It’s only fair to share… SEQUENCE 1gagaauaaac uaguauucuu cuggucccca cagacucaga gagaacccgc 51caccauguuc guguuccugg ugcugcugcc ucuggugucc agccagugug 101ugaaccugac caccagaaca cagcugccuc cagccuacac caacagcuuu 151accagaggcg uguacuaccc cgacaaggug uucagaucca gcgugcugca 201cucuacccag gaccuguucc ugccuuucuu cagcaacgug accugguucc 251acgccaucca cguguccggc accaauggca ccaagagauu cgacaacccc 301gugcugcccu ucaacgacgg gguguacuuu gccagcaccg agaaguccaa 351caucaucaga ggcuggaucu ucggcaccac acuggacagc aagacccaga 401gccugcugau cgugaacaac gccaccaacg uggucaucaa agugugcgag 451uuccaguucu gcaacgaccc cuuccugggc gucuacuacc …
Category «Uncategorized»
NIROGACESTAT
It’s only fair to share… NIROGACESTAT (2S)-2-[[(2S)-6,8-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl]amino]-N-[1-[1-(2,2-dimethylpropylamino)-2-methylpropan-2-yl]imidazol-4-yl]pentanamide 489.6 g/mol, C27H41F2N5O CAS 1290543-63-3 PF-03084014, 1290543-63-3, PF-3084014, 865773-15-5 QZ62892OFJ UNII:QZ62892OFJ UNII-QZ62892OFJ нирогацестат [Russian] [INN] نيروغاسيستات [Arabic] [INN] 尼罗司他 [Chinese] [INN] ニロガセスタット; orphan drug designation in June 2018 for the treatment of desmoid tumors, and with a fast track designation Nirogacestat, also known as PF-03084014, is a potent and selective gamma secretase (GS) inhibitor with potential antitumor activity. PF-03084014 …
Umbralisib
It’s only fair to share… Umbralisib tosylate Formula C31H24F3N5O3. C7H8O3S Cas 1532533-72-4 FREE 1532533-67-7 Mol weight 743.7508 FDA APPR 2021/2/5 ウムブラリシブトシル酸塩; Treatment of cancer and B-cell related disorders Antineoplastic RP-5152; RP-5237; PI3K delta inhibitors (cancer), Rhizen/Incozen; PI3K delta inhibitors (B-cell lymphoma/hematological cancers), Incozen/Rhizen; TGR-1202; TG-1202; RV-1001; umbralisib tosylate; umbralisib; RP-5264; RP-5307; dual PI3Kdelta/CK1 inhibitor (cancer), TG Therapeutics; …
Amiodarone
It’s only fair to share… Amiodarone CAS : 1951-25-3 (2-Butyl-3-benzofuranyl)[4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]methanone 2-butyl-3-benzofuranyl-4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl ketone; 2-butyl-3-[3,5-diiodo-4-(b-diethylaminoethoxy)benzoyl]benzofuran Molecular Formula: C25H29I2NO3 Molecular Weight: 645.31 Percent Composition: C 46.53%, H 4.53%, I 39.33%, N 2.17%, O 7.44% In December 1985, amiodarone was approved by the FDA for the treatment of arrhythmias.[6] This makes amiodarone one of the few drugs approved by …
TROFINETIDE
It’s only fair to share… Trofinetide Molecular FormulaC13H21N3O6 Average mass315.322 Da Tofinetide , NNZ-2566 10076 853400-76-7 [RN] glycyl-2-methyl-L-prolyl-L-glutamic acid H-Gly-PMe-Glu-OH L-Glutamic acid, glycyl-2-methyl-L-prolyl- UNII-Z2ME8F52QL Z2ME8F52QL трофинетид [Russian] [INN] تروفينيتيد [Arabic] [INN] 曲非奈肽 [Chinese] [INN] IUPAC Condensed H-Gly-aMePro-Glu-OH Sequence GXE HELM PEPTIDE1{G.[*C(=O)[C@@]1(CCCN1*)C |$_R2;;;;;;;;_R1;$|].E}$$$$ IUPAC glycyl-alpha-methyl-L-prolyl-L-glutamic acid An (1-3) IGF-1 analog with neuroprotective activity. OPTICAL ROT; -52.4 ° Conc: 0.19 g/100mL; water …
