It’s only fair to share… Umeclidinium bromide GSK-573719A, ウメクリジニウム臭化物 Molecular FormulaC29H34BrNO2 Average mass508.490 Da 1-[2-(Benzyloxy)ethyl]-4-[hydroxy(diphenyl)methyl]-1-azoniabicyclo[2.2.2]octane bromide 1-Azoniabicyclo[2.2.2]octane, 4-(hydroxydiphenylmethyl)-1-[2-(phenylmethoxy)ethyl]-, bromide (1:1) diphenyl-[1-(2-phenylmethoxyethyl)-1-azoniabicyclo[2.2.2]octan-4-yl]methanol;bromide 7AN603V4JV 869113-09-7 [RN] 9551 GSK573719A; UNII-7AN603V4JV Umeclidinium bromide (trade name Incruse Ellipta) is a long-acting muscarinic antagonist approved for the maintenance treatment of chronic obstructive pulmonary disease (COPD).[1] It is also approved for this indication in combination with vilanterol (as umeclidinium bromide/vilanterol).[2][3] In the 2014, …
Ivosidenib, ивосидениб , إيفوزيدينيب , 艾伏尼布 ,
It’s only fair to share… Ivosidenib AG-120; TIBSOVO FDA approves first targeted treatment Tibsovo (ivosidenib) for patients with relapsed or refractory acute myeloid leukemia who have a certain genetic mutation The U.S. Food and Drug Administration today approved Tibsovo (ivosidenib) tablets for the treatment of adult patients with relapsed or refractory acute myeloid leukemia (AML) …
Vilanterol trifenatate, ビランテロールトリフェニル酢酸塩
It’s only fair to share… Vilanterol trifenatate, ビランテロールトリフェニル酢酸塩 ビランテロールトリフェナテート UNII-40AHO2C6DG; GW642444M; CAS 503070-58-4 free form, 503068-34-6 HY-14300A, CS-1679 444 642444 GSK-642444 GW-642444 GW-642444M 4-[(1R)-2-[6-[2-[(2,6-dichlorophenyl)methoxy]ethoxy]hexylamino]-1-hydroxyethyl]-2-(hydroxymethyl)phenol;2,2,2-triphenylacetic acid 1,3-Benzenedimethanol, α1-[[[6-[2-[(2,6-dichlorophenyl)methoxy]ethoxy]hexyl]amino]methyl]-4-hydroxy-, (α1R)- 4-{(1R)-2-[(6-{2-[(2,6-Dichlorbenzyl)oxy]ethoxy}hexyl)amino]-1-hydroxyethyl}-2-(hydroxymethyl)phenol Molecular Formula: C44H49Cl2NO7 Molecular Weight: 774.776 g/mol 4-[(1R)-2-({6-[(2-{[(2,6-Dichlorophenyl)methyl]oxy}ethyl)oxy]hexyl}-amino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol Acetate Salt J. Med. Chem., 2010, 53 (11), pp 4522–4530 DOI: 10.1021/jm100326d white crystalline solid: mp (DSC) 131.9−134.2 °C, [α]D 20 −14.6 (c 1.034 in MeOH). MS ES …
BMS-978587
It’s only fair to share… BMS-978587 Molecular Formula: C26H35N3O3 CAS 1629125-65-0 Molecular Weight: 437.582 US9675571 PATENT Inventor James Aaron Balog Audris Huang Bin Chen Libing Chen Steven P. Seitz Amy C. Hart Jay A. Markwalder AssigneeBristol-Myers Squibb Co Priority date 2013-03-15 IDO-IN-4; 1629125-65-0; SCHEMBL17456163; AKOS030526622; ZINC521836543; CS-5086 (1R,2S)-2-[4-(Di-isobutylamino)-3-(3-(p-tolyl)ureido)phenyl] Cyclopropanecarboxylic Acid (1R,2S)-2-[4-[bis(2-methylpropyl)amino]-3-[(4-methylphenyl)carbamoylamino]phenyl]cyclopropane-1-carboxylic acid (lR,2S)-2-(4-(diisobutylamino)-3-(3-(p- tolyl)ureido)phenyl)cyclopropanecarboxylic acid BMS-978587 was discovered and developed within Bristol-Myers Squibb …
YINLITINIB
It’s only fair to share… YINLITINIB error EMAIL ME amcrasto@gmail.com (E)-4-[(4aR,7aS)-2,3,4a,5,7,7a-hexahydro-[1,4]dioxino[2,3-c]pyrrol-6-yl]-N-[4-(3-chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]but-2-enamide (E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)-4-((4aR,7aS)-tetrahydro-2H-[1,4]dioxin[2,3-c]pyrrol-6(3H)-yl)but-2-enamide CAS 1637253-79-2 2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-4-[(4aR,7aS)-hexahydro-6H-1,4-dioxino[2,3-c]pyrrol-6-yl]-, (2E)-rel– C25 H25 Cl F N5 O4, 513.95 DNT-04110 ; yinlitinib maleate , Guangdong Hec Pharmaceutical Use for treating proliferative diseases, atherosclerosis and pulmonary fibrosis Phase I CHINA NOTE AND USE YOUR JUDGMENT ON DRUG SUBSTANCE, EMAIL ME amcrasto@gmail.com Molecular Formula: C25H25ClFN5O4 Molecular Weight: …
