It’s only fair to share… SULCONAZOLE сульконазол , سولكونازول , 硫康唑 Molecular FormulaC18H15Cl3N2S Average mass397.749 Da 1H-Imidazole, 1-[2-[[(4-chlorophenyl)methyl]thio]-2-(2,4-dichlorophenyl)ethyl]- [ACD/Index Name] 4332 5D9HAA5Q5S 61318-90-9 [RN] (±)-1-[2,4-Dichloro-b-[(p-chlorobenzyl)thio]phenethyl]imidazole 1-[2-[[(4-Chlorophenyl)methyl]thio]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole : Sulconazole CAS Registry Number: 61318-90-9 CAS Name: 1-[2-[[(4-Chlorophenyl)methyl]thio]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole Additional Names: (±)-1-[2,4-dichloro-b-[(p-chlorobenzyl)thio]phenethyl]imidazole Molecular Formula: C18H15Cl3N2S Molecular Weight: 397.75 Percent Composition: C 54.35%, H 3.80%, Cl 26.74%, N 7.04%, S 8.06% Literature References: Prepn: K. A. M. Walker, DE2541833; idem,US4055652 (1976, 1977 both to …
TNO 155
It’s only fair to share… TNO 155 2-Oxa-8-azaspiro[4.5]decan-4-amine, 8-[6-amino-5-[(2-amino-3-chloro-4-pyridinyl)thio]-2-pyrazinyl]-3-methyl-, (3S,4S)- (3S,4S)-8-[6-Amino-5-[(2-amino-3-chloro-4-pyridinyl)thio]-2-pyrazinyl]-3-methyl-2-oxa-8-azaspiro[4.5]decan-4-amine (3S,4S)-8-(6-amino-5-((2-amino-3-chloropyridin-4-yl)thio)pyrazin-2-yl)-3-methyl-2-oxa-8-azaspiro[4.5]decan-4-amine Molecular Weight 421.95 Formula C₁₈H₂₄ClN₇OS CAS No. 1801765-04-7 PTPN11 inhibitor TNO155 SHP2 inhibitor TNO155 TNO-155 TNO155 UNII-FPJWORQEGI TNO155 is a potent selective and orally active allosteric inhibitor of wild-type SHP2 (IC50=0.011 µM). TNO155 has the potential for the study of RTK-dependent malignancies, especially …
CILENGITIDE
It’s only fair to share… IUPAC Condensed cyclo[Arg-Gly-Asp-D-Phe-N(Me)Val] HELM PEPTIDE1{R.G.D.[dF].[meV]}$PEPTIDE1,PEPTIDE1,5:R2-1:R1$$$ IUPAC cyclo[L-arginyl-glycyl-L-alpha-aspartyl-D-phenylalanyl-N-methyl-L-valyl] CILENGITIDE Molecular FormulaC27H40N8O7 Average mass588.656 Da 2-[(2S,5R,8S,11S)-5-benzyl-11-[3-(diaminomethylideneamino)propyl]-7-methyl-3,6,9,12,15-pentaoxo-8-propan-2-yl-1,4,7,10,13-pentazacyclopentadec-2-yl]acetic acid 188968-51-6 [RN] 4EDF46E4GI 7823 циленгитид سيلانجيتيد 西仑吉肽 EMD 121974, EMD-121974, UNII-4EDF46E4GI 2-[(2S,5R,8S,11S)-5-benzyl-11-[3-(diaminomethylideneamino)propyl]-7-methyl-3,6,9,12,15-pentaoxo-8-propan-2-yl-1,4,7,10,13-pentazacyclopentadec-2-yl]acetic acid Cilengitide has been in phase III clinical trials by Merck Serono and NCI for the treatment of glioblastoma multiforme. However, this research has been …
Methotripremazine
