It’s only fair to share… FOTAGLIPTIN CAS 1312954-58-7 342.37, C17 H19 F N6 O Benzonitrile, 2-[[3-[(3R)-3-amino-1-piperidinyl]-6-methyl-5-oxo-1,2,4-triazin-4(5H)-yl]methyl]-4-fluoro- (R)-2-((3-(3-amino-piperidin-1-yl)-6-methyl-5-oxo-1,2,4-piperazine-4(5H)-yl)methyl)-4-fluorobenzonitrile, BENZOATE 1403496-40-1 (R) 2- Methyl-5-oxo-1,2,4-triazin-4 (5H) -yl) methyl) -4-fluorobenzonitrile (3- benzoate (compound benzoate A), of the formula: the C . 17 the H 19 the FN . 6 O · the C . 7 the H . 6 O 2 …
Brigatinib, Бригатиниб, بريغاتينيب , 布格替尼 ,
It’s only fair to share… Brigatinib, AP26113 Molecular Formula: C29H39ClN7O2P Molecular Weight: 584.102 g/mol CAS 1197953-54-0 2,4-Pyrimidinediamine, 5-chloro-N4-[2-(dimethylphosphinyl)phenyl]-N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]- Бригатиниб[Russian][INN] بريغاتينيب[Arabic][INN] 布格替尼[Chinese][INN] 5-chloro-N4-[2-(dimethylphosphinyl)phenyl]-N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-2,4-pyrimidinediamine AP-26113 MFCD29472221 UNII:HYW8DB273J In 2016, orphan drug designation was assigned to the compound in the U.S. for the treatment of ALK, ROS1 or EGFR-positive non-small cell lung cancer (NSCLC). WO 2009143389 PDT PAT Inventors Yihan …
HS-10168
It’s only fair to share… HS-10168 CAS 1394346-15-6 471.26, C21 H19 Cl2 F2 N2 O2 P (R)-(4-(6-Amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-3-fluorophenyl)dimethylphosphine Oxide (HS-10168) 2-Pyridinamine, 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[4-(dimethylphosphinyl)-2-fluorophenyl]- HS-10168 is a potent and selective mesenchymal epithelial transition factor/anaplastic lymphoma kinase (c-Met/ALK) inhibitor that has advanced into Phase I clinical trials.(1, 2) Inventors Baihua Hu, Kan He, Minsheng Zhang Applicant Jiangsu Hansoh Pharmaceutical Co., …
Amtolmetin guacil, амтолметин гуацил , أمتولمتين غواسيل , 呱氨托美丁
It’s only fair to share… Amtolmetin guacil, ST-679, MED-15, Eufans CAS 87344-06-7 UNII: 323A00CRO9, Molecular Formula, C24-H24-N2-O5, Molecular Weight, 420.463, 2-Methoxyphenyl 1-methyl-5-p-methylbenzoylpyrrole-2-acetoamidoacetate Glycine, N-((5-benzoyl-1-methyl-1H-pyrrol-2-yl)acetyl)-, 2-methoxyphenyl ester Trade names: Amtoril®, Artricol®, Artromed® US 4578481, US 6288241, MEDOSAN RICERCA S.R.L. [IT/IT]; Via Cancelliera, 12 I-00040 Cecchina RM (IT) (For All Designated States Except US). SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE …
SL65.0102-10
It’s only fair to share… CAS 186348-69-6 1,4-Benzodioxin-5-carboxamide, 8-amino-7-chloro-N-(1,4-diazabicyclo[2.2.2]oct-2-ylmethyl)-2,3-dihydro-, (-)- MW, 352.82, C16 H21 Cl N4 O3 US5663173 (A) – N-[(1,4-diazabicyclo[2.2.2] oct-2-yl)methyl] benzamide derivatives, their preparations and their application in therapeutics SL65.0102-10 (-)-1,4-benzodioxin-5-carboxamide-8-amino-7-chloro-N-(1,4-diazabicyclo[2.2.2]oct-2- ylmethyl)-2,3-dihydro-, hydrochloride 1,4-Benzodioxin-5-carboxamide, 8-amino-7-chloro-N-(1,4-diazabicyclo[2.2.2]oct-2-ylmethyl)-2,3-dihydro-, hydrochloride (1:2), (-)- 1,4-Benzodioxin-5-carboxamide, 8-amino-7-chloro-N-(1,4-diazabicyclo[2.2.2]oct-2-ylmethyl)-2,3-dihydro-, dihydrochloride, (-)- Dihydrochloride (-) – 8-Amino-7-chloro- N – [(1,4-diazabicyclo [2.2.2] oct-2-yl) methyl] -2,3-dihydro-1,4-benzodioxin-5 -carboxamide. …