Carglumic acid, карглумовая кислота , حمض كاروغلوميك , カルグルミ酸 ,
It’s only fair to share… Carglumic acid N-Carbamyl-L-glutamate; Molecular FormulaC6H10N2O5 Average mass190.154 Da N-Carbamylglutamate карглумовая кислота [Russian] [INN] حمض كاروغلوميك [Arabic] [INN] カルグルミ酸; 1188-38-1 [RN] 5L0HB4V1EW 8008 L-Glutamic acid, N-(aminocarbonyl)- L-Glutamic acid, N-(hydroxyiminomethyl)- N-[Hydroxy(imino)methyl]-L-glutamic acid (S)-2-Ureidopentanedioic acid (S)-2-ureidopentanedioic acid; N-Carbamoyl-L-Glutamic Acid; N-Carbamyl-L-glutamate; N-Carbamylglutamate OE 312 / OE-312, UNII5L0HB4V1EW Prepn: H. McIlwain, Biochem. J. 33, 1942 (1939) Carglumic acid is a Carbamoyl Phosphate Synthetase 1 Activator. The mechanism …
2,6-Dihydroxy-4-methylbenzoic Acid
It’s only fair to share… 1H NMR 1H NMR (298.2 K, DMSO-d6, 300 MHz, δ in ppm): C 10.87 (br. s, 3 H, H17,12,11), B 6.21 (d, 2 H, J = 0.57 Hz, H14,13), A 2.17 (s, 3 H, H9). 13C NMR 13C NMR (298.2 K, DMSO-d6, 300 MHz, δ in ppm): 9 21.57(C9), 2 …
Mercaptamine bitartrate, システアミン , меркаптамин , 巯乙胺
It’s only fair to share… Mercaptamine bitartrate 2-aminoethanethiol;2,3-dihydroxybutanedioic acid Molecular Formula: C6H13NO6S Molecular Weight: 227.231 g/mol Cystagon; Cysteamine – Mylan/Orphan Europe; Cysteamine bitartrate Procysbi; CYSTEAMINE BITARTRATE; 27761-19-9; CHEBI:50386; (+/-)-Tartaric Acid INGREDIENT UNII CAS Cysteamine Bitartrate QO84GZ3TST 27761-19-9 Cysteamine Hydrochloride IF1B771SVB 156-57-0 Cysteamine bitartrate is a mercaptoethylamine compound that is endogenously derived from the COENZYME A …
Tecovirimat
It’s only fair to share… Tecovirimat Molecular FormulaC19H15F3N2O3 Average mass376.329 Da 816458-31-8 [RN] 869572-92-9 [RN] UNII-F925RR824R тековиримат [Russian] تيكوفيريمات [Arabic] 替韦立马 [Chinese] Benzamide, N-[(3aR,4R,4aR,5aS,6S,6aS)-3,3a,4,4a,5,5a,6,6a-octahydro-1,3-dioxo-4,6-ethenocycloprop[f]isoindol-2(1H)-yl]-4-(trifluoromethyl)- N-[(1R,2R,6S,7S,8S,10R)-3,5-Dioxo-4-azatetracyclo[5.3.2.02,6.08,10]dodec-11-en-4-yl]-4-(trifluoromethyl)benzamide INGREDIENT UNII CAS INCHI KEY Tecovirimat monohydrate SB96YO2BR8 1162664-19-8 QRHXYGPOQKLBJP-NPIFKJBVSA-N Tecovirimat, sold under the brand name Tpoxx among others,[6] is an antiviral medication with activity against orthopoxviruses such as smallpox and monkeypox.[4][7][8] It is the first antipoxviral drug approved in the United States.[9][10] It is an …
ROXADUSTAT
It’s only fair to share… ROXADUSTAT ASP1517; ASP 1517; ASP-1517; FG-4592; FG 4592; FG4592; Roxadustat. CAS 808118-40-3 Chemical Formula: C19H16N2O5 Exact Mass: 352.10592 Fibrogen, Inc. THERAPEUTIC CLAIM, Treatment of anemia Roxadustat nonproprietary drug name CHEMICAL NAMES (4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carbonyl)glycine 1. Glycine, N-[(4-hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]- 2. N-[(4-hydroxy-1-methyl-7-phenoxyisoquinolin-3-yl)carbonyl]glycine MF C19H16N2O5 MW 352.3 SPONSOR FibroGen CODE FG-4592; ASP1517 CAS 808118-40-3 WHO NUMBER 9717 Roxadustat, …