It’s only fair to share… Methotripremazine 60-99-1 7104-38-3 (maleate), 1236-99-3 HCl) CL 36467 CL 39743 N05AA02 RP 7044 RP-7044 SK&F 5116 XP-03 XP03 Product Ingredients INGREDIENT UNII CAS INCHI KEY Methotrimeprazine hydrochloride 42BB1Y2586 1236-99-3 ODLGFPIWRAEFAN-PFEQFJNWSA-N Methotrimeprazine maleate 5KN5Y9V01K 7104-38-3 IFLZPECPTYCEBR-VIEYUMQNSA-N Methotrimeprazine CAS Registry Number: 60-99-1 CAS Name: (bR)-2-Methoxy-N,N,b-trimethyl-10H-phenothiazine-10-propanamine Additional Names: (-)-10-(3-dimethylamino-2-methylpropyl)-2-methoxyphenothiazine; levomepromazine; 2-methoxytrimeprazine; levomeprazine Manufacturers’ Codes: RP-7044 Trademarks: Sinogan-Debil; Tisercin (EGYT); Neozine …
Methiomeprazine
It’s only fair to share… Methiomeprazine N,N,2-trimethyl-3-(2-methylsulfanylphenothiazin-10-yl)propan-1-amine CAS 7009-43-0 Molecular Formula, C19-H24-N2-S2, Molecular Weight, 344.5446, 10H-Phenothiazine-10-propanamine, N,N,β-trimethyl-2-(methylthio)-, (±)- Phenothiazine, 10-[3-(dimethylamino)-2-methylpropyl]-2-(methylthio)-, (±)- (8CI) N,N,β-Trimethyl-2-(methylthio)-10H-phenothiazine-10-propanamine (±)-10-(3-Dimethylamino-2-methylpropyl)-2-(methylthio)phenothiazine 10584-RP 2-Methylthio-10-(2-methyl-3-dimethylaminopropyl)phenothiazine Methiomeprazine SKF 6270 (+-)-10-(3-Dimethylamino-2-methylpropyl)-2-(methylthio)phenothiazine Phenothiazine, 10-(3-(dimethylamino)-2-methylpropyl)-2-(methylthio)-, (+-)- 10584 RP EINECS 230-285-9 Methiomeprazinum Methiomeprazinum [INN-Latin] Metiomeprazina Metiomeprazina [INN-Spanish] RP 10584 SKF 6270 UNII-X2R9QTF0OL Methiomeprazine hydrochloride 14056-64-5 Methiomeprazine maleate 101037-46-1 join me on Linkedin …
Dichlorquinazine
It’s only fair to share… CORRECT STR OF Dichlorquinazine 7-chloro-N-[1-[4-[2-[(7-chloroquinolin-4-yl)amino]propyl]piperazin-1-yl]propan-2-yl]quinolin-4-amine;methanesulfonic acid 1,4-Piperazinediethanamine, N,N’-bis(7-chloro-4-quinolinyl)-α,α’-dimethyl- (9CI) Quinoline, 4,4-[1,4-piperazinediylbis[(1-methylethylene)imino]]bis[7-chloro- (7CI) Quinoline, 4,4′-[1,4-piperazinediylbis[(1-methylethylene)imino]]bis[7-chloro- (8CI) N1,N4-Bis(7-chloro-4-quinolinyl)-α1,α4-dimethyl-1,4-piperazinediethanamine 1,4-Bis[2-(7-chloro-4-quinolylamino)propyl]piperazine Bis[(chloro-7”-quinolyl-4”)amino-2′-propyl]-1,4-piperazine Dichlorquinazine N,N’-Bis(7-chloro-4-quinolyl)-α,α’-dimethylpiperazine-1,4-diethylamine NSC 129790 RP 12278 WR 3863 WRONG STRUCTURE WRONG STRUCTURE Dichlorquinazine BRN 0867697 Dichlorquinazine EINECS 234-130-6 NSC 129790 RP 12278 UNII-HT3GAD2SCM WR 3863 cas 10547-40-7 C28H32Cl2N6, mw 523.5 7-chloro-N-[2-[4-[2-[(7-chloroquinolin-4-yl)amino]propan-2-yl]piperazin-1-yl]propan-2-yl]quinolin-4-amine …
RP 12146
