It’s only fair to share… News Release FDA approves Eucrisa for eczema The U.S. Food and Drug Administration today approved Eucrisa (crisaborole) ointment to treat mild to moderate eczema (atopic dermatitis) in patients two years of age and older. Read more. For Immediate Release December 14, 2016 Release The U.S. Food and Drug Administration today …
Glenmark Launches First and Only Generic Version of Zetia® (Ezetimibe) in the United States
It’s only fair to share… Illustration Image Courtesy…..link “We have launched ezetimibe, the first and only generic version of Zetia (Merck) in the United States for the treatment of high cholesterol,”……….http://health.economictimes.indiatimes.com/news/pharma/glenmark-launches-generic-version-of-zetia-in-us-market/55951453 see……..http://us-glenmarkpharma.com/wp-content/uploads/Glenmark-launches-first-and-only-generic-version-of-Zetia%C2%AE-in-the-United-States.pdf SEE…..http://www.zeebiz.com/companies/news-glenmark-launches-generic-version-of-cholesterol-drug-zetia-in-us-market-9092 Glenmark Launches First and Only Generic Version of Zetia® in the United States Mumbai, India; December 12, 2016: Glenmark Pharmaceuticals Inc., USA today …
CPP 115
It’s only fair to share… (+)-(1S,4S)-4-Amino-3-(difluoromethylene)-1-cyclopentanecarboxylic acid 640897-20-7 CAS PHASE 1 NORTHWESTERN UNIVERSITY .INNOVATORS Sponsor: Catalyst Pharmaceuticals, Inc. CPP-115 free base; UNII-5TD9324Z2U; CHEMBL146927; 640897-20-7; (1S,3S)-3-Amino-4-difluoromethylenyl-1-cyclopentanoic acid; (+)-(1S,4S)-4-Amino-3-(difluoromethylene)-1-cyclopentanecarboxylic acid Molecular Formula: C7H9F2NO2 Molecular Weight: 177.151 g/mol Originator Northwestern University Developer Catalyst Pharmaceutical Partners Class Aminobutyric acids; Antiepileptic drugs; Small molecules Mechanism of Action 4-aminobutyrate transaminase inhibitors Orphan Drug Status Yes – …
PIMODIVIR, VX 787
It’s only fair to share… PIMODIVIR VX-787, JNJ-63623872, JNJ-872, VRT-0928787, VX-787, VX 787, VX787, JNJ-872, JNJ 872, JNJ872, VRT-0928787, VRT 0928787, VRT0928787, pimodivir (2S,3S)-3-{[5-fluoro-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl]amino}bicyclo[2.2.2]octane-2-carboxylic acid (2S,3S)-3-((2-(5-fluoro-1H-pyrrolo[2,3-b]pyridm-3-yl)-5- fluoropyrimidin-4-yl)amino)bicyclo[2.2.2]octane-2-carboxylic acid (2S,3S)-3-((5-Fluoro-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl)amino)bicyclo[2.2.2]octane-2-carboxylic Acid MF C20H19F2N5O2, MW 399.4018 CAS 1629869-44-8 PHASE 2 Originator Vertex Pharmaceuticals Developer Janssen Pharmaceuticals Mechanism Of Action Viral polymerase inhibitor, Viral protein inhibitor Who Atc Codes …
CEP 33779
It’s only fair to share… CEP-33779, CEP33779 CAS 1257704-57-6 Chemical Formula: C24H26N6O2S Molecular Weight: 462.57 Elemental Analysis: C, 62.32; H, 5.67; N, 18.17; O, 6.92; S, 6.93 N-(3-(4-methylpiperazin-1-yl)phenyl)-8-(4-(methylsulfonyl)phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine PRECLINICAL Treatment of Rheumatoid Arthritis, Agents for Colorectal Cancer Therapy Systemic Lupus Erythematosus, Jak2 Inhibitors Matthew A. Curry, Bruce D. Dorsey, Benjamin J. Dugan, Diane E. Gingrich, Eugen F. Mesaros, Karen L. …
Editorial…..Great leaders inspire their teams to go above and beyond.
