It’s only fair to share… Balsalazide 80573-04-2; Colazal; Balsalazide Disodium; AC1NSFNR; P80AL8J7ZP; Molecular Formula: C17H15N3O6 Molecular Weight: 357.322 g/mol (3E)-3-[[4-(2-carboxyethylcarbamoyl)phenyl]hydrazinylidene]-6-oxocyclohexa-1,4-diene-1-carboxylic acid DISODIUMDIHYDRATE CAS Number 150399-21-6 Weight Average: 437.316 Monoisotopic: 437.08110308 Chemical Formula C17H17N3Na2O8 Balsalazide is an anti-inflammatory drug used in the treatment of inflammatory bowel disease. It is sold under the brand names Giazo, …
CENTANAFADINE
It’s only fair to share… Centanafadine; UNII-D2A6T4UH9C; EB-1020 free base; D2A6T4UH9C; 924012-43-1 CTN SR; EB-1020; EB-1020 SR WO 2007016155 Molecular Formula: C15H15N Molecular Weight: 209.292 g/mol Phase II Attention-deficit hyperactivity disorder No development reported Major depressive disorder; Neuropathic pain Most Recent Events 20 Dec 2016 Neurovance plans a phase III trial for Attention-deficit hyperactivity disorder 27 Jul 2016 Efficacy data from …
FDA approves first drug Spinraza (nusinersen), for spinal muscular atrophy
It’s only fair to share… FDA approves first drug for spinal muscular atrophy New therapy addresses unmet medical need for rare disease The U.S. Food and Drug Administration today approved Spinraza (nusinersen), the first drug approved to treat children and adults with spinal muscular atrophy (SMA), a rare and often fatal genetic disease affecting muscle …
Niraparib; MK 4827
It’s only fair to share… MK-4827,(S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxaMide Niraparib; MK 4827; MK4827 UNII:HMC2H89N35 Antineoplastic, Poly(ADP-ribose) Polymerase Inhibitors 1038915-60-4 CAS, free form 1038915-64-8 CAS HYDROCHLORIDE 1613220-15-7 cas TOSYLATE MONOHYDRATE 1038915-73-9 TOSYLATE MK-4827(Niraparib) tosylate is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM; with great activity in cancer cells with mutant BRCA-1 and BRCA-2; >330-fold selective against …
FDA grants accelerated approval to new treatment for advanced ovarian cancer , Rubraca(rucaparib)
It’s only fair to share… The U.S. Food and Drug Administration today granted accelerated approval to Rubraca (rucaparib) to treat women with a certain type of ovarian cancer. Rubraca is approved for women with advanced ovarian cancer who have been treated with two or more chemotherapies and whose tumors have a specific gene mutation (deleterious …
DNDI-VL-2098
It’s only fair to share… DNDI-VL-2098 CAS 681492-17-1 (R)-2-Methyl-6-nitro-2-(4-trifluoromethoxyphenoxymethyl)-2,3-dihydroimidazo[2,1-b]oxazole Watch this post, will be updated……….. MF C14 H12 F3 N3 O5, MW 359.26 Imidazo[2,1-b]oxazole, 2,3-dihydro-2-methyl-6-nitro-2-[[4-(trifluoromethoxy)phenoxy]methyl]-, (2R)- Hidetsugu Tsubouchi, Hirofumi Sasaki, Hideaki Kuroda, Motohiro Itotani, Takeshi Hasegawa, Yoshikazu Haraguchi, Takeshi Kuroda, Takayuki Matsuzaki, Kuninori Tai, Makoto Komatsu, Makoto Matsumoto, Hiroyuki Hashizume, Tatsuo Tomishige, Yuji Seike, Masanori Kawasaki, …
Citarinostat
It’s only fair to share… Citarinostat Treatment of Hematological Malignancies, Molecular Formula, C24-H26-Cl-N5-O3, Molecular Weight, 467.9544, RN: 1316215-12-9 UNII: 441P620G3P 2-[(2-Chlorophenyl)phenylamino]-N-[7-(hydroxyamino)-7-oxoheptyl]-5-pyrimidinecarboxamide 2-((2-Chlorophenyl)phenylamino)-N-(7-(hydroxyamino)-7-oxoheptyl)-5-pyrimidinecarboxamide 5-Pyrimidinecarboxamide, 2-((2-chlorophenyl)phenylamino)-N-(7-(hydroxyamino)-7-oxoheptyl)- ACY-241; HDAC-IN-2 Histone deacetylase-6 inhibitor Acute myelogenous leukemia; Cancer; Mantle cell lymphoma; Multiple myeloma Mechanism of ActionHDAC6 protein inhibitors Highest Development Phases Phase IIMultiple myeloma Phase IMalignant melanoma; Non-small cell lung cancer; Solid …
FDA approves Eucrisa (crisaborole) for eczema
It’s only fair to share… News Release FDA approves Eucrisa for eczema The U.S. Food and Drug Administration today approved Eucrisa (crisaborole) ointment to treat mild to moderate eczema (atopic dermatitis) in patients two years of age and older. Read more. For Immediate Release December 14, 2016 Release The U.S. Food and Drug Administration today …
Glenmark Launches First and Only Generic Version of Zetia® (Ezetimibe) in the United States
It’s only fair to share… Illustration Image Courtesy…..link “We have launched ezetimibe, the first and only generic version of Zetia (Merck) in the United States for the treatment of high cholesterol,”……….http://health.economictimes.indiatimes.com/news/pharma/glenmark-launches-generic-version-of-zetia-in-us-market/55951453 see……..http://us-glenmarkpharma.com/wp-content/uploads/Glenmark-launches-first-and-only-generic-version-of-Zetia%C2%AE-in-the-United-States.pdf SEE…..http://www.zeebiz.com/companies/news-glenmark-launches-generic-version-of-cholesterol-drug-zetia-in-us-market-9092 Glenmark Launches First and Only Generic Version of Zetia® in the United States Mumbai, India; December 12, 2016: Glenmark Pharmaceuticals Inc., USA today …
CPP 115
It’s only fair to share… (+)-(1S,4S)-4-Amino-3-(difluoromethylene)-1-cyclopentanecarboxylic acid 640897-20-7 CAS PHASE 1 NORTHWESTERN UNIVERSITY .INNOVATORS Sponsor: Catalyst Pharmaceuticals, Inc. CPP-115 free base; UNII-5TD9324Z2U; CHEMBL146927; 640897-20-7; (1S,3S)-3-Amino-4-difluoromethylenyl-1-cyclopentanoic acid; (+)-(1S,4S)-4-Amino-3-(difluoromethylene)-1-cyclopentanecarboxylic acid Molecular Formula: C7H9F2NO2 Molecular Weight: 177.151 g/mol Originator Northwestern University Developer Catalyst Pharmaceutical Partners Class Aminobutyric acids; Antiepileptic drugs; Small molecules Mechanism of Action 4-aminobutyrate transaminase inhibitors Orphan Drug Status Yes – …