It’s only fair to share… MITAPIVAT CAS 1260075-17-9 MF C24H26N4O3S MW 450.55 UPDATE…. FDA APPROVE 2/17/2022 To treat hemolytic anemia in pyruvate kinase deficiency, Pyrukynd митапиват [Russian] [INN] ميتابيفات [Arabic] [INN] 米他匹伐 [Chinese] [INN] 10226 1260075-17-9 [RN] 2WTV10SIKH AG-348 8-Quinolinesulfonamide, N-[4-[[4-(cyclopropylmethyl)-1-piperazinyl]carbonyl]phenyl]- N-[4-[[4-(Cyclopropylmethyl)-1-piperazinyl]carbonyl]phenyl]-8-quinolinesulfonamide Originator Agios Pharmaceuticals Class Antianaemics; Piperazines; Quinolines; Small molecules; Sulfonamides Mechanism of Action Pyruvate kinase stimulants Orphan Drug Status Yes – Inborn error metabolic disorders …
ABACAVIR
It’s only fair to share… Abacavir CAS Registry Number: 136470-78-5 CAS Name: (1S,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol Additional Names: (-)-cis-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol Manufacturers’ Codes: 1592U89 Molecular Formula: C14H18N6O Molecular Weight: 286.33 Percent Composition: C 58.73%, H 6.34%, N 29.35%, O 5.59% Literature References: Nucleoside reverse transcriptase inhibitor (NRTI). Prepn: S. M. Daluge, EP 349242 (1990 to Wellcome Found.); idem, US 5034394 (1991 to Burroughs Wellcome). Asymmetric synthesis: M. T. Crimmins, B. W. King, J. Org. Chem. 61,4192 (1996). …
FDA approves new treatment for hospital-acquired and ventilator-associated bacterial pneumonia
It’s only fair to share… The U.S. Food and Drug Administration today approved a new indication for the previously FDA-approved drug, Zerbaxa (ceftolozane and tazobactam) for the treatment of hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia (HABP/VABP) in patients 18 years and older. The FDA initially approved Zerbaxa in 2014 to treat complicated intra-abdominal infections …
Onasemnogene abeparvovec オナセムノジーンアベパルボベック
It’s only fair to share… Onasemnogene abeparvovec オナセムノジーンアベパルボベック DNA (synthetic adeno-associated virus 9 vector scAAV9.CB.hSMN human survivor motor neuron protein-specifying) Zolgensma FDA 2019/5/24 APPROVED CAS: 1922968-73-7 AVXS-101 Spinal muscular atrophy treatment Treatment of Spinal Muscular Atrophy (SMA) Type 1 Gene therapy product Onasemnogene abeparvovec, sold under the trade name Zolgensma, is a gene therapy medication used to treat spinal muscular atrophy (SMA). …
FDA approves first PI3K inhibitor Piqray (alpelisib) for breast cancer
It’s only fair to share… FDA approves first PI3K inhibitor for breast cancer syn https://newdrugapprovals.org/2018/06/25/alpelisib-byl-719/ Today, the U.S. Food and Drug Administration approved Piqray (alpelisib) tablets, to be used in combination with the FDA-approved endocrine therapy fulvestrant, to treat postmenopausal women, and men, with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative, PIK3CA-mutated, advanced …
CT-1812
It’s only fair to share… CT-1812 Elayta Condition(s): Alzheimer’s Disease U.S. FDA Status: Alzheimer’s Disease (Phase 2) Company: Cognition Therapeutics Inc. CAS: 1802632-22-9 Chemical Formula: C24H33NO4S Molecular Weight: 431.591 2-(tert-butoxy)-4-(3-methyl-3-(5-(methylsulfonyl)isoindolin-2-yl)butyl)phenol Phenol, 4-[3-[1,3-dihydro-5-(methylsulfonyl)-2H-isoindol-2-yl]-3-methylbutyl]-2-(1,1-dimethylethoxy)- Originator Cognition Therapeutics Class Antidementias; Neuroprotectants; Nootropics; Small molecules Mechanism of Action Sigma-2 receptor antagonists Phase II Alzheimer’s disease Phase I Cognition disorders 21 Feb 2019 Cognition Therapeutics receives patent for …
Dipivefrine, дипивефрин , ديبيفيفرين , 地匹福林 , ジピベフリン
It’s only fair to share… Dipivefrine Molecular FormulaC19H29NO5 Average mass351.437 Da 4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diyl bis(2,2-dimethylpropanoate) 52365-63-6 [RN] (±)-3,4-Dihydroxy-a-[(methylamino)methyl]benzyl Alcohol 3,4-Dipivalate 1-(3′,4′-Dipivaloyloxyphenyl)-2-methylamino-1-ethanol 2,2-Dimethylpropanoic acid 4-[1-hydroxy-2-(methylamino)ethyl]-1,2-phenylene ester дипивефрин [Russian] [INN] ديبيفيفرين [Arabic] [INN] 地匹福林 [Chinese] [INN] ジピベフリン 4-[1-hydroxy-2-(methylamino)ethyl]-o-phenylene divavalate D Epifrin [Trade name] Diopine [Trade name] MFCD00673243 [MDL number] Pivalephrine [Trade name] Pro-Epinephrine Propine [Trade name] Thilodrin [Trade name] ATC:S01EA02 Use:antiglaucoma Dipivefrine hydrochloride CAS 64019-93-8 Formula:C19H29NO5 • HCl MW:387.90 g/mol Dipivefrine (INN) or dipivefrin (USAN), trade name Propine among …
Etosalamide, этосаламид , إيتوسالاميد , 依托柳胺 ,
It’s only fair to share… Etosalamide ethosalamide Cas 15302-15-5 Chemical Formula: C11H15NO3 Molecular Weight: 209.245 o-(2-Ethoxyethoxy)benzamide 1585 1PU994YJUH этосаламид [Russian] [INN] إيتوسالاميد [Arabic] [INN] 依托柳胺 [Chinese] [INN] 2-(2-ethoxyethoxy)benzamide UNII-1PU994YJUH 1PU994YJUH HY-B1015 ZINC3623372 AKOS030526102 CCG-213900 CS-4528 AB01563362_01 SR-01000944263 SR-01000944263-1 Etosalamide, also known as Ethosalamide, is an antipyretic and analgesics agent SYN OR CAS:592-55-2, 2-Bromoethyl ethyl ether Cas, 611-20-1, 2-Hydroxybenzonitrile PATENT DE 1013643 PATENT GB 774635 PATENT US2822391 78 …
GUEST POST, POOJA KUMAR, CURRENT SCENARIO OF PATENTS IN INDIA
It’s only fair to share… CURRENT SCENARIO OF PATENTS IN INDIA By Ms. Pooja Kumar (Registered Patent agent/Director of Innove Intellects) Email id: pooja@innoveintellects.com Patent is a monopoly, exclusive rights given to an individual or a company or an organization to make, sell, use and import an invention for a limited period of years. In …
FDA approves first treatment Ruzurgi (amifampridine) for children with Lambert-Eaton myasthenic syndrome, a rare autoimmune disorder
It’s only fair to share… FDA approves first treatment Ruzurgi (amifampridine) for children with Lambert-Eaton myasthenic syndrome, a rare autoimmune disorder The U.S. Food and Drug Administration today approved Ruzurgi (amifampridine) tablets for the treatment of Lambert-Eaton myasthenic syndrome (LEMS) in patients 6 to less than 17 years of age. This is the first FDA …