It’s only fair to share… Great leaders inspire their teams to go above and beyond. They listen to them, recognise their needs and value the contribution of each team member. It all starts with great relationships – when you collaborate and trust in their abilities engagement and motivation will increase. By admitting mistakes, and …
ADRAFINIL
It’s only fair to share… ADRAFINIL 2-((diphenylmethyl)sulfinyl)-acetohydroxamicaci;2-((diphenylmethyl)sulfinyl)-n-hydroxy-acetamid;2-((diphenylmethyl)sulfinyl)-n-hydroxyacetamide;2-(benzhydrylsulfinyl)acetohydroxamicacid;ADRAFINIL;2-[(DIPHENYLMETHYL)SULFINYL]ACETOHYDROXAMIC ACID;CRL 40028;OLMIFON CAS 63547-13-7 MF:C15H15NO3S MW:289.35 EINECS:264-303-1 WATCH THIS POST AS DETAILS LIKE SYNTHESIS ARE UPDATED…………. Adrafinil is touted mainly for its stimulant properties and ability to provide alertness and wakefulness. Stay up late/stay awake during normal sleeping hours: Adrafinil may be helpful for night workers who need a …
ZINPLAVA (BEZLOTOXUMAB), Approved FDA
It’s only fair to share… BEZLOTOXUMAB Biologic License Application (BLA): 761046 Company: MERCK SHARP DOHME Drug Name(s): • ZINPLAVA (BEZLOTOXUMAB) http://www.accessdata.fda.gov/drugsatfda_docs/label/2016/761046s000lbl.pdf http://www.accessdata.fda.gov/drugsatfda_docs/appletter/2016/761046Orig1s000ltr.pdf Drug Name Active Ingredient Approval Date FDA-approved use on approval date Zinplava bezlotoxumab 10/21/2016 To reduce the recurrence of Clostridium difficile infection in patients aged 18 years or older Drug Trials Snapshot From Wikipedia, …
NEW PATENT, WO2016178162, TENOFOVIR, CBZ INVESTMENTS LTD.
It’s only fair to share… NEW PATENT WO2016178162, SYNTHESIS OF INTERMEDIATES USED IN THE MANUFACTURE OF ANTI-HIV AGENTS CBZ INVESTMENTS LTD. [–/GB]; 122, Feering Hill, Feering, Colchester, Essex CO5 9PY (GB) PRADHAN, Braja Sundar; (IN). AMARNATH, Kommireddy; (IN). VEMPALA, Naresh; (IN). RAHMAN, Md. Ataur; (IN) PRADHAN, Braja Sundar Process for preparing 9-[2-(hydroxyl)propyl]adenine and 9-[2-phosphonomethoxypropyl]adenine, …
Sacubitril
It’s only fair to share… Sacubitril, AHU 377 NEPRILYSIN INHIBITOR FOR HEART FAILURE CAS 149709-62-6 CAS SODIUM SALT 149690-05-1 (2R,4S)-5-(biphenyl-4-yl)-4-((3-carboxypropionyl)amino)-2-methylpentanoic acid ethyl ester 5-(Biphenyl-4-yl)-4(S)-(3-carboxypropionamido)-2(R)-methylbutyric acid ethyl ester N-(3-carboxy-1-oxopropyl)-(4S)-(p-phenylphenylmethyl)-4-amino-2R-methyl butanoic acid ethyl ester [1,1′-Biphenyl]-4-pentanoic acid, γ-[(3-carboxy-1-oxopropyl)amino]-α-methyl-, α-ethyl ester, (αR,γS)- [1,1′-Biphenyl]-4-pentanoic acid, γ-[(3-carboxy-1-oxopropyl)amino]-α-methyl-, ethyl ester, [S-(R*,S*)]- (2R,4S)-4-[(3-Carboxy-1-oxopropyl)amino]-4-[(p-phenylphenyl)methyl]-2-methylbutanoic acid ethyl ester (2R,4S)-5-(Biphenyl-4-yl)-4-[(3-carboxypropionyl)amino]-2-methylpentanoic acid ethyl ester Formula C24H29NO5 MW 411.49 …