl)-2-methyl-1-pyrrolidinyl)(5-methoxy-2-(2H-1,2,3-triazol-2-yl)phenyl)-, hydrochloride (1:1) Daridorexant HCl; Daridorexant hydrochloride; …
TAUROLIDINE
It’s only fair to share… TAUROLIDINE Molecular FormulaC7H16N4O4S2 Average mass284.356 Da 19388-87-5 [RN] 243-016-5 [EINECS] 2H-1,2,4-Thiadiazine, 4,4′-methylenebis[tetrahydro-, 1,1,1′,1′-tetraoxide 4,4′-methanediylbis(1,2,4-thiadiazinane) 1,1,1′,1′-tetraoxide UNII-8OBZ1M4V3V тауролидин توروليدين 牛磺利定 NMR https://www.apexbt.com/downloader/document/C4559/NMR-2.pdf MS https://www.apexbt.com/downloader/document/C4559/MS-2.pdf Taurolidine CAS Registry Number: 19388-87-5 CAS Name: 4,4¢-Methylenebis(tetrahydro-1,2,4-thiadiazine) 1,1,1¢,1¢-tetraoxide Additional Names: 4,4¢-methylenebis(perhydro-1,2,4-thiadiazine 1,1-dioxide); bis(1,1-dioxoperhydro-1,2,4-thiadiazin-4-yl)methane Trademarks: Drainasept (Geistlich); Taurolin (HMR); Tauroflex (Geistlich) Molecular Formula: C7H16N4O4S2, Molecular Weight: 284.36 Percent Composition: C 29.57%, H 5.67%, N 19.70%, O 22.51%, S 22.55% …