It’s only fair to share… Nefopam Molecular Formula C17H19NO Average mass 253.339 Da Cas 13669-70-0 [RN] 1H-2,5-Benzoxazocine, 3,4,5,6-tetrahydro-5-methyl-1-phenyl- 237-148-2 [EINECS] 3,4,5,6-Tetrahydro-5-methyl-1-phenyl-1H-2,5-benzoxazocine SCX-001 Derivative Type: Hydrochloride CAS Registry Number: 23327-57-3 Additional Names: Fenazoxine SCX-001, R-738 Non-Opioid Analgesics Wound-Healing Agents Biocodex, 1983 pain Нефопама Гидрохлорид 塩酸ネホパム Nefopam, sold under the brand names Acupan among others, is a painkilling medication. It is primarily used to treat moderate, acuteor chronic pain. [3] …
Category «Uncategorized»
Secnidazole, секнидазол , سيكنيدازول , 塞克硝唑 ,
It’s only fair to share… Secnidazole Molecular FormulaC7H11N3O3 Average mass185.180 Da 1-(2-Methyl-5-nitroimidazol-1-yl)-2-propanol 1H-Imidazole-1-ethanol, α,2-dimethyl-5-nitro- [ACD/Index Name] 222-134-0 [EINECS] 3366-95-8 [RN] a,2-Dimethyl-5-nitro-1H-imidazole-1-ethanol UNII:R3459K699K секнидазол[Russian][INN] سيكنيدازول[Arabic][INN] 塞克硝唑[Chinese][INN] RP-14539, PM-185184, Flagentyl Company: Symbiomix Therapeutics Approval Status: Approved FDA September 2017 Specific Treatments: bacterial vaginosis Therapeutic Areas Obstetrics/Gynecology (Women’s Health) Infections and Infectious Diseases Solosec (secnidazole) ; Symbiomix Therapeutics; For the treatment of bacterial vaginosis , …
Enclomiphene citrate, New patent, WO 2017182097, F.I.S. – FABBRICA ITALIANA SINTETICI S.P.A
It’s only fair to share… Enclomiphene citrate, New patent, WO 2017182097, F.I.S. – FABBRICA ITALIANA SINTETICI S.P.A WO-2017182097 F.I.S. – FABBRICA ITALIANA SINTETICI S.P.A CARUANA, Lorenzo; (IT). PADOVAN, Pierluigi; (IT). DAL SANTO, Claudio; (IT) https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2017182097&recNum=1&maxRec=&office=&prevFilter=&sortOption=&queryString=&tab=PCTDescription Enclomiphene citrate is an active pharmaceutical ingredient currently under evaluation in clinical phase III for the treatment of secondary hypergonadism. …
BMS-986020
It’s only fair to share… BMS-986020 AM-152; BMS-986020; BMS-986202 cas 1257213-50-5 Chemical Formula: C29H26N2O5 Molecular Weight: 482.536 (R)-1-(4′-(3-methyl-4-(((1-phenylethoxy)carbonyl)amino)isoxazol-5-yl)-[1,1′-biphenyl]-4-yl)cyclopropane-1-carboxylic acid Cyclopropanecarboxylic acid, 1-(4′-(3-methyl-4-((((1R)-1-phenylethoxy)carbonyl)amino)-5-isoxazolyl)(1,1′-biphenyl)-4-yl)- 1-(4′-(3-Methyl-4-(((((R)-1-phenylethyl)oxy)carbonyl)amino)isoxazol-5-yl)biphenyl-4-yl)cyclopropanecarboxylic acid UNII: 38CTP01B4L For treatment for pulmonary fibrosis, phase 2, The lysophosphatidic acid receptor, LPA1, has been implicated as a therapeutic target for fibrotic disorders Lysophospholipids (LPs), including lysophosphatidic acid (LPA), sphingosine 1-phospate (S1P), …
AD 35
It’s only fair to share… AD 35 IND-120499 MF C24 H27 N3 O3 Molecular Weight, 405.49 Spiro[cyclopropane-1,5′-[5H-1,3]dioxolo[4,5-f]isoindol]-7′(6′H)-one, 6′-[2-[1-(2-pyridinylmethyl)-4-piperidinyl]ethyl]- 6′-[2-[1-(2-Pyridinylmethyl)-4-piperidinyl]ethyl]spiro[cyclopropane-1,5′-[5H-1,3]dioxolo[4,5-f]isoindol]-7′(6’H)-one 1531586-58-9 CAS FREE FORM 1531586-64-7 PHOSPHATE 1531586-62-5 HYDROCHLORIDE Zhejiang Hisun Pharmaceutical Co Ltd AD-35 is known to be a neuroprotectant, useful for treating Alzheimer’s diseases. Zhejiang Hisun Pharmaceutical is developing an oral tablet formulation of AD-35, for treating Alzheimers disease …