Production of High-Quality Diesel from Biomass Waste Products
It’s only fair to share… The use of biodiesel has been promoted for the past decade as a substitute for fossil-based diesel fuel. However, it has become evident that its production competes with food production by engrossing cropland. To overcome this Corma has developed a process that uses 2-methylfuran which currently is isolated (280 × …
Acid Chloride Negishi Couplings
It’s only fair to share… With the plethora of new and efficient C–C bond-forming reactions available to the organic chemists growing on a monthly basis, one area that suffers is the substrate scope for previously reported examples. In this case Kim and Reike ( Tetrahedron Lett. 2011, 52, 1523−1526) reinvestigate work originally reported by Rovis. …
Cimaglermin alfa , GGF2
It’s only fair to share… Cimaglermin alfa , GGF2 RN: 1350717-96-2, UNII: B2A4EZ9I83 CGF-2; GGF-2 – Acorda; Glial growth factor 2 – Acorda; Neuregulin 1 protein; Neuregulin 1β3; NRG1 protein; Recombinant human glial growth factor-2 (rhGGF 2) – Acorda Therapeutics; rhGGF2 – Acorda Treatment of Congestive Heart Failure, rhGGF 2 Molecular Formula, C1747-H2770-N502-O535-S17 (unglycosylated), Molecular Weight, 39923.2958 Glial growth …
WO 2016200930, New patent, Citarinostat, Acetylon Pharmaceuticals Inc
It’s only fair to share… WO 2016200930, New patent, Citarinostat, Acetylon Pharmaceuticals Inc citarinostat Acetylon Pharmaceuticals Inc (WO2016200930) METHODS OF MAKING PROTEIN DEACETYLASE INHIBITORS (I) Compound (I) is disclosed in U.S. Patent No. 8,148,526 as an HDAC inhibitor. Example 2 of U.S. Patent Application Publication No. 2015/0099744 discloses a synthesis of compound (I). As detailed …
Calcifediol, カルシフェジオール
It’s only fair to share… Calcifediol カルシフェジオール Ro 8-8892 U 32070E (3b,5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-3,25-diol (3S,5Z,7E,20R)-9,10-Secocholesta-5,7,10-trien-3,25-diol [German] [ACD/IUPAC Name] (3S,5Z,7E,20R)-9,10-Secocholesta-5,7,10-triene-3,25-diol [ACD/IUPAC Name] (3S,5Z,7E,20R)-9,10-Sécocholesta-5,7,10-triène-3,25-diol [French] [ACD/IUPAC Name] 19356-17-3 [RN] 1H-indene-1-pentanol, octahydro-4-[(2Z)-2-[(5S)-5-hydroxy-2-methylenecyclohexylidene]ethylidene]-a,a,e,7a-tetramethyl-, (eR,1R,3aS,4E,7aR)- 25(OH)D3 25-(OH)Vitamin D3 25-hydroxy Vitamin D3 25-HYDROXYCHOLECALCIFEROL-D6 25-hydroxycholecalciferolmonohydrate 25-hydroxyvitamin D 3-{2-[1-(5-Hydroxy-1,5-dimethyl-hexyl)-7a-methyl-octahydro-inden-4-ylidene]-ethylidene}-4-methylene-cyclohexanol 4-[(2Z)-2-[(5S)-5-hydroxy-2-methylenecyclohexylidene]ethylidene]octahydro-?,?,?,7a-tetramethyl-(?R,1R,3aS,4E,7aR)-1H-indene-1-pentanol Molecular form.: C₂₇H₄₄O₂ Appearance: White to Off-White Solid Melting Point: 75-93ºC Mol. Weight: 400.64 Calcifediol …