It’s only fair to share… RP 12146, EX-A7910 cas 2732869-64-4 4-[[5-[(3R)-3-hydroxy-3-methyl-2-oxoindol-1-yl]pyridin-3-yl]methyl]-2H-phthalazin-1-one M.Wt 398.422 Formula C23H18N4O3 RP12146 (RP12146) is a novel, selective, and potent small molecule inhibitor of PARP1/2 with IC50 of 0.6/0.5 nM, with several fold selectivity over other isoforms. SCHEME Ref WO2021220120 Rhizen Pharmaceuticals AG WO2022215034 Rhizen Pharmaceuticals AG; Incozen Therapeutics Pvt. Ltd. RP-12146 …
LERIGLITAZONE
It’s only fair to share… LERIGLITAZONE C19H20N2O4S, MW 372.4 Hydroxypioglitazone, CAS 146062-44-4 MIN 102, Hydroxy Pioglitazone (M-IV) лериглитазон [Russian] [INN] ليريغليتازون [Arabic] [INN] 乐立格列酮 [Chinese] [INN] 5-[[4-[2-[5-(1-hydroxyethyl)pyridin-2-yl]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione Hydroxypioglitazone is a member of the class of thiazolidenediones that is the hydroxy derivative of pioglitazone. It has a role as a human xenobiotic metabolite. It is a member of thiazolidinediones, a member of pyridines and an aromatic ether. …
DOMPERIDONE
It’s only fair to share… DOMPERIDONE Molecular FormulaC22H24ClN5O2 Average mass425.911 Da 1H-Benzimidazol-2-ol, 5-chloro-1-[1-[3-(2-hydroxy-1H-benzimidazol-1-yl)propyl]-4-piperidinyl]- 260-968-7 [EINECS] 2H-Benzimidazol-2-one, 5-chloro-1-[1-[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-4-piperidinyl]-1,3-dihydro- 4-(5-Chloro-2-oxo-1-benzimidazolinyl)-1-[3-(2-oxobenzimidazolinyl)propyl]piperidine 57808-66-9 [RN] домперидон دومبيريدون 多潘立酮 CAS Registry Number: 57808-66-9 CAS Name: 5-Chloro-1-[1-[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one Additional Names: 5-chloro-1-[1-[3-(2-oxo-1-benzimidazolinyl)propyl]-4-piperidyl]-2-benzimidazolinone Manufacturers’ Codes: R-33812 Trademarks: Euciton (Roux-Ocefa); Evoxin (Sterling Winthrop); Gastronorm (Janssen); Mod (Irbi); Motilium (Janssen); Nauzelin (Janssen); Peridon (Italchimici); Peridys (Robapharm) Molecular Formula: C22H24ClN5O2 Molecular Weight: 425.91 Percent Composition: C 62.04%, H …
MEBEVERINE
It’s only fair to share… MEBEVERINE Molecular FormulaC25H35NO5 Average mass429.549 Da 3,4-Dimethoxybenzoic Acid 4-[Ethyl[2-(4-methoxyphenyl)-1-methylethyl]amino]butyl Ester 3625-06-7 [RN] 222-830-4[EINECS] 3,4-Diméthoxybenzoate de 4-{éthyl[1-(4-méthoxyphényl)-2-propanyl]amino}butyle мебеверин ميبيفيرين 美贝维林 EINECS:222-830-4 LD50:24 mg/kg (M, i.v.); 995 mg/kg (M, p.o.) Derivatives hydrochloride Formula:C25H35NO5 • HCl MW:466.02 g/mol CAS-RN:2753-45-9 EINECS:220-400-0 LD50:17.7 mg/kg (R, i.v.); 1540 mg/kg (R, p.o.) Mebeverine CAS Registry Number: 3625-06-7 CAS Name: 3,4-Dimethoxybenzoic acid 4-[ethyl[2-(4-methoxyphenyl)-1-methylethyl]amino]butyl …