Novel lead compounds in pre-clinical development against African sleeping sickness
It’s only fair to share… Novel lead compounds in pre-clinical development against African sleeping sickness Med. Chem. Commun., 2017, 8,1872-1890 DOI: 10.1039/C7MD00280G, Review Article Michael Berninger, Ines Schmidt, Alicia Ponte-Sucre, Ulrike Holzgrabe This article reviews the recent progress in drug development against the African sleeping sickness. Novel lead compounds in pre-clinical development against African sleeping sickness …
NNC 45-0781
It’s only fair to share… NNC 45-0781 Molecular Formula C27H29NO3 Molecular Weight 415.5241 CAS 207277-66-5 2H-1-Benzopyran-7-ol, 3,4-dihydro-3-phenyl-4-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-, cis-(-)- (3S,4R)-3,4-Dihydro-3-phenyl-4-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-2H-1-benzopyran-7-ol 2H-1-Benzopyran-7-ol, 3,4-dihydro-3-phenyl-4-(4-(2-(1-pyrrolidinyl)ethoxy)phenyl)-, (3S,4R)- OriginatorNovo Nordisk ClassOsteoporosis therapies; Pyrrolidines; Small molecules Mechanism of ActionSelective estrogen receptor modulators PATENT WO 9818776 WO 9818771 WO 2003063859 A quantitative structure activity relationship study on cis-3,4-diaryl hydroxy chromones as high affinity partial agonists for the estrogen …
(R)-(–)-Baclofen, Arbaclofen, STX 209, AGI 006
It’s only fair to share… (R)-(–)-Baclofen, Arbaclofen, STX 209, AGI 006 Chemical Names: (R)-Baclofen; Arbaclofen; 69308-37-8; (R)-4-Amino-3-(4-chlorophenyl)butanoic acid; (-)-Baclofen; D-Baclofen Molecular Formula: C10H12ClNO2 Molecular Weight: 213.661 g/mol A GAMMA-AMINOBUTYRIC ACID derivative that is a specific agonist of GABA-B RECEPTORS. It is used in the treatment of MUSCLE SPASTICITY, especially that due to SPINAL CORD INJURIES. Its therapeutic …
ESCITALOPRAM, S-(+)-Citalopram, эсциталопрам , إيسكيتالوبرام , 艾司西酞普兰 ,
It’s only fair to share… Escitalopram (+)-Citalopram (1S)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile [ACD/IUPAC Name] (S)-citalopram 128196-01-0 [RN] 5-Isobenzofurancarbonitrile, 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-, (1S)- [ACD/Index Name] Molecular FormulaC20H21FN2O Average mass324.392 Da S-(+)-Citalopram эсциталопрам [Russian] [INN] إيسكيتالوبرام [Arabic] [INN] 艾司西酞普兰 [Chinese] [INN] Lexapro® (escitalopram oxalate) is an orally administered selective serotonin reuptake inhibitor (SSRI). Escitalopram is the pure Senantiomer (single isomer) of the racemic bicyclic phthalane derivative citalopram. Escitalopram oxalate is designated S-(+)-1-[3(dimethyl-amino)propyl]-1-(p-fluorophenyl)-5-phthalancarbonitrile oxalate with the …
(+)-(S,S)-Reboxetine succinate, Esreboxetine succinate
It’s only fair to share… Esreboxetine succinate (2S)-2-[(S)-(2-ethoxyphenoxy)(phenyl)methyl]morpholine butanedioate (1:1) (2S)-2-[(S)-(2-Ethoxyphenoxy)(phenyl)methyl]morpholine succinate (1:1) (S,S)-reboxetine succinate 635724-55-9 [RN] Esreboxetine succinate [USAN] Morpholine, 2-[(S)-(2-ethoxyphenoxy)phenylmethyl]-, (2S)-, butanedioate (1:1) Succinic acid – (2S)-2-[(S)-(2-ethoxyphenoxy)(phenyl)methyl]morpholine (1:1) UNII:XQO13W6OCH Esreboxetine is a selective norepinephrine reuptake inhibitor which was under development by Pfizer for the treatment of neuropathic pain and fibromyalgia but failed to show significant benefit over currently available medications and was discontinued.[1][2][3][4] It is the …