IMRECOXIB
It’s only fair to share… Imrecoxib (Hengyang) CHINA 2012 osteoarthritis 2H-Pyrrol-2-one, 1,5-dihydro-3-(4-methylphenyl)-4-[4-(methylsulfonyl)phenyl]-1-propyl- 3-(4-Methylphenyl)-4-[4-(methylsulfonyl)phenyl]-1-propyl-1,5-dihydro-2H-pyrrol-2-one 395683-14-4 [RN] Imrecoxib was approved by China Food and Drug Administration (CFDA) on May 20, 2011. It was developed and marketed as 恒扬® by HengRui Pharmaceuticals. Imrecoxib is a selective COX-2 inhibitor indicated for treatment of osteoarthritis. 恒扬® is available as tablet for …
Telacebec
It’s only fair to share… Telacebec Molecular FormulaC29H28ClF3N4O2 Average mass557.006 Da Telacebec, IAP6, CAS No. 1334719-95-7 телацебек [Russian] [INN] تيلاسيبيك [Arabic] [INN] 特雷贝克 10573 1334719-95-7 [RN] 55G92WGH3X 6-Chloro-2-ethyl-N-(4-{4-[4-(trifluoromethoxy)phenyl]-1-piperidinyl}benzyl)imidazo[1,2-a]pyridine-3-carboxamide Imidazo[1,2-a]pyridine-3-carboxamide, 6-chloro-2-ethyl-N-[[4-[4-[4-(trifluoromethoxy)phenyl]-1-piperidinyl]phenyl]methyl]- Q203 Q-203 T56 AN DNJ C2 HG BVM1R D- AT6NTJ DR DOXFFF Qurient Therapeutics and Russia licensee Infectex are developing telacebec, an oral formulation which targets QcrB subunit of the cytochrome …
IGURATIMOD
It’s only fair to share… Iguratimod Molecular FormulaC17H14N2O6S Average mass374.368 Da UNII-4IHY34Y2NV игуратимод إيغوراتيمود 艾拉莫德 123663-49-0 [RN] 3-Formylamino-7-methylsulfonylamino-6-phenoxy-4H-1-benzopyran-4-one 4IHY34Y2NV 8176 IGU Methanesulfonamide, N-[3-(formylamino)-4-oxo-6-phenoxy-4H-1-benzopyran-7-yl]- N-(3-Formamido-4-oxo-6-phenoxy-4H-chromen-7-yl)methanesulfonamide product patent US4954518 Research Code： T-614 Trade Name： Iremod® / Kolbet® / Careram® MOA： Nuclear factor NF-κB activation inhibitor Indication： Rheumatoid arthritis Status： Approved Company： Simcere (Originator) , Taisho Toyama,Eisai Sales： ATC Code： Approved Countries or Area JP …
RIDINILAZOLE
It’s only fair to share… RIDINILAZOLE SMT19969 Molecular FormulaC24H16N6 Average mass388.424 Da ридинилазол [Russian] [INN] ريدينيلازول [Arabic] [INN] 利地利唑 [Chinese] [INN] リジニラゾール; 10075 2,2′-Di(4-pyridinyl)-3H,3’H-5,5′-bibenzimidazole 308362-25-6 [RN] 6,6′-Bi-1H-benzimidazole, 2,2′-di-4-pyridinyl- Summit Therapeutics (formerly Summit Corp ) is developing ridinilazole the lead compound from oral narrow-spectrum, GI-restricted antibiotics, which also include SMT-21829, for the treatment of Clostridium difficile infection and prevention of recurrent disease. …
OI 338
It’s only fair to share… OI 338 OI338GT (NN1953) NNC0123-0000-0338 Insulin oral (NN 1953); Insulin-338-GIPET-I; LAI 338; NN 1438; NN-1953; NNC-0123-0000-0338; NNC0123-0338; OI-338GT; Oral insulin 338 C10 OriginatorNovo Nordisk ClassAntihyperglycaemics; Insulins; Pancreatic hormones Mechanism of ActionOrnithine decarboxylase stimulants; Phosphokinase stimulants; Protein tyrosine kinase stimulants Phase IIType 1 diabetes mellitus; Type 2 diabetes mellitus 28